Vancouver, BC Local scientists are now part of an International team compiling an enormous bank of resources for research into the functions of all known genes. The development of these biological resources will eventually allow scientists to know how the human genome behaves in health and disease. The BC focus is neurological, including the brain, eye, and spinal cord, and encompassing such disorders as Parkinson and Alzheimer Disease.
The project, known as CanEuCre, is led by Dr. Elizabeth M. Simpson, a Principal Investigator at the Centre for Molecular Medicine and Therapeutics, and Senior Scientist at the Child & Family Research Institute. "This is a 'tools' project," says Dr. Simpson. "It will put in the hands of scientists worldwide the tools needed to explore what every gene in the genome does, both under normal circumstances, and when diseased."
As a result of BC's investment and its world-renowned expertise in neurological genomics, Dr. Simpson and her team have joined Phase II of this international study, which involves developing tools to discover the function of mutant genes in the mouse genome.
The goal of this project is to build the tools to make findings about the pathogenesis and mechanisms of major human diseases easier. "BC's strong foundation in functional genomics has brought BC scientists to the forefront internationally with this project. The goal is that, when the project concludes in three years' time, the tools will be there for others to use in the application of true bench-to-bedside work," says Simpson.
The EUCOMMTOOLS branch of the project has attracted over 12 million euros in funding from the European Commission as part of its Framework Programme for Research and Technology Development. Genome BC is contributing an additional $2 million in funding through the CanEuCre project. Identified through the first phase of CanEuCre was the need for an even larger collaborative effort to identify th
|Contact: Jenny Boon|