Navigation Links
At Boston symposium, NARSAD researchers report on genes and family traits
Date:6/3/2008

come with troubling side effects, such as sleep changes, sexual problems, headaches and gastrointestinal problems, and an analysis by the Food and Drug Administration has shown that antidepressants may cause suicidal thinking and behavior in children, adolescents and adults ages 18 to 24.

According to Roy Perlis, M.D., M.Sc., the director of pharmacogenomics research at Massachusetts General Hospital's Department of Psychiatry, specific genes may influence how individual patients respond to antidepressant therapies, which is why his research team is using NARSAD funds to try to find these genes.

After studies in mice identified variations of four genes that may affect how individuals respond to antidepressant treatment, Dr. Perlis and his colleagues examined these four genes in DNA samples provided by 1,554 people participating in a large government study called the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) trial. What the team found was a link between a variation in the gene TREK1 and poorer response to antidepressant treatment. This is especially significant because people with depression often require more than one treatment before they find one that "works" for them. If individuals with more "treatment-resistant" depression can be identified early in their illness, they may be treated more effectively. Further, Dr. Perlis believes that studying how variations in genes affect response to medications will also lead to a completely new class of more targeted antidepressant therapies.

"Our hope is that one day, we will be able to match patients to those treatments that are most likely to be effective," Dr. Perlis noted. "When we understand how people respond to different treatments and why, we will be able to design more targeted therapies for depression."

Family Traits Provide Clues to Genes for Schizophrenia, Bipolar Disorder

It is also important to identify the endophenotypes -- traits ass
'/>"/>

Contact: Kristen Simone
ksimone@narsad.org
516-829-0091
NARSAD, The Mental Health Research Association
Source:Eurekalert

Page: 1 2 3 4 5 6

Related biology news :

1. Software developed by Boston College lab delivers speed and accuracy to genome research
2. Singapores BIOPOLIS and FUSIONOPOLIS on stage in Boston this week
3. DHS Begins Collecting 10 Fingerprints From International Visitors at Boston Logan International Airport
4. Boston College profs study oxidative stress subcellular to discover its role in diseases
5. Boston University biomedical engineers find chink in bacterias armor
6. Rockefeller University hosts 2-day evolution symposium, May 1-2, 2008
7. Pioneers in small RNA research to present at UD symposium, April 16
8. NARSAD presents 2007 prizes for outstanding achievement in neuroscience and psychiatric research
9. Fruits, vegetables and teas may protect smokers from lung cancer, UCLA researchers report
10. 2 University of Illinois researchers named HHMI investigators
11. New family of gecko discovered by researchers from the U of Minnesota and Villanova University
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... be cheerful, happy-go-lucky characters, so you might expect that ... , In fact some dogs are distinctly more pessimistic ... , "This research is exciting because it measures ... non-invasively. It offers researchers and dog owners an insight ... said Dr Melissa Starling, from the Faculty of Veterinary ...
(Date:9/18/2014)... are too stressed they are often grouchy, grumpy, nasty, ... (BMI) at EPFL have just highlighted a fundamental synaptic ... the loss of social skills and cognitive impairment. When ... molecule in the brain. This was revealed by a ... Carmen Sandi,s team went to look for answers in ...
(Date:9/17/2014)... and affordable health care to reproductive technologies, the ... the ability of people to identify key issues, ... respectfully, and find the most defensible ways forward. ... support these societal conversations?, The Hastings Center and ... Issues have teamed up to publish a series ...
Breaking Biology News(10 mins):Dogs can be pessimists too 2Dogs can be pessimists too 3How stress tears us apart 2Why bioethics literacy matters 2Why bioethics literacy matters 3
... America (ESA) is proud to announce the winners ... travel grants, which will help entomology students attend ... this November are funded by USDA-NIFA,s Agriculture ... and Nematodes. The grants were created to provide ...
... predicted that tree species will respond to global warming ... a new study of 65 different species in 31 ... Nearly 80 percent of the species aren,t yet ... staying in place -- but speeding up their life ...
... Children,s Hospital Medical Center has developed an antibody that ... hospitalized patients who receive central lines. Margaret Hostetter, ... her team developed the antibody, which prevents Candida ... formation of biofilm in a rat model of catheter-associated ...
Cached Biology News:Entomological Society of America names winners of 2013 student travel grants 2Entomological Society of America names winners of 2013 student travel grants 3Entomological Society of America names winners of 2013 student travel grants 4Entomological Society of America names winners of 2013 student travel grants 5Entomological Society of America names winners of 2013 student travel grants 6Entomological Society of America names winners of 2013 student travel grants 7Entomological Society of America names winners of 2013 student travel grants 8Climate change may speed up forests' life cycles 2
(Date:9/19/2014)...  InterMune, Inc. (Nasdaq: ITMN ) today ... to settle the litigation in the Delaware Court of ... dated as of August 22, 2014, among Roche Holdings, ... term of the Memorandum of Understanding, the Company agreed ... attached exhibit reflecting the amendment to the Company,s Schedule ...
(Date:9/19/2014)... 2014  An entire month is dedicated to one ... Charcot-Marie-Tooth disease (CMT) – a debilitating neuromuscular disease affecting ... atrophy, weakness, and foot and hand deformities. CMT affects ... CMT is a progressive disease, and over time patients ... devices such as leg braces, wheelchairs and scooters to ...
(Date:9/19/2014)... Barnhardt Manufacturing Company has earned the ... Cotton . The USDA Certified Biobased Product Label verifies ... or exceeds levels set by USDA. Biobased products are ... significant part of agricultural, forestry, or marine ingredients. ... be immediately identified as a USDA certified BioPreferred ...
(Date:9/18/2014)... Bipartisan passage this week by the ... stimulate development and commercialization of new technologies and promote ... of SPIE, the international society for optics and ... Innovation (RAMI) Act, now moves to the full Senate ... are optimistic that it will win passage there as ...
Breaking Biology Technology:InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 2InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 3InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 4InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 5InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 6InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 7InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 8InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 9InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 10InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 11InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 12InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 13InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 14InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 15InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 16InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 17InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 18InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 19September is Charcot-Marie-Tooth (CMT) Awareness Month - Scheduled events, activities and important partnerships announced throughout the month! 2Barnhardt Manufacturing Company Earns USDA Certified Biobased Product Certification and Label for Organic Cotton 2House passage of high-tech manufacturing bill is move toward stronger economy, say SPIE leaders 2House passage of high-tech manufacturing bill is move toward stronger economy, say SPIE leaders 3
...  inVentiv Health, Inc., offering best-in-class clinical, commercial and ... it has completed the acquisition of Kforce Clinical ... solutions to pharmaceutical, biotech and medical device companies, ... The transaction closed on March 30, 2012.  ...
... 3, 2012 Health Diagnostic Laboratory, Inc. (HDL, Inc.), ... of Scott Blackwell. Recently named Vice President of Corporate ... values of an advanced laboratory that is growing on ... http://photos.prnewswire.com/prnh/20120403/PH81634 )  "Scott comes to our ...
... N.J., April 3, 2012 Hamamatsu Corporation announces ... distributed through third-party dealers, will now be available ... the company is responsible for the sales, marketing, ... product line for new customers throughout North America. ...
Cached Biology Technology:inVentiv Health Completes Acquisition of Kforce Clinical Research 2inVentiv Health Completes Acquisition of Kforce Clinical Research 3inVentiv Health Completes Acquisition of Kforce Clinical Research 4Health Diagnostic Laboratory Names Scott Blackwell Vice President of Corporate Culture 2Hamamatsu Corporation Announces Exclusive Distribution of Its NanoZoomer Whole-Slide Scanners 2
... binding specificity and signaling of the members ... be modified by alternative splicing--which has important ... you can perform a classical expression profiling ... different alternatively spliced forms of the gene ...
Mouse monoclonal antibody raised against a partial recombinant ST3GAL2. NCBI Entrez Gene ID = ST3GAL2...
... Extraction Kit is manufactured for DNA purification ... byexposure to UV light. The Purification of ... used for DNA-cloning work. The conventional method ... exposure of UV light damages DNA and ...
CleanBox DNA workstation with two 254nm UV lambs & 12-hr timer, 90cm (36-inch)width, single door, 115V (w/crating)...
Biology Products: