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BIDMC scientist John Rinn, Ph.D., receives Damon-Runyon Rachleff Innovation Award
Date:1/22/2009

BOSTON AND NEW YORK The Damon Runyon Cancer Research Foundation announced today that Beth Israel Deaconess Medical Center researcher John Rinn, PhD, has been awarded a 2009 Damon Runyon-Rachleff Innovation Award. The three-year $450,000 prize is made to early-career researchers who are using "novel approaches to fighting cancer."

Rinn, who is also a member of the faculty at the Broad Institute in Cambridge and Assistant Professor of Pathology at Harvard Medical School is one of three investigators selected from nearly 300 applicants nationwide.

"We're thrilled with the caliber of the people and the proposals received this year," noted Andy Rachleff, who together with his wife Debbie partnered with the Damon Runyon Foundation to create the Innovation Award in 2007. "A large number of investigators submitted applications that proposed to take significant risks in order to achieve breakthroughs in the prevention, diagnosis and treatment of cancer. As a venture capitalist, I look for visionaries with daring ideas. It is exciting to see these qualities in all of the winning proposals."

Adds Lorraine Egan, Executive Director of the Damon Runyon Cancer Research Foundation, "Most research funded today is safe and incremental. For large breakthroughs, we need to take risks. We're delighted to once again be funding such innovative ideas."

Rinn's work focuses on a class of molecule known as lincRNAs, an acronym for large intergenic non-coding RNAs. Based on earlier research that identified the first lincRNA a molecule called HOTAIR that plays a major role is establishing the distinct identities of skin cells -- Rinn proposes to further decipher the workings of these molecules, believing that they may have an important role in tumor function.

"LincRNAs could herald a new paradigm in our understanding of cellular transformation, including how cancerous cells metastasize," says Rinn. "Defining the roles of these RNA molecules
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Contact: Bonnie Prescott
bprescot@bidmc.harvard.edu
617-667-7306
Beth Israel Deaconess Medical Center
Source:Eurekalert

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