Navigation Links
BGI reports the completed sequence of foxtail millet genome
Date:5/13/2012

May 13, 2012, Shenzhen, China BGI, the world's largest genomics organization, in cooperation with Zhangjiakou Academy of Agricultural Science, has completed the genome sequence and analysis of foxtail millet (Setaria italica), the second-most widely planted species of millet. This study provides an invaluable resource for the study and genetic improvement of foxtail millet and millet crops at a genome-wide level. Results of the latest study were published online today in Nature Biotechnology.

Foxtail millet is an important cereal crop providing food and feed in semi-arid areas. It is the top-one crop in ancient China. It promises to serve as an important model for comparative genomics and functional gene studies, due to its small genome size (~490M), self-pollination, rich genetic diversity (~6000 varieties), complete collection of germplasm, and the availability of efficient transformation platforms. It is also evolutionarily close to several important biofuel grasses, such as switchgrass and napier grass.

"The lower yield of traditional cultivars has largely limited cultivation and utilization of foxtail millet." said Dr. Gengyun Zhang, Vice President of BGI. "Hybrid cultivars, recently developed by Professor Zhihai Zhao in Zhangjiakou Agricultural Academy of Science, doubled the yield of foxtail millet. I expect that the results of this study could set an example of applying the genome sequence to better understanding and quicker developing new varieties of a neglected crop with higher yield, better grain quality and stress tolerance."

In this study, researchers from BGI carried out next-generation sequencing and de novo assembly for "Zhang gu", one strain of foxtail millet from Northern China. The final genome assembly was 423 Mb, and 38,801 protein-coding genes have been predicted, of which ~81% were expressed. They also developed a high density genetic linkage map using a set of genetic markers identified by resequencing another strain named "A2" and an F2 population of "Zhang gu" crossing A2. A2 is the widely used female strain of hybrid foxtail millet.

Comparing the foxtail millet genome and rice genome, researchers found the rules and changing tendency of the foxtail millet chromosomes, which are important for understanding the millet genome evolution. "We found nine foxtail millet chromosomes were formed after three chromosomal reshuffling events." said Dr. Zhang, "Of the three events, two occurred after divergence of foxtail millet from rice, followed by a specific reshuffling after divergence of millet from sorghum."

C4 plants are better adapted than C3 plants in environments with higher daytime temperature, intense sunlight, drought, or nitrogen or CO2 limitation. Foxtail millet is a diploid C4 panicoid crop species. With its genome available, researchers comprehensively analyzed the evolution of several key genes in C4 photosynthesis pathway. Results indicated that all the genes involved in C4 carbon fixation pathway also existed in C3 plants. Thus, researchers predicted that the emergence of C4 pathway could result from expressional and/or functional modifications of these genes.

The genome sequence of foxtail millet could facilitate mapping of quantitative trait loci. In this study, researchers used the foxtail millet genome to aid identification of herbicide resistant genes, and they accurately identified the gene for sethoxydim resistance.

"The decoding of whole genome sequence is an essential and important step to reveal the secrets of genetic control of crops, which could serve as an important platform for biological studies and breeding. " added by Dr. Zhang.


'/>"/>
Contact: Jia Liu
liujia@genomics.cn
BGI Shenzhen
Source:Eurekalert

Related biology news :

1. Radiologists study necessity of additional imaging recommendations in PET/CT oncologic reports
2. Aware, Inc. Reports First Quarter 2012 Financial Results
3. Aware, Inc. Reports Fourth Quarter and 2011 Financial Results
4. Cell Press launches a new open-access journal, Cell Reports
5. Ambry Genetics Reports Results from Clinical Diagnostic Exome™ Testing of Three Patients
6. BGI reports study results on frequent mutation of genes encoding UMPP components in kidney cancer
7. BGI reports pig parasites genomic sequence provides new clues for parasitic diseases research
8. Aware, Inc. Reports Third Quarter 2011 Financial Results
9. Extreme melting on Greenland ice sheet, reports CCNY team
10. Study reports predictors of poor hand hygiene in an emergency department
11. Reports highlight the evolving role of clinical microbiology laboratories
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/8/2016)... PRAGUE, Czech Republic , February 8, 2016 ... first EU-regulated global payment platform which presents innovation ... Voice Biometrics Authentication feature called VoiceKey. --> ... payment platform which presents innovation for clients, comfort ... feature called VoiceKey. --> Worldcore ...
(Date:2/4/2016)... LONDON , Feb. 4, 2016 ... is apparently one of the most popular hubs ... Project, MetaHIT and other huge studies of human ... that past few years, the microbiome space has ... applied biomedical research. This report focuses on ...
(Date:2/3/2016)... -- --> --> ... Identification System Market by Component (Hardware and Software), Search ... Government, Healthcare, and Transportation) and Geography - Global Forecast ... to be worth USD 8.49 Billion by 2020 at ... The transformation and technology evolution from the manual process ...
Breaking Biology News(10 mins):
(Date:2/9/2016)... and LONDON , February 9, 2016 /PRNewswire/ ... tech replace paper and protect IP   ... laboratory notebook (ELN) will be rolled out in ... and development (R&D) and protect valuable IP. Users will be ... a specific researcher or experiment as part of the application, ...
(Date:2/9/2016)... 9, 2016 DelveInsight,s, ... report provides in depth insights on the ... the Protein-Tyrosine Phosphatase 1B (PTP1B) Inhibitors. The ... various stages of development including Discovery, Pre-clinical, ... and Preregistration. Report covers the product clinical ...
(Date:2/8/2016)... 2016  CytRx Corporation (NASDAQ: CYTR ), ... oncology, today announced that it has entered into ... Technology Growth Capital, Inc. and Hercules Technology III, ... --> --> ... financing under the loan and security agreement.  The ...
(Date:2/8/2016)... ... 2016 , ... Thomas J. Todorow has joined the University ... Corporate Services and the Chief Financial Officer at The Children’s Hospital of Philadelphia ... Care Contracting, Supply Chain, and Investments. , Prior to joining CHOP and The ...
Breaking Biology Technology: