BALTIMORE, June 29, 2011 /PRNewswire/ -- BD Biosciences, a segment of BD (Becton, Dickinson and Company), announced today the availability of BD Recharge™, a chemically defined (CD) cell culture media supplement for biopharmaceutical manufacturing that offers productivity comparable to yeast-based peptones.
"Chemically defined supplements are a significant advance for biopharmaceutical cell culture," said Robert Hallenbeck, Vice President, BD Biosciences – Advanced Bioprocessing. "BD Recharge provides performance comparable to undefined products, but with greater consistency, which means less risk and lower production costs for biopharmaceutical manufacturers."
The new BD Recharge cell culture media supplement, which was developed using CHO (Chinese hamster ovary) cell lines, eliminates unnecessary constituents to maximize cell viability and protein production.
Peptones are either animal-derived or animal-free supplements that are added to cell culture media to boost protein expression. Although peptones are highly effective, biopharmaceutical manufacturers are increasingly seeking CD alternatives to eliminate the variability and increased regulatory risk inherent in undefined materials.
BD Recharge is the first in a line of next-generation CD, animal-free supplements for the manufacture of biopharmaceuticals. BD Recharge is produced in the Company's fully dedicated animal-free/antibiotic-free (AF2™) facility, which sets a new standard for safety and quality for cell culture media. Products manufactured at the AF2 facility are controlled to the tertiary level — all ingredients, ingredient components and ingredient subcomponents used in the new facility are not of animal origin — significantly reducing the risks that can be associated with mixed-use facilities.
BD is a leading global medical technology company that develops, manufactures and sells medical devices, ins
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