Navigation Links
'At home' genomic tests for disease risk premature
Date:3/18/2008

NEW YORK, MARCH 18, 2008--The recent marketing of at home genomic tests for disease risk may be premature, according to Dr. Kenneth Offit, MD, MPH, Chief of the Clinical Genetics Service at Memorial Sloan-Kettering Cancer Center (MSKCC). Health professionals are now faced with the prospect of their patients coming to the office, a DNA profile in hand, asking for preventative management tailored to their specific disease risks, Dr. Offit writes in the March 19 special genomics issue of the Journal of the American Medical Association (JAMA).

In recent years, more than two dozen companies have been marketing a range of genetic tests directly to consumers concerned about genetic conditions. These conditions include those related to risks for disease, other genetic traits, and ancestry. Some of these companies have marketed whole genome scans, which provide assessments of risk for various health conditions ranging from the type of earwax an individual forms to his or her risks for diseases including cancer, diabetes, and blindness.

In his JAMA commentary, Dr Offit offers several caveats and recommendations to help doctors and counselors as they consider offering these research-based tests in clinical practice. Dr Offit voices concerns about the scientific accuracy of some of these tests, because they have not yet been validated in forward looking (prospective) clinical studies. In addition, he writes, the laboratory accuracy of these tests may vary.

A second concern voiced in the commentary is the direct to consumer aspect of the marketing of these tests, which excludes guidance from healthcare professionals. According to Dr. Offit, this limits the sources of information available to consumers about these tests and their accuracy from those marketing the tests. This critical lack of information, he says, raises concerns that patients/individuals may not have the resources to make unbiased decisions regarding whether to proceed with genetic testing.


'/>"/>

Contact: Jeanne D'Agostino
DAgostiJ@mskcc.org
212-639-3573
Memorial Sloan-Kettering Cancer Center
Source:Eurekalert

Page: 1 2

Related biology news :

1. Fireproofing homes dramatically reduces forest fire size, according to new study
2. Homeland Security awards 2 grants to Rutgers for nuclear threat detection
3. Saltwater crocodiles can find their way home
4. Zinc may reduce pneumonia risk in nursing home elderly
5. The surprising story of Charles Darwin and his homeopathic doctor
6. Threatened bird species finds home at Western
7. Chemist Brings SAFETY Act Expertise to Homeland Security Firm
8. Selective restraints and reduced medication could reduce nursing home falls says 4-year study
9. How baby fish find a home
10. Opening day for a home of the future
11. Increased allergen levels in homes linked to asthma
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... that under the normal circumstances, astrocytes participate ... neuronal environment, and exhibit therapeutic and repairing ... Previous studies have found that nerve cells ... induction have reduced viability, which produces influences ... Yuan, Kailuan General Hospital, Hebei United University, ...
(Date:7/11/2014)... Rio de Janeiro, Brazil- In the brains of ... mechanism that allows an electric or chemical signal ... another. Chemical synapses, which are the most abundant ... inhibitory. Synapse formation is crucial for learning, memory, ... and inhibitory synapses critical for brain function. ...
(Date:7/10/2014)...  Aware, Inc. (NASDAQ: AWRE ), a ... on June 26, 2014 that its Board of Directors ... share, or approximately $40 million in total.  The Board ... a payment date of July 24, 2014.  The Company ... an ex-dividend date for this special cash dividend.  An ...
Breaking Biology News(10 mins):Blame it on the astrocytes 2NASDAQ Sets Ex-Dividend Date for Aware, Inc.'s Special Cash Dividend of $1.75 Per Share 2
... President and Scientific Director and Director of the Hematopoiesis ... cliniques de Montral (IRCM), and his team was recently ... the American Society of Hematology. The researchers found that ... cells, which could lead to a better treatment for ...
... University of California, Riverside Bourns College of Engineering ... recently awarded a five-year, $6.25 million grant to ... for soldiers increasingly reliant on electronic devices. ... department of environmental and chemical engineering, and researchers ...
... Amid growing concern that synthetic life sciences pose biosecurity ... DNA sequence trade. Research published today in the ... looks at the necessity of a global regulator for ... Synthetic life sciences are making breakthroughs at a ...
Cached Biology News:A scientific breakthrough could be the first step in a better treatment for leukemia patients 2Research aims to lighten load carried by soldiers 2Technology to screen for synbio abuses lags 2Technology to screen for synbio abuses lags 3
(Date:7/10/2014)... OMICS Group’s 5th International conference and ... 2014 at Double Tree by Hilton Beijing, China is ... Analytical & Bioanalytical research methods only to facilitate improved ... occasion, Dr. Srinubabu Gedela, MD of OMICS Group Inc ... remarkable one in bringing a unique and international mix ...
(Date:7/10/2014)... Senior supply chain management executives from over ... challenges of “Reducing Cost, Lead Time, & Defects in ... Describing the partnership of the Bio Supply Management Alliance ... ( SCMI) of the University of San Diego ... Kroc Institute of Peace and Justice in San Diego, ...
(Date:7/10/2014)... , July 10, 2014 On ... Dmitry Medvedev , presented Russia,s ... BIOCAD . The Company is developing a unique project ... project BIOCAD develops a number of innovative drugs based ... diseases. The ceremony took place at the International Exhibition ...
(Date:7/10/2014)... , July 10, 2014 /PRNewswire-iReach/ -- ... and interpretation, today announced an agreement with ... analytics for Lineagen,s NextStep Dx PLUS.  ... neurodevelopmental and neurological disorders, currently offers FirstStep ... (CMA) testing service used by healthcare providers ...
Breaking Biology Technology:A Critical Review of Analytical Techniques for Improved Living Standards 2A Critical Review of Analytical Techniques for Improved Living Standards 3A Critical Review of Analytical Techniques for Improved Living Standards 4Biotech & Biopharm Supply Chain Management Executives Launch BSMA in San Diego 2Biotech & Biopharm Supply Chain Management Executives Launch BSMA in San Diego 3Biotech & Biopharm Supply Chain Management Executives Launch BSMA in San Diego 4Dmitry Medvedev Presented BIOCAD the First National "Industry" Award 2Tute Genomics Platform Selected to Provide Clinical Interpretation for Lineagen's NextStepDx PLUS Next-Generation Sequencing-Based Diagnostic Test 2Tute Genomics Platform Selected to Provide Clinical Interpretation for Lineagen's NextStepDx PLUS Next-Generation Sequencing-Based Diagnostic Test 3Tute Genomics Platform Selected to Provide Clinical Interpretation for Lineagen's NextStepDx PLUS Next-Generation Sequencing-Based Diagnostic Test 4
... somehow survived where other traditional marketing tools and old ... must face harsher realities once again, all to ensure ... Web sites are simply doomed. While billions of Web ... clash into the billions of surfing customers and simply ...
... Ted Kanavas, R-Brookfield, called on the Legislature and the ... Development Fund. , ,The fund would use existing information ... Administration and segregate a portion of the funds for ... would not flow into this fund. , ,This fund ...
... Corporation and First Data Corporation jointly ... provides for the purchase of substantially all of the ... approximately $610 million in cash. As the majority shareholder ... million and NYCE will become a Metavante subsidiary. , ...
Cached Biology Technology:The mysteries and the future of Web sites 2The mysteries and the future of Web sites 3The mysteries and the future of Web sites 4Metavante and First Data to buy PIN-debit company NYCE 2