Navigation Links
BGI contributes whole genome sequencing and bioinformatics expertise to potato genome research
Date:7/11/2011

July 11, 2011, Shenzhen, China BGI (previously known as the Beijing Genomics Institute), the largest genomic organization in the world, announced today that it was among the research organizations comprising the Potato Genome Sequencing Consortium (PGSC) that completed the genome sequence and analysis of the tuber crop potato, published as an Advance Online Publication in Nature.

This study marks an important milestone in Potato (Solanum tuberosum L.) genome research, revealing new insights into the evolutionary history of the potato genome, causes of inbreeding depression, and potential mechanisms of tuber initiation and development. These insights will generate great interest among botanists and breeders worldwide and facilitate the genetic engineering of this vital crop.

"BGI and its collaborators carried out the de novo sequencing, genome assembly and annotation of the potato genome, elucidating the evolutionary history of the genome and providing the foundation for biological analysis," stated Xun Xu, Vice President of Research and Development at BGI, and co-senior author of the report.

With the advanced genome sequencing capability of BGI, the homozygous doubled-monoploid DM1-3 516 R44 (DM) potato clone was sequenced by whole genome shotgun sequencing (WGS) approach with high coverage depths. The genome was then assembled by BGI's Short Oligonucleotide Analysis Package, SOAPdenovo, and 86% of the estimated total genome (844Mb) was assembled.

Researchers from BGI also aided in the potato gene annotation, of which 39,031 protein-coding genes were predicted. It is reported that at least two genome duplication events present in potato, indicating a paleopolyploid origin. Findings related with haplotype diversity, tuber biology and disease resistance are also reported.

"We found important genetic basis related to inbreeding depression and tuber biology based on our bioinformatics analysis," said Xu Xun, who considers the potato as one of the most important plant genomes in light of growing food shortages due to global population growth and climate change.

BGI is the only genomic organization with an extensive focus on agricultural genomics research. Its accomplishments include sequencing the rice genome, silkworm genome, cucumber genome, soybean genome and maize genome, among others. In January 2010, BGI launched the "1,000 Plant & Animal Reference Genomes Project" with the goal of generating reference genomes for 1,000 economically and scientifically important plant/animal species. BGI's 2nd International Conference on the Progress of "1000 Plant & Animal Reference Genomes Project" is being held in Shenzhen from July 10-12, 2011.

Reporting from the conference, Dr. Bicheng Yang, Director of Global Marketing at BGI stated, "Together with our collaborators, so far we have initiated 505 plant and animal genome projects, completed fine or draft genome maps for over 100 species and finished the sequencing of about 200 species. Many other genomes are undergoing active sequencing." She congratulated the PGSC consortium on its breakthrough in potato genome research and said BGI is proud to be a contributor to the project.

Last week, July 6, at Bio-IT APAC Conference & Expo 2011, BGI released SOAPdenovo 2, the latest update of BGI's SOAPdenovo package. SOAPdenovo 2 is reported to assemble genomes with improved efficiency and consistency, and can support a broader range of analyses. SOAPdenovo 2 can be downloaded at http://soap.genomics.org.cn/.

"BGI is making continuous efforts for the advancement of plant and animal genomes research. We will provide the most advanced infrastructure for our partners and look for more collaboration in this field." stated Dr. Yang. The progress of "1000 Plant & Animal Reference Genomes Project" can be found at http://ldl.genomics.org.cn/page/pa-research.jsp.


'/>"/>

Contact: Lei Su
BGI-Marketing@genomics.cn
07-552-528-3805
Beijing Genomics Institute
Source:Eurekalert

Related biology news :

1. UT Southwestern researchers find protein breakdown contributes to pelvic organ prolapse
2. Weizmann Institute scientists discover: A protein that contributes to obesity
3. Researchers find fat turns into soap in sewers, contributes to overflows
4. Dodds contributes to new national study on nitrogen water pollution
5. Scientists discover molecular switch that contributes to cellular aging process
6. Think saturated fat contributes to heart disease? Think again
7. Texas A&M spring graduate contributes to mental retardation research published in Nature
8. Scientists discover new genetic variation that contributes to diabetes
9. IFAR contributes to study that finds genes that influence the start of menstruation
10. New research shows high-quality protein in eggs contributes to power, strength and energy
11. Deranged calcium signaling contributes to neurological disorder, UT Southwestern researchers find
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/31/2016)... R.I. , March 31, 2016  Genomics firm ... of founding CEO, Barrett Bready , M.D., who ... members of the original technical leadership team, including Chief ... President of Product Development, Steve Nurnberg and Vice President ... returned to the company. Dr. Bready served ...
(Date:3/23/2016)... March 23, 2016 ... Sicherheit Gesichts- und Stimmerkennung mit Passwörtern ... (NASDAQ: MESG ), ein führender Anbieter ... Unternehmen mit SpeechPro zusammenarbeitet, um erstmals dessen ... wird die Möglichkeit angeboten, im Rahmen mobiler ...
(Date:3/22/2016)... Ontario , PROVO and ... Newborn Screening Ontario (NSO), which operates the ... for molecular testing, and Tute Genomics and UNIConnect, ... management technology respectively, today announced the launch of a ... next-generation sequencing (NGS) testing panel. NSO ...
Breaking Biology News(10 mins):
(Date:6/24/2016)... ... June 24, 2016 , ... While the majority of commercial spectrophotometers and fluorometers ... the 6000i models are higher end machines that use the more unconventional z-dimension of ... beam from the bottom of the cuvette holder. , FireflySci has developed several ...
(Date:6/23/2016)... 2016 /PRNewswire/ - FACIT has announced the creation ... biotechnology company, Propellon Therapeutics Inc. ("Propellon" or "the ... a portfolio of first-in-class WDR5 inhibitors for the ... WDR5 represent an exciting class of therapies, possessing ... for cancer patients. Substantial advances have been achieved ...
(Date:6/23/2016)... 2016  The Biodesign Challenge (BDC), a university competition ... harness living systems and biotechnology, announced its winning teams ... New York City . The ... projects at MoMA,s Celeste Bartos Theater during the daylong ... senior curator of architecture and design, and Suzanne ...
(Date:6/23/2016)... Apellis Pharmaceuticals, Inc. today announced positive ... its complement C3 inhibitor, APL-2. The trials were ... studies designed to assess the safety, tolerability, pharmacokinetics ... healthy adult volunteers. Forty subjects were ... dose (ranging from 45 to 1,440mg) or repeated ...
Breaking Biology Technology: