Navigation Links
BIDMC scientist John Rinn, Ph.D., receives Damon-Runyon Rachleff Innovation Award

BOSTON AND NEW YORK The Damon Runyon Cancer Research Foundation announced today that Beth Israel Deaconess Medical Center researcher John Rinn, PhD, has been awarded a 2009 Damon Runyon-Rachleff Innovation Award. The three-year $450,000 prize is made to early-career researchers who are using "novel approaches to fighting cancer."

Rinn, who is also a member of the faculty at the Broad Institute in Cambridge and Assistant Professor of Pathology at Harvard Medical School is one of three investigators selected from nearly 300 applicants nationwide.

"We're thrilled with the caliber of the people and the proposals received this year," noted Andy Rachleff, who together with his wife Debbie partnered with the Damon Runyon Foundation to create the Innovation Award in 2007. "A large number of investigators submitted applications that proposed to take significant risks in order to achieve breakthroughs in the prevention, diagnosis and treatment of cancer. As a venture capitalist, I look for visionaries with daring ideas. It is exciting to see these qualities in all of the winning proposals."

Adds Lorraine Egan, Executive Director of the Damon Runyon Cancer Research Foundation, "Most research funded today is safe and incremental. For large breakthroughs, we need to take risks. We're delighted to once again be funding such innovative ideas."

Rinn's work focuses on a class of molecule known as lincRNAs, an acronym for large intergenic non-coding RNAs. Based on earlier research that identified the first lincRNA a molecule called HOTAIR that plays a major role is establishing the distinct identities of skin cells -- Rinn proposes to further decipher the workings of these molecules, believing that they may have an important role in tumor function.

"LincRNAs could herald a new paradigm in our understanding of cellular transformation, including how cancerous cells metastasize," says Rinn. "Defining the roles of these RNA molecules in cancer could open up new avenues for better diagnostics and therapeutics. If we can crack the 'code' of how lincRNAs establish normal states, we can understand what goes wrong in cancers. We could then engineer these RNA molecules to target and silence cancer genes, thus restoring the genome back to its proper identity."

"John Rinn's work pushes the scientific envelope," adds BIDMC Chairman of Pathology Jeffrey Saffitz, MD, PhD. "His innovative ideas and willingness to challenge traditional scientific thinking are translating into key discoveries, many of which have been developed through novel experimental methods. He truly encompasses a spirit of risk-taking and innovation."

After completing his undergraduate work in chemistry at the University of Minnesota, Rinn received a doctorate in molecular biophysics and biochemistry from Yale University. He is the recipient of numerous awards and fellowships including the AAAS Biovision Fellowship, the McDougal Fellowship and the Damon Runyon Foundation Postdoctoral Fellowship. Prior to joining BIDMC and the Broad Institute, Rinn was a member of the Howard Chang laboratory at Stanford University.


Contact: Bonnie Prescott
Beth Israel Deaconess Medical Center

Related biology news :

1. UK scientists working to help cut ID theft
2. Scientists show that mitochondrial DNA variants are linked to risk factors for type 2 diabetes
3. Comet probes reveal evidence of origin of life, scientists claim
4. Scientists link fragile X tremor/ataxia syndrome to binding protein in RNA
5. Male elephants get photo IDs from scientists
6. Scientists retrace evolution with first atomic structure of an ancient protein
7. Muscle mass: Scientists identify novel mode of transcriptional regulation during myogenesis
8. Carnegie Mellon scientists develop nanogels that enable controlled delivery of carbohydrate drugs
9. Clemson scientists shed light on molecules in living cells
10. Scientists tackle mystery mountain illness
11. T. rex quicker than Becks, say scientists
Post Your Comments:
(Date:5/12/2016)... -- , a brand of Troubadour Research ... the Q1 wave of its quarterly wearables survey. A ... to a program where they would receive discounts for ... "We were surprised to see that so ... , CEO of Troubadour Research, "primarily because there are ...
(Date:5/3/2016)... , May 3, 2016  Neurotechnology, a ... the MegaMatcher Automated Biometric Identification System (ABIS) ... large-scale multi-biometric projects. MegaMatcher ABIS can process multiple ... using any combination of fingerprint, face or iris ... MegaMatcher SDK and MegaMatcher Accelerator , ...
(Date:4/28/2016)... First quarter 2016:   , Revenues amounted ... quarter of 2015 The gross margin was 49% (27) ... the operating margin was 40% (-13) Earnings per share ... operations was SEK 249.9 M (21.2) , Outlook   ... M. The operating margin for 2016 is estimated to ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... , June 23, 2016 Apellis ... Phase 1 clinical trials of its complement C3 ... single and multiple ascending dose studies designed to ... (PD) of subcutaneous injection in healthy adult volunteers. ... (SC) either as a single dose (ranging from ...
(Date:6/23/2016)... 23, 2016 Andrew ... Published recently in ... journal from touchONCOLOGY, Andrew D Zelenetz , ... cancer care is placing an increasing burden on ... biologic therapies. With the patents on many biologics ...
(Date:6/23/2016)... San Francisco, CA (PRWEB) , ... June 23, ... ... capture (EDC) software, is exhibiting at the Pennsylvania Convention Center and will showcase ... DIA Annual conference. ClinCapture will also be presenting a scientific poster on Disrupting ...
(Date:6/23/2016)... Connecticut (PRWEB) , ... June 23, 2016 , ... ... introduce a new line of intelligent tools designed, tuned and optimized exclusively for ... September 12–17 in Chicago. The result of a collaboration among several companies with ...
Breaking Biology Technology: