Navigation Links
BMI criteria for obesity surgery should be lowered, UT Southwestern researcher suggests
Date:12/17/2007

DALLAS Dec. 18, 2007 UT Southwestern Medical Center researchers have found that the existing body mass index criteria for obesity surgery often excludes a group of obese patients at risk of cardiovascular disease.

The study, appearing in the December issue of the journal Surgery for Obesity and Related Diseases, is among the first to evaluate the risk-factor relationship between body mass index (BMI) and cardiovascular disease as it relates to bariatric surgery criteria, said Dr. Edward Livingston, chairman of GI/endocrine surgery at UT Southwestern and lead author of the study.

Our results show that cardiovascular risk factors do not necessarily worsen with increasing obesity, Dr. Livingston said. They also support the concept that obesity, by itself, doesnt trigger an adverse cardiovascular risk profile or increased risk of death.

The researchers examined patient data from the Third National Health and Nutrition Examination Survey database for the presence of known cardiovascular risk factors as a function of obesity. The survey was a cross-sectional study conducted from 1988 to 1994. All 17,234 participants had a BMI greater than 20.

BMI is a weight-to-height ratio commonly used in doctors offices to gauge obesity. A normal BMI is between 18.5 and 25, whereas someone with a BMI of 40 or more is at least 100 pounds over their recommended weight and is considered morbidly obese.

Bariatric weight-loss surgery is currently recommended for patients with a BMI greater than 40, as well as for patients with a BMI greater than 35 who also suffer from a life-threatening illness, such as non-insulin dependent diabetes, sleep apnea or heart disease.

The study findings show that some morbidly obese patients have better cardiovascular disease risk profiles than those who are less obese. In particular, the researchers found that cardiovascular risk factors can be much worse in many individuals with a BMI as low as 30 than they are for some surgical candidates with higher BMIs.

This suggests that some patients who are obese but not morbidly obese could benefit from bariatric surgery, which can help reduce cardiovascular disease, said Dr. Livingston.

Dr. Nicola Abate, associate professor of internal medicine in the Center for Human Nutrition at UT Southwestern and the studys co-author, said its possible that very obese patients simply have a greater capacity to store excessive calories in their adipocytes, or fat cells, thereby preventing excessive fat from spilling into the bloodstream, where it contributes to heart disease.

Our findings suggest that there is a group of individuals who have an almost unlimited ability to store excess calories as fat. This prevents changes in plasma metabolites, such as triglycerides and cholesterol, which promote risk for heart disease, Dr. Abate said. In contrast, those who cant store as much fat and who only accumulate fat in the upper body often have excessive plasma concentrations of triglycerides and cholesterol, which will increase their risk for heart disease. Even though their BMI may be below the current recommended cutoff, these patients could potentially benefit from bariatric surgery.


'/>"/>

Contact: Kristen Holland Shear
kristen.hollandshear@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
Source:Eurekalert

Related biology news :

1. Childhood obesity indicates greater risk of school absenteeism, Penn study reveals
2. Obesity and lack of exercise could enhance the risk of pancreatic cancer
3. Obesity and the central nervous system -- the state of the art
4. Obesity-related hormone is higher in children with Down syndrome
5. Australian researchers develop treatment to treat obesity
6. Study suggests link between obesity, poor bone health
7. Minimally invasive heart surgery research wins NIH award
8. Pennsylvania Hospital surgeon receives grant to develop molecular cardiac surgery
9. UT Southwestern researchers identify hundreds of genes controlling female fertility
10. Researchers identify proteins involved in new neurodegenerative syndrome
11. Texas researchers and educators head for Antarctica
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/11/2017)... , April 11, 2017 NXT-ID, ... security technology company, announces the appointment of independent Directors Mr. ... to its Board of Directors, furthering the company,s corporate ... ... NXT-ID, we look forward to their guidance and benefiting from ...
(Date:4/5/2017)... April 5, 2017  The Allen Institute for Cell ... Explorer: a one-of-a-kind portal and dynamic digital window into ... data, the first application of deep learning to create ... cell lines and a growing suite of powerful tools. ... these and future publicly available resources created and shared ...
(Date:4/5/2017)... KEY FINDINGS The global market for stem ... 25.76% during the forecast period of 2017-2025. The rise ... growth of the stem cell market. Download ... The global stem cell market is segmented on the ... cell market of the product is segmented into adult ...
Breaking Biology News(10 mins):
(Date:4/27/2017)... ... April 27, 2017 , ... ... digital pathology, today announced their digital pathology technology has the potential to eliminate ... five medical centers in The Netherlands as part of the 2017 ISBI ...
(Date:4/27/2017)... ... April 27, 2017 , ... ... flow controllers based on capillary thermal mass flow technology provide exponentially more accurate ... applications. Over 80% of all industrial processes—such as those involving chemical reactions, ...
(Date:4/27/2017)... a distinguished resource for research, development and commercialization of ... Thomas C. Seoh as President and CEO. Mr. Seoh ... becomes Executive Chairman and will continue to serve as ... Thomas Seoh commented, "I am excited and honored ... firm,s remarkable team of life science professionals, all of ...
(Date:4/26/2017)... ... April 26, 2017 , ... Baltimore bio ... MailGuardtm mail security screening solution at the National Postal Forum 2017 in Baltimore, ... a fast, highly accurate, easy to use and low cost threat detection solution ...
Breaking Biology Technology: