Navigation Links
Atrazine causes prostate inflammation in male rats and delays puberty
Date:8/24/2010

A new study shows that male rats prenatally exposed to low doses of atrazine, a widely used herbicide, are more likely to develop prostate inflammation and to go through puberty later than non-exposed animals. The research adds to a growing body of literature on atrazine, an herbicide predominantly used to control weeds and grasses in crops such as corn and sugar cane. Atrazine and its byproducts are known to be relatively persistent in the environment, potentially finding their way into water supplies.

The research, which is available online and will be featured on the cover of Reproductive Toxicology (Volume 30, Issue 4), found that the incidence of prostate inflammation went from 48 percent in the control group to 81 percent in the male offspring who were exposed to a mixture of atrazine and its breakdown products prenatally. The severity of the inflammation increased with the strength of the doses. Puberty was also delayed in the animals who received atrazine.

The doses of atrazine mixture given to the rats during the last five days of their pregnancy are close to the regulated levels in drinking water sources. The current maximum contamination level of atrazine allowed in drinking water is 3 parts per billion. The doses given to the animals were 0.09 (or 2.5 parts per million), 0.87, or 8.73 milligrams per kilogram body weight.

The research was led by Suzanne Fenton, Ph.D., and Jason Stanko, Ph.D., of the National Institute of Environmental Health Sciences (NIEHS), part of the National Institutes of Health. Fenton began the work as a researcher at the United States Environmental Protection Agency (EPA), but completed the research at NIEHS, working closely with NIEHS pathologists. Both NIEHS and EPA provided financial support for the study.

"We didn't expect to see these kinds of effects at such low levels," Fenton said. She adds that this is the second paper to show low dose effects of atrazine metabolite m
'/>"/>

Contact: Robin Mackar
rmackar@niehs.nih.gov
919-541-0073
NIH/National Institute of Environmental Health Sciences
Source:Eurekalert

Page: 1 2

Related biology news :

1. Pesticide atrazine can turn male frogs into females
2. Atrazine is the main weapon against weeds in sweet corn, with few alternatives
3. What causes cell defenses to crumble?
4. Mercury pollution causes immune damage to harbor seals
5. Stomach ulcer bug causes bad breath
6. St. Jude identifies genomic causes of a certain type of leukemia relapse
7. Lack of vitamin D causes weight gain and stunts growth in girls
8. Irritable bowel syndrome can have genetic causes
9. New tool could unpick complex cancer causes and help sociologists mine Facebook
10. MU researcher identifies possible genetic causes of borderline personality disorder
11. Genetic mutation causes familial susceptibility for degenerative brain disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/12/2015)... Calif. , Aug. 12, 2015  Synaptics ... of human interface solutions, today announced that four ... announced Match-in-Sensor solution, have officially been named FIDO ... As part of the certification, Synaptics, Natural ID™ ... 1.0 Universal Authentication Framework (UAF) standard and are ...
(Date:8/6/2015)... 2015  Today, U.S. Congressman Mike Honda ... to learn firsthand how Silicon Valley technologies can ... a world leader in multi-factor identity management and ... federal agencies and commercial organizations achieve new levels ... "The vast majority of network breaches can be ...
(Date:8/5/2015)... ALBANY, New York , August 5, 2015 /PRNewswire/ ... new market report titled "Facial Recognition Market - Global ... - 2022", the global market for facial recognition is ... market is driven by increased demand for surveillance systems ... to the rising number of crimes and terrorist activities ...
Breaking Biology News(10 mins):Synaptics Announces FIDO Certification of Natural ID Fingerprint Solutions 2Synaptics Announces FIDO Certification of Natural ID Fingerprint Solutions 3Rep. Honda to Visit Crossmatch in Redwood City 2Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 2Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 3Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 4Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 5Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 6
... Deep red tomatoes get their rich color from lycopene, ... a special variety of orange-colored tomatoes provide a different ... readily use. , Researchers found that eating spaghetti covered ... tomatoes, caused a noticeable boost in this form of ...
... children's game participants stand as close as possible without ... be very, very close without actually touching one another ... biologists. , Now MIT researchers led by Sangeeta Bhatia, ... the Harvard-MIT Division of Health Sciences and Technology (HST) ...
... have identified how different species use common genes to ... are used to accommodate their own features. The findings, ... and Steve Small’s laboratories in NYU’s Center for Developmental ... pathways across species. The study is published in the ...
Cached Biology News:Unique tomatoes tops in disease-fighting antioxidants 2Unique tomatoes tops in disease-fighting antioxidants 3MIT device draws cells close -- but not too close -- together 2MIT device draws cells close -- but not too close -- together 3NYU scientists identify how development of different species uses same genes with distinct features 2
(Date:8/27/2015)... Aug. 27, 2015 HUYA Bioscience International (HUYA) today ... the Japan Society of HTLV-1, held this week at ... purpose of the Society is to promote research on ... of medical technology and research related to these fields ... "HUYA is proud to support this prestigious conference," ...
(Date:8/27/2015)... (PRWEB) , ... August 27, 2015 , ... ... Personalized Medicine, recently presented new data on the relationship of genetics and hypertension ... World Congress on Heart Disease in Vancouver, British Columbia, Canada. The event, which ...
(Date:8/26/2015)... -- The Diabetes Research Institute (DRI), a Center of ... of Medicine, announced today that the first patient ... first time a novel transplant technique for insulin-producing ... I/II study builds upon decades of progress in ... step toward the development of the DRI BioHub, ...
(Date:8/26/2015)... August 26, 2015 After litigating and ... NV relating to P2i United States ... dispute in the United States without ... part of either party. As a result of the parties, ... California dismissed the case without prejudice. ...
Breaking Biology Technology:HUYA Bioscience International Sponsors Japan Society Of HTLV-1 Annual Meeting 2HUYA Bioscience International Sponsors Japan Society Of HTLV-1 Annual Meeting 3HUYA Bioscience International Sponsors Japan Society Of HTLV-1 Annual Meeting 4Proove Biosciences Presents Ground-Breaking Data on Genetics and Heart Disease at 20th World Congress on Heart Disease 2Proove Biosciences Presents Ground-Breaking Data on Genetics and Heart Disease at 20th World Congress on Heart Disease 3Diabetes Research Institute Successfully Transplants First Patient In Pilot BioHub Trial 2Diabetes Research Institute Successfully Transplants First Patient In Pilot BioHub Trial 3Diabetes Research Institute Successfully Transplants First Patient In Pilot BioHub Trial 4P2i Settles United States Litigation 2
... 4 /PRNewswire-Asia-FirstCall/ -- Mindray Medical,International Limited (NYSE: ... of medical devices worldwide announced today its selected ... year ended December 31, 2008.,The financial results reported ... monitoring business acquired from Datascope ("DPM") starting from ...
... a 7% increase over last year,s first , quarter , ... Record pre-tax income of $15.4 million , - Earnings per share ... first quarter , - New products launched containing life,sDHA(TM) in ... in gross margin continue to demonstrate the strong , ...
... 4 The Healthcare practice at Frost ... 2009 Quarterly Analyst Briefing Presentation on the North ... March 5, 2009 at 10:00 a.m. PST. (Logo: ... growth and is experiencing several notable trends, such ...
Cached Biology Technology:Mindray Announces 2008 Fourth Quarter and Full Year Results 2Mindray Announces 2008 Fourth Quarter and Full Year Results 3Mindray Announces 2008 Fourth Quarter and Full Year Results 4Mindray Announces 2008 Fourth Quarter and Full Year Results 5Mindray Announces 2008 Fourth Quarter and Full Year Results 6Mindray Announces 2008 Fourth Quarter and Full Year Results 7Mindray Announces 2008 Fourth Quarter and Full Year Results 8Mindray Announces 2008 Fourth Quarter and Full Year Results 9Mindray Announces 2008 Fourth Quarter and Full Year Results 10Mindray Announces 2008 Fourth Quarter and Full Year Results 11Mindray Announces 2008 Fourth Quarter and Full Year Results 12Mindray Announces 2008 Fourth Quarter and Full Year Results 13Mindray Announces 2008 Fourth Quarter and Full Year Results 14Mindray Announces 2008 Fourth Quarter and Full Year Results 15Mindray Announces 2008 Fourth Quarter and Full Year Results 16Mindray Announces 2008 Fourth Quarter and Full Year Results 17Mindray Announces 2008 Fourth Quarter and Full Year Results 18Mindray Announces 2008 Fourth Quarter and Full Year Results 19Martek Announces First Quarter 2009 Financial Results 2Martek Announces First Quarter 2009 Financial Results 3Martek Announces First Quarter 2009 Financial Results 4Martek Announces First Quarter 2009 Financial Results 5Martek Announces First Quarter 2009 Financial Results 6Martek Announces First Quarter 2009 Financial Results 7Martek Announces First Quarter 2009 Financial Results 8Martek Announces First Quarter 2009 Financial Results 9Martek Announces First Quarter 2009 Financial Results 10Frost & Sullivan's Biopharmaceuticals Market Briefing to Address the Use of Embryonic Stem Cells 2
... Reagent, 1 ml. Improves reproducibility ... by preventing streaking.Eliminates extra spots ... proteins.Stabilizes proteins throughout entire 2-D ... protein patterns.Ideal for both analytical ...
... offers major advantages over other RNA precipitation methods ... or carbohydrates. It is the method of choice ... from RNA preparations. Note, LiCl precipitation may not ... If the RNA is to be used for ...
LIVE/DEAD® Sperm Viability Kit *200-1000 assays*...
Human Xg Affinity Purified Polyclonal Ab Keywords: Xg glycoprotein, hereditary hemorrhagic telangiectasia Protein Family: ...
Biology Products: