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Australian researchers develop treatment to treat obesity
Date:11/6/2007

hers injected that mouse with an antibody that mopped up MIC-1, the weight loss was reversed. In effect, they rescued the mouse from the excessive influence of MIC-1.

It is hoped that in the near future, the MIC-1 findings will prevent a sizeable proportion of advanced cancer patients from literally wasting away. The team from St. Vincents Hospital hope to develop a human antibody and run clinical trials in the next few years.

Professor Breit who, since discovering the MIC-1 gene in the 1990s, has conducted several internationally published studies relating to the genes influence on coronary disease, miscarriage and cancer. He now believes the findings could also have a significant impact on a range of appetite-related disorders.

Injecting mice with MIC-1 protein also made them stop eating, suggesting that it may be possible to use this to advantage for treating patients with severe obesity, he said.


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Contact: Susi Hamilton
susi.hamilton@unsw.edu.au
61-422-934-024
University of New South Wales
Source:Eurekalert

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