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BGI and Collaborators Announce New Clues Found in Tracing the Origin of the Deadly E. coli Strain and Appeal for the Sharing of Additional Data
Date:6/5/2011

One may however remember that a strain with a similar surface antigen was isolated in Germany in 2001," stated Antoine Danchin, Ph.D., D. Sci., (microbiologist and founder of the HKU-Pasteur Research Centre). Dr. Danchin further stresses this in a recent posting:  "Knowing the kinship between the present strain and the older one will be of the utmost importance." (http://www.normalesup.org/~adanchin/populus/journalist.html )

This comparative work is now of the upmost urgency, so please contact us caosujie@genomics.org.cn if you would like to collaborate in this effort by contributing samples or data from strain HUSEC041/01-09591.

The international community "crowdsourcing" and analyzing our most up-to-date genomic data now has a repository to keep this preliminary analysis together, and we would recommend scientists use our latest improved assembly (http://www.ncbi.nlm.nih.gov/bioproject/67657) and follow the repository and our Twitter feed (@BGI_Events) for the most up-to-date announcements and data: https://github.com/ehec-outbreak-crowdsourced/BGI-data-analysis

*Technical note: while there have been some reports that the sequence of MLST genes of 2001 Germany isolate and the 2011 outbreak strain may have minor differences (http://scienceblogs.com/mikethemadbiologist/2011/06/i_dont_think_the_german_e_coli.php), BGI bioinformaticians believe these discrepancies are likely due to sequencing and assembly errors. Using the most recently curated assembly from BGI, we have found that the three strains do have identical MLST. The
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