Navigation Links
Autism Speaks and SAGE® Labs develop rat models for translational autism research
Date:8/2/2012

New York, N.Y. (August 2, 2012) Autism Speaks, the world's leading autism science and advocacy organization, today announced its expanded collaboration with Sigma Advanced Genetic Engineering (SAGE) Labs, an initiative of Sigma Life, to develop the first rat models with modified autism associated genes, intended to accelerate discovery and translational autism research.

Expansion of the collaboration follows initial behavioral studies demonstrating that the first two publicly available gene knockout rats, part of the seven rats generated through the collaboration to date, exhibit hallmark characteristics of autism, such as social deficits and repetitive behaviors. Many behavioral characteristics of autism observed in these rats are not seen in other animal models currently used for autism research. SAGE Labs and Autism Speaks now plan to generate additional genetically modified rat models of key autism-associated genes, including CNTNAP2 and MET.

"Autism spectrum disorders are a complex condition with significant unmet medical needs. Although uniquely human, fundamental aspects of the biology underlying autism can be effectively modeled in animals to advance our understanding of cause and enable translation of basic scientific discovery into medical breakthroughs that improve the quality of life for individuals on the spectrum," says Robert Ring, Ph.D., Vice President of Translational Research at Autism Speaks. "These new autism-relevant rat models have already demonstrated great potential for the field. Our new agreement ensures that additional models will continue to be developed and made available to accelerate progress along the entire translational research continuum, from academia to the pharmaceutical industry."

"Modeling human conditions in rats, rather than the mice that have come to predominate preclinical studies, enables more predictive studies of complex neurobehavioral conditions. Rats are unique in that they exhi
'/>"/>

Contact: Jane E. Rubinstein
jrubinstein@rubenstein.com
212-843-8287
Autism Speaks
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Caltech researchers find evidence of link between immune irregularities and autism
2. Study examines autism law, financial burdens
3. Questionnaire completed by parents may help identify 1-year-olds at risk for autism
4. Mutations in autism susceptibility gene increase risk in boys
5. Hunting for autisms chemical clues
6. Brain scans detect early signs of autism
7. Autism Speaks awards nearly $2.9 million to fund autism research
8. MindSpec develops Autism Quiz app
9. Fish show autism-like gene expression in water with psychoactive pharmaceuticals
10. New treatment for irritability in autism
11. MindSpec launches online Autism Reading Room
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Autism Speaks and SAGE® Labs develop rat models for translational autism research
(Date:3/24/2015)...   NexID Biometrics LLC, whose spoof-mitigation technology ... announced the beginning of shipments of version 2.0 of ... company, based in Potsdam, N.Y. , ... which began here today at the Walter E. Washington ... its SDK boosts the accuracy rate range to 96.5 ...
(Date:3/23/2015)... OXFORD, Conn. , Mar. 23, 2015 NXT-ID, Inc. ... authentication company focused on the growing mobile commerce market, announces ... a new advertising campaign on CNBC television starting March 30 ... ads will commence airing in New York ... Executive Officer said: "We are excited about our new ad ...
(Date:3/19/2015)... , March 19, 2015  NXT-ID, Inc. (NASDAQ: ... focused on the growing mobile commerce market, announces its biometric ... news clip that aired this week on Washington ... In a segment "The Next Great Thing", host ... new way to pay, and ,a really big breakthrough in ...
Breaking Biology News(10 mins):NexID Begins Shipments Of Version 2.0 Fake-Finger-Detection Solution 2NXT-ID's Wocket Smart Wallet to Launch New CNBC Regional TV Ad Campaign 2NXT-ID's Wocket Smart Wallet to Launch New CNBC Regional TV Ad Campaign 3NXT-ID's Wocket Smart Wallet Featured on Fox News Segment, "The Next Great Thing" 2NXT-ID's Wocket Smart Wallet Featured on Fox News Segment, "The Next Great Thing" 3
... April 10, 2013, New York, NY A dozen ... advancements in basic and clinical cancer research at this ... 2013. Progress in immunotherapy and epigenetics led the program ... therapy. "With new immunotherapy agents available ...
... at which a child with autism is diagnosed is ... or she exhibits, new research from the University of ... nonverbal communication and repetitive behaviors, were associated with earlier ... study in the April issue of the Journal ...
... Department of Energy,s (DOE) National Renewable Energy Laboratory (NREL) ... of real-world performance from solar facilities across the country. ... Performance and Reliability Clearinghouse (O-SPaRC) will give the private ... public capital. "The O-SPaRC dataset will provide the ...
Cached Biology News:Ludwig advancements in immunotherapy and epigenetics top scientific program at AACR 2In autism, age at diagnosis depends on specific symptoms 2
(Date:3/29/2015)... 29, 2015  Caris Life Sciences® today ... small cell cervical cancer (SCCC) that shows ... the company,s panomic, comprehensive tumor profiling service, identified ... may explain sensitivities and resistance to common ... certain biomarkers may guide treatment strategies in ...
(Date:3/27/2015)... (PRWEB) March 27, 2015 Earlier this ... the promotion of hair regrowth in adult men and ... I-II or Norwood Hamilton classifications of IIa-V and Fitzpatrick ... industry plagued by products that over-promise and under-deliver, FDA ... renewing faith and confidence among more than 80 million ...
(Date:3/27/2015)... 2015  Neogen Corporation (NASDAQ: NEOG ) announced ... trading plan in accordance with Securities and Exchange Commission ... of Neogen Corporation, is a minority owner of this ... Herbert does not have control of this ... is only for a portion of the shares owned ...
(Date:3/27/2015)... 2015 Working in collaboration with the ... London , Richmond Pharmacology is the first centre ... study for an investigational RNAi therapeutic being developed for the ... nerves and heart. Read press release ... Based at St Georges University of London ...
Breaking Biology Technology:Study Using Caris Molecular Intelligence Multiplatform Tumor Profiling Identifies Potential Treatment Strategies for Small Cell Cervical Cancer 2Study Using Caris Molecular Intelligence Multiplatform Tumor Profiling Identifies Potential Treatment Strategies for Small Cell Cervical Cancer 3Dr. Robert Leonard Applauds FDA Clearance of Capillus272Pro™ Hair Loss Laser Cap 2Neogen CEO adopts 10b5-1 Trading Plan 2
... today announced that Solomon Steiner, Chairman and CEO of ... Hidden Gems,Conference in New York, NY on October 8th ... a link to a live audio webcast of the,presentation ... http://www.biodel.com . A replay of the presentation will be ...
... Awarded for Chemistry and Automation as well as Immunoassay ... ... 4 Siemens Medical Solutions,Diagnostics, (http://www.siemens.com/diagnostics ), announced ... Systems, (http://www.medassets.com ), a,Group Purchasing Organization (GPO) and ...
... Dillahunty, Vice,President, Intellectual Property of Oncolytics Biotech Inc. (TSX: ... Company at BIO,InvestorForum 2007 on Thursday, October 11 at ... Palace Hotel in San Francisco from October 9-11, 2007. ... is available on the,company,s website at http://www.oncolyticsbiotech.com . ...
Cached Biology Technology:Biodel Inc. to Present at Natixis Bleichroeder Hidden Gems Conference on October 8, 2007 2MedAssets Supply Chain Systems Selects Siemens Medical Solutions Diagnostics for Chemistry, Automation and Immunoassay Solutions 2MedAssets Supply Chain Systems Selects Siemens Medical Solutions Diagnostics for Chemistry, Automation and Immunoassay Solutions 3Media Advisory - Oncolytics Biotech Inc. to Present at BIO InvestorForum 2007 2
MOUSE ANTI HUMAN COMPLEMENT SC5B-9...
MOUSE ANTI SIMIAN VIRUS 5 Immunogen: Simian virus 5...
... Beagle serum is collected from fasted Beagle canines ... Available Anticoagulants: N-02: Citrate ... K2EDTA N-08: Potassium Oxalate N-10: ... N-05: ACD N-07: CPD ...
MOUSE ANTI BOVINE TROPONIN I...
Biology Products: