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Autism Speaks awards $4.8 million for new research
Date:1/7/2013

ts were awarded. Technology is also the focus of a Basic & Clinical research grant awarded to Sally Ozonoff, Ph.D., of University of California, Davis, who will develop a simple video-based method that parents can use to assess ASD risk in infants and toddlers. The project will validate the use of video examples of typical and atypical behavior to help parents identify early signs of ASD. In collaboration with a company that develops software for families of children with autism, the researchers will create a secure website. There, parents can view video and rate similarities to their infant's behaviors. The goal is to enhance early screening, diagnosis and access to early intervention services.

Christina Gross, Ph.D., of Emory University, will conduct a pilot study to examine the mechanisms underlying brain dysfunction in ASD. Using a mouse model, she will test whether a drug can correct the production of ribosomal protein S6. Normalizing production of this protein may be a therapeutic target for treatment of fragile X syndrome and a subgroup of those with autism.

James Gusella, Ph.D., of Massachusetts General Hospital, will also study brain function by examining how clusters of autism-associated genetic mutations influence shared brain pathways. Prior research suggests that many autism-linked genes influence one or more shared brain pathways. If so, effective treatments could be targeted to these shared processes. Such an approach could deliver more effective and broad-based treatments than individualized, gene-targeted treatments.

Edward Quadros, Ph.D., of the State University of New York, Downstate Medical Center, will explore how folate influences fetal brain development and autism risk. He will also explore folinic acid administration as a possible treatment for individuals with ASD and cerebral folate deficiency.

GI disturbances associated with ASD will be explored by Brent Williams, Ph.D., of Columbia University, who wi
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Contact: Jane E. Rubinstein
jrubinstein@rubenstein.com
212-843-8287
Autism Speaks
Source:Eurekalert  

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Related biology news :

1. Holding a mirror to brain changes in autism
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3. Autism Speaks awards $1.1 million to fund high priority studies
4. Spontaneous gene glitches linked to autism risk with older dads
5. Gene mutation identified as contributor to autism spectrum disorders
6. Researchers across North America team up to find genetic markers for autism
7. New genes contributing to autism and related neurodevelopmental disorders uncovered
8. Research shows how PCBs promote dendrite growth, may increase autism risk
9. Common genetic variants identify autism risk in high risk siblings of children with ASD
10. MindSpec launches online Autism Reading Room
11. New treatment for irritability in autism
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Autism Speaks awards $4.8 million for new research
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