Navigation Links
Astronomy technology brings nanoparticle probes into sharper focus
Date:2/19/2008

ATLANTA (February 19, 2008) While pondering the challenges of distinguishing one nano-sized probe image from another in a mass of hundreds or thousands of nanoprobes, researchers at Georgia Tech and Emory University made an interesting observation. The tiny, clustered dots of light looked a lot like a starry sky on a clear night.

The biomedical researchers realized that astronomers had already made great strides in solving a problem very similar to their own isolating and analyzing one dot (in this case a star) in a crowded field of light. They hypothesized that a computer system designed for stellar photometry, a branch of astronomy focused on measuring the brightness of stars, could hold the solution to their problem.

Now, Georgia Tech and Emory researchers have created a technology based on stellar photometry software that provides more precise images of single molecules tagged with nanoprobes, particles specially designed to bind with a certain type of cell or molecule and illuminate when the target is found. The clearer images allow researchers to collect more detailed information about a single molecule, such as how the molecule is binding in a gene sequence, taking scientists a few steps closer to truly personalized and predictive medicine as well as more complex biomolecular structural mapping.

In addition to biomedical applications, the system could be used to clarify other types of nanoparticle probes, including tagged particles or molecules.

The research is detailed in this week's online Early Edition of the Proceedings of the National Academy of Sciences (PNAS).

As more powerful imaging technologies are developed, scientists face a real challenge to quantitatively analyze and interpret these new mountains of data, said May Wang, an assistant professor in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University. This PNAS paper is only a start, but I expect that in
'/>"/>

Contact: Megan McRainey
megan.mcrainey@comm.gatech.edu
404-894-6016
Georgia Institute of Technology
Source:Eurekalert

0

GOOD

Page: 1 2 3

Related biology news :

1. Strategy for nanotechnology-related environmental, health and safety research
2. New technology sharpens X-ray vision
3. Iridescence workshop promotes natures nanotechnology
4. Department of Energy putting power in the hands of consumers through technology
5. Bangladesh to dramatically expand technology that doubles efficiency of urea fertilizer use
6. Cheaper drugs now closer to realization with new DropArray technology
7. New report finds great potential for Swedish medical technology
8. Breakthrough technology observes synapse in real time, supporting theory of vesicular recycling
9. FDLI, PEN co-sponsor major conference on nanotechnology
10. CU-Boulder technology used to identify unexpected bacteria in cystic fibrosis patients
11. Using nanotechnology, UCLA researchers discover cancer cells feel much softer than normal cells

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/24/2009)... NEW YORK (November 24, 2009) -- The Wildlif...ort revealing that the last remaining population o...y due to the rising tide of poaching and habitat l... inform Russian officials of what needs to be done...iggest cat. , The report was releas...
(Date:11/24/2009)..., Md. (November 24, 2009) New research on bacteri...cosystems reveals predictable temporal patterns, s...ies as markers for monitoring climate change in th... the Proceedings of the National Academy of Scien...es in the six rivers shifted synchronously over ti...
(Date:11/23/2009)...n, D.C. The community-associated strain of the de...sistant to most common antibioticsposes a far grea...ing its way into hospitals, according to a study i...ses . , The new threat is easily picked up in f...nd has increased the overall burden of MRSA within...
Breaking Biology News(10 mins):Report shows dramatic decline in Siberian tigers 2Researchers establish common seasonal pattern among bacterial communities in Arctic rivers 2New study finds MRSA on the rise in hospital outpatients 2Genes May Link Hip Fractures and Heart Disease 59850 1Genes May Link Hip Fractures and Heart Disease 59850 2Genes May Link Hip Fractures and Heart Disease 59850 3Experimental treatments restore partial vision to blind people 10444 1Experimental treatments restore partial vision to blind people 10444 2Genomes of 2 popular research strains of E coli sequenced 10441 1Genomes of 2 popular research strains of E coli sequenced 10441 2Genomes of 2 popular research strains of E coli sequenced 10441 3
... , Biologists at the University of California, San...e morning and evening components of the daily biol...ed in the March 13 issue of Science , solves a lo... mechanisms that control plant clocks and could pr...f agricultural crops. , The finding is the first ...
... Philadelphia (March 18, 2009) As any parent kno...esearch from the University of Washington and the ...g for sweetness has a biological basis and is rela...onship between sweet preference and growth makes i...ic demands increase. Children are programmed to l...
... Being satisfied with one,s appearance is one of ...lf image. However, in today,s appearance culture i...ren and young people are dissatisfied with their a...ect to bullying are particularly critical of their...long period. This is revealed in a new thesis in p...
Other Biology News:Missing piece of plant clock found 2Liking sweets makes sense for kids 2Children who are dissatisfied with their appearance often have problems with their peer group 2
(Date:11/25/2009)...re/ -- Biotech firm Replikins Ltd., which has anal...ndemic through the prediction, outbreak, and progr... latest biochemical analysis of the virus. The new... Flu") virus has dropped from its peak of 3.7 (s.d...spring of 2009 to resting non-epidemic levels this...
(Date:11/25/2009)...Newswire-Asia/ -- Sinovac Biotech Ltd. ( SVA),a l...ed today that it executed,a joint venture (JV) agr...ology Co., Ltd. (Sinovac Dalian). The JV will rese... vaccines. Sinovac will contribute its expertise,a...rld-class vaccines; the,other party will bring its...
(Date:11/24/2009)...e-FirstCall/ -- IES (Nasdaq: IESC ), a leading na...ystems and services for the commercial, industrial... commercial business group has been awarded a cont...rical systems for the Level 4 bio-safety lab (BSL-...esearch Institute of Infectious Diseases (USAMRIID...
(Date:11/24/2009)...Nov. 24 Dow AgroSciences... of Hyland Seeds, a division of Thompsons Limited ... will further expand Dow AgroSciences, current see...ction of SmartStax(TM) in 2010 and Dow AgroS...n in 2012. The transactional close is expected in ...
Breaking Biology Technology:Biological H1N1 Vaccines: Too Little, Too Late 2Biological H1N1 Vaccines: Too Little, Too Late 3Biological H1N1 Vaccines: Too Little, Too Late 4Biological H1N1 Vaccines: Too Little, Too Late 5Sinovac Establishes Joint Venture to Expand Human-Use Vaccine Development and Manufacturing Capabilities 2Sinovac Establishes Joint Venture to Expand Human-Use Vaccine Development and Manufacturing Capabilities 3Integrated Electrical Services Awarded Contract to Provide Electrical Systems for U.S. Army Medical Research Institute of Infectious Diseases 2Dow AgroSciences Canada Announces Agreement to Acquire Hyland Seeds 2Dow AgroSciences Canada Announces Agreement to Acquire Hyland Seeds 3
... Revenue of $88 to $90 Million and Net Income of $... HARBIN, China, Sept. 25 /Xinhua-PRNewswire-FirstC...e Medical" or "the Company") (Nasdaq: CSKI ), a,l...ducing over-the-counter,drugs in the People,s Repu... increased its revenue and earnings guidance for t...
...Sept. 25 Bion Environmental Technologies,Inc. (OT...n was received,today that its patent application e...ystem" has been granted by the Commonwealth of Aus...umber of 2002227224. The,official filing date is a...,in force until an expiration date of November 8, ...
... N.J., Sept. 25 Osteotech, Inc.,(Nasdaq: OSTE ),...ons for,regenerative medicine, announced today the...its Board of Directors. Dr. Laurencin joined the,B... will serve on both the,Audit and the Compensation.... Fallon, III, Chairman of the Board of Directors,...
Other Biology Technology:China Sky One Medical, Inc. Raises Guidance for 2008 Revenue and Net Income 2China Sky One Medical, Inc. Raises Guidance for 2008 Revenue and Net Income 3Bion Announces Approval of New Australian Patent for Low Oxygen Organic Waste Bioconversion for Livestock Waste Environmental Treatment 2Cato T. Laurencin, M.D., Ph.D. to Join Osteotech Board of Directors 2
...d 36kDa (C) subunits Formulation: 10% glycerol, 20...l, 1mM MgCl2, 1mM EGTA, 0.1mM MnCl2 1mM DTT, and 0... vitro dephosphorylation of proteins. Purification...filtration chromatography Quality Assurance: routi...
...acellular Localization Kit provides a straight for... of your design, in an efficient yet non-destructi...ellular localization and functional inhibition of ...introduction of the labeled siRNA into mammalian c...
...acellular Localization Kit with TransIT-siQUEST Tr...roach to directly label and deliver siRNA, of your...r, for in vitro tracking experiments. Subcellular ...ene expression can be monitored following introduc...
...eproducible immunoprecipitation (IP) by using a 96...e than regular IPs, which are problematic with reg...srupting the agarose bed. The binding of the antib...ible, and elution of the immune complex can occur ...
Biology Products: