Navigation Links
Award for pioneering stem cell research to mend broken bones
Date:5/24/2009

Funding from the Biotechnology and Biological Sciences Research Council (BBSRC) could lead to the development of new and better treatments for broken bones and other orthopaedic problems associated with ageing.

Nearly 4M has been awarded to scientists from the universities of Keele, Imperial College London, Nottingham and Southampton and who will work together combining stem cell science and tissue engineering to look at the development and repair of human skeletal tissue.

Fractures, bone loss due to trauma or disease and other orthopaedic conditions pose a significant clinical and socioeconomic problem, especially with an aging population, but as yet there is no large scale effective treatment for replacing or repairing damaged bones.

Professor Richard Oreffo, from the University of Southampton who is leading the study, said: "Despite intense research, significant challenges for the reconstruction of tissues such as bone remain. Bone and cartilage tissue repair is a highly complex development process. A key requirement for these regeneration strategies to succeed remains our ability to understand skeletal cell activity, develop appropriate scaffolds and to understand how the environment the cells find themselves in affects their ability to interact with other cells to form new bone or cartilage."

Over the next five years, the scientists will combine their expertise in skeletal stem cells, scaffolds and materials chemistry to identify the key growth factors, matrix proteins and physical conditions that will enhance tissue regeneration and ultimately lead to more effective skeletal repair strategies.

"We believe a paradigm shift in approach is required if we are to lead internationally in regenerative medicine. Our findings of how stem cells, scaffolds and the physical environment can be combined to induce new bone and cartilage will be used to augment and accelerate bone repair. This will allow us to develop new regimes for cartilage and bone regeneration ultimately leading to more effective treatments" explained Professor Oreffo.

The research consortium comprises Professor Alicia El Haj, Keele University, Professor Molly Stevens, Imperial College London, Professor Kevin Shakesheff, University of Nottingham and Professor Richard Oreffo, University of Southampton.

Commenting on the award, Professor Douglas Kell, BBSRC Chief Executive said: "Fractures, particularly among older people, are a major cause of morbidly and mortality, and costs the NHS billions of pounds each year. This truly multidisciplinary approach to the basic research necessary to improve our scientific understanding opens up exciting possibilities in the area of skeletal development and repair, an area where advancement is becoming increasingly urgent on both a quality of life and an economic level as our population gets older."


'/>"/>

Contact: Tracey Jewitt
press.office@bbsrc.ac.uk
44-179-341-4694
Biotechnology and Biological Sciences Research Council
Source:Eurekalert

Related biology news :

1. Ernst-Ludwig Winnacker awarded the Order of the Rising Sun
2. Society of Interventional Radiology Foundation awards $191,000 in grants
3. Supply-Chain Council Announces Winners of 2009 Supply Chain Excellence Awards
4. Civil engineers name NJITs John Schuring Educator of Year Award
5. University of Liverpool awarded $3.3 million for genomics hub
6. UCI awarded $45 million for infectious disease research
7. NOAA awards $22.5 million to Harbor Branch/FAU and UNCW for new cooperative institute
8. University awarded £1.7M to develop nanotechnology for use in health care
9. NIH grants $122 million in Institutional Development Awards
10. Georgetown Universitys Howard J. Federoff, M.D., Ph.D. receives Bernard Sanberg Memorial Award
11. March of Dimes awards $250,000 prize to scientists unraveling the causes of muscular dystrophy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/3/2016)... June 3, 2016 ... Nepal hat ein ... hochsicherer geprägter Kennzeichen, einschließlich Personalisierung, Registrierung und ... der Produktion und Implementierung von Identitätsmanagementlösungen. Zahlreiche ... im Januar teilgenommen, aber Decatur wurde als ...
(Date:6/2/2016)... NEW YORK , June 2, 2016   The ... (Weather), is announcing Watson Ads, an industry-first capability in which ... advertising, by being able to ask questions via voice or ... Marketers have long ... with the consumer, that can be personal, relevant and valuable; ...
(Date:6/1/2016)... YORK , June 1, 2016 ... Technology in Election Administration and Criminal Identification to Boost ... to a recently released TechSci Research report, " Global ... By Region, Competition Forecast and Opportunities, 2011 - 2021", ... 24.8 billion by 2021, on account of growing security ...
Breaking Biology News(10 mins):
(Date:6/27/2016)...  Sequenom, Inc. (NASDAQ: SQNM ), a ... the development of innovative products and services, announced today ... States denied its petition to review decisions ... U.S. Patent No. 6,258,540 (",540 Patent") are not patent ... Supreme Court,s Mayo Collaborative Services v. Prometheus Laboratories decision.  ...
(Date:6/27/2016)... PHILADELPHIA , June 27, 2016  Liquid ... today announced the funding of a Sponsored Research ... study circulating tumor cells (CTCs) from cancer patients.  ... changes in CTC levels correlate with clinical outcomes ... therapies. These data will then be employed to ...
(Date:6/24/2016)... ... ... Researchers at the Universita Politecnica delle Marche in Ancona combed medical journal articles ... findings are the subject of a new article on the Surviving Mesothelioma website. ... blood, lung fluid or tissue of mesothelioma patients that can help point doctors to ...
(Date:6/23/2016)... 2016 A person commits a crime, and the ... track the criminal down. An outbreak of foodborne ... Administration (FDA) uses DNA evidence to track down the bacteria ... far-fetched? It,s not. The FDA has increasingly used a complex, ... foodborne illnesses. Put as simply as possible, whole genome sequencing ...
Breaking Biology Technology: