Navigation Links
Attention! End of traffic jam!
Date:11/7/2011

ng activity, it diffuses with the microtubule-brick into solution. However, due to the traffic jam of motor proteins, a fresh supply is already present. Hence, the rate of microtubule shortening is directly connected to the speed at which the single molecular motor depolymerizes the microtubule.

The situation changes dramatically if there are significantly less motor proteins in solution. In this case, the supply of motor proteins becomes the limiting factor. The disassembly speed is now governed by the quantity of motors arriving at the microtubule tip. Consequently the disassembly mechanism differs significantly from the one for higher motor concentrations. In particular, the depolymerization speed becomes length dependent. "From existing experiments, we knew that these collective effects are important for the system. What we didn't expect is that the properties of single motors completely vanish behind the motor group's performance", tells Louis Reese first author of the study.

With their calculations, the physicists from Munich contribute to a better understanding of existing experiments on microtubule disassembly. For example, a phenomenon discussed among scientists is that the speed at which microtubules are depolymerized by motors depends on the microtubule length: the longer the microtubule, the more motor proteins can bind to it. Their theoretical model explains these basic functional properties of this system and in this vein it puts the existing experimental results into a larger context.

"With this work we as theorists pass the ball back to experiments", reckons Erwin Frey. "It is essential for the comprehension of biological systems to identify and understand minimal functional units like the microtubule motor interaction. On this track the cell plays a central role with its multifarious building blocks and functions. To understand these effects in the living cell is a declared aim of biology and biophysics".


'/>"/>
Contact: Dr. Kathrin Bilgeri
kathrin.bilgeri@lmu.de
49-892-180-6938
Ludwig-Maximilians-Universitt Mnchen
Source:Eurekalert

Page: 1 2

Related biology news :

1. Molecular chaperones traffic signaling proteins between cells in plant stem-cell maintenance pathway
2. Regulation of cell proliferation is dependent on nucleocytoplasmic trafficking
3. Road signs and traffic signals on DNA
4. Directing immune traffic -- signposts to the lung
5. Exposure to both traffic, indoor pollutants puts some kids at higher risk for asthma later
6. Geneticists coordinate action to fight against traffic in human beings
7. DNA against traffic in human beings
8. LincRNAs serve as genetic air-traffic controllers
9. DNA-Prokids: Genetic identification against traffic in human beings
10. Consumers more likely to identify healthy food using traffic light nutrition labels
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/5/2015)... , Jan. 30, 2015  It is gratifying ... power and potential for genomic science as a means ... disease prevention and treatment.  I was honored to participate ... government-funded precision medicine program. Since the ... science of genomics—from the first sequenced genome of a ...
(Date:1/22/2015)... 13, 2015  Today, FreeWavz ( www.FreeWavz.com ), the ... campaign on Fundable, https://www.fundable.com/freewavz . FreeWavz will ... capacity to meet customer demand. Logo ... http://photos.prnewswire.com/prnh/20150113/168790 Invented by Dr. ...
(Date:1/22/2015)... POINT ROBERTS, Washington , January 20, 2015 ... technology and tech stocks, releases video from the CES 2015 ... security consultant Apollo Robbins . Apollo shows ... Wocket™ biometric smart wallet, a product of NXT-ID, Inc. (NASDAQ: ...
Breaking Biology News(10 mins):J. Craig Venter, Ph.D., Co-Founder and CEO, Human Longevity, Inc. (HLI) Participates in White House Precision Medicine Event 2FreeWavz Launches on Fundable to Drive Speed-to-Market in 2015 2Apollo Robbins Talks about the Illusion of Personal Safety and How Easily Your Wallet is Stolen; If a Wocket Wallet is Stolen the Thief Can't do Anything With it! 2Apollo Robbins Talks about the Illusion of Personal Safety and How Easily Your Wallet is Stolen; If a Wocket Wallet is Stolen the Thief Can't do Anything With it! 3
... San Diego have received New Innovator Awards from the ... translation of cutting-edge science and research to improvements in ... of bioengineering at the UC San Diego Jacobs School ... of medicine at UC San Diego,s School of Medicine, ...
... in German . Scientists at the ... colleagues, have decoded the genome of the Pristionchus pacificus ... In their work, which has been published in the ... from Professor Ralf J. Sommer,s department in Tbingen have ...
... professor at the UC San Diego Jacobs School of Engineering, ... With a new $1.5 million New Innovator Award grant from ... to do just that. , The awards, announced Sept. ... of new investigators who have exceptional creativity and propose bold ...
Cached Biology News:NIH doles out $3M in new innovator awards to 2 UC San Diego faculty 2Insight into the evolution of parasitism 2Insight into the evolution of parasitism 3Generation innovation: Young UC San Diego bioengineer to use NIH grant to fuel tissue engineering 2Generation innovation: Young UC San Diego bioengineer to use NIH grant to fuel tissue engineering 3
(Date:3/2/2015)... Global Stem Cells Group.com has ... Bioengineering Co., Ltd. and its Chinese-American founder Mingjie ... stem cells training course in the City of ... Shenzhen HANK is a biotechnology company established in ... virologist, to integrate research, development, production, and sales ...
(Date:3/1/2015)... 01, 2015 Market Publishers Ltd ... quality market research promotion on Internet. MarketPublishers.com is ... worked out by DataGroup Booksellers. , Natalie Aster, ... Ltd, commented on the recent partnership agreement as ... in our team of publishers. Since 1974, the ...
(Date:2/27/2015)... Halifax, Nova Scotia (PRWEB) February 27, 2015 ... has been made aware of a fraudulent press release ... GlobeNewswire, purporting to be from Immunovaccine. This press release ... with Gilead Science, Inc. The press release did ... to the information contained within the press release. ...
(Date:2/27/2015)... Feb. 27, 2015  Pharmacyclics, Inc. (NASDAQ: ... studies for its newly developed Bruton,s tyrosine kinase ... been completed. The results of these preclinical evaluations ... Drug Administration. The feedback received from the Agency ... first-in-human study. Additional preclinical work is required to ...
Breaking Biology Technology:Global Stem Cells Group Announces Alliance with HANK Bioengineering Co., Ltd. in Shenzhen, China 2Global Stem Cells Group Announces Alliance with HANK Bioengineering Co., Ltd. in Shenzhen, China 3Market Publishers Ltd and DataGroup Booksellers Sign Partnership Agreement 2Market Publishers Ltd and DataGroup Booksellers Sign Partnership Agreement 3Immunovaccine Disclaims Hoax Press Release 2Pharmacyclics Provides Clinical Update on BTK Inhibitor for Autoimmune Diseases 2Pharmacyclics Provides Clinical Update on BTK Inhibitor for Autoimmune Diseases 3
... For the first time in Michigan, a,diseased kidney ... through a single incision., "We made several improvements ... type of procedure routinely," says Craig Rogers, M.D., Henry,Ford,s ... last week using the da Vinci Surgical System, which ...
... Provides Comprehensive Clinical Picture, Improves,Patient-Physician Communications, ... Hemophilia A patients who,use Helixate(R) FS, Antihemophilic ... tracking treatment progress in real time,thanks to ... management system recently introduced by CSL Behring. ...
... BOSTON, Aug. 25 Scimitar Equity, LLC ... Bulletin Board: VOQP), entitled,"Creating Value; Turnaround Leverages ... This review is available at website: ... a New Jersey-based biotechnology company,dedicated to becoming ...
Cached Biology Technology:State's First Single Incision Robotic Kidney Removal Performed at Henry Ford Hospital 2CSL Behring's Innovative HeliTrax(SM) System Helps Physicians Manage Hemophilia A Patients 2CSL Behring's Innovative HeliTrax(SM) System Helps Physicians Manage Hemophilia A Patients 3CSL Behring's Innovative HeliTrax(SM) System Helps Physicians Manage Hemophilia A Patients 4VioQuest Pharmaceuticals, Inc Q2/08 Review Issued by Scimitar Equity, LLC 2
... The Jouan MSC series of Class ... working conditions and certification to the ... regulation ensures that the cabinets cannot ... conditions. Natural lighting, low noise and ...
... Fluoroskan Ascent FL ... fluorometric and luminometric measurement ... long list of advanced ... and Luminoskan Ascent. Fluoroskan ...
Mouse monoclonal [AZ24] to Polo like kinase ( Abpromise for all tested applications)....
... Applied Science, which pioneered the blending of ... Fidelity and Expand Long Template PCR Systems, ... System the first product of a ... new blend combines Taq DNA Polymerase with ...
Biology Products: