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BMC awarded NIH grant to study brain abnormalities in former ELGANS patients
Date:9/9/2011

questionnaire/interview activities with the parent/guardian. About 20 percent of the cohort will return on a separate day for an added evaluation for autism (ADOS), and 20 percent will return on a separate day for a brain MRI study.

"In addition to supporting a potential role for many previously identified antecedents of brain damage in ELGANs, our previous study was the first to provide strong evidence that brain damage in extremely preterm infants is associated with microorganisms in placenta parenchyma. We hope to add to those findings thanks to the generosity of this NIH grant," Kuban said.

"We anticipate that this work will help establish a method for identifying infants at high risk as targets for clinical trials of prophylactic and therapeutic interventions. Ultimately, we hope that the result of our work will broaden and redirect the rationale for preventive and therapeutic interventions intended to reduce the risk and severity of neurodevelopmental disorders in ELGANs," added Kuban.


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Contact: Gina DiGravio
gina.digravio@bmc.org
617-638-8480
Boston University Medical Center
Source:Eurekalert

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