Navigation Links
As rates rise, researchers find better way to identify melanoma
Date:7/17/2008

University of Rochester Medical Center researchers found a new protein produced excessively in malignant melanoma, a discovery that is particularly relevant as skin cancer rates climb dramatically among young women.

The protein, IMP-3, is not over-expressed in harmless moles but is increased in the most dangerous types of skin cancer, and in a subset of lesions that can be difficult to predict called thin melanomas. The finding offers a potential target for treatment but perhaps most importantly might give doctors a new, objective way to distinguish melanoma from some benign moles that look like melanoma but are not cancerous.

"We are very excited about our finding that IMP-3 is an important progression marker in malignant melanoma," said first author Jennifer G. Pryor, M.D., a third-year resident in the URMC Department of Pathology and Laboratory Medicine. "Although we have learned a lot about melanoma in recent years, it has unique biologic properties that sometimes make it difficult to diagnose and to plan for the proper treatment. This protein may have a key role in helping us to understand and distinguish between various types of melanocytic lesions."

The research is published in the journal Modern Pathology. http://www.nature.com/modpathol/journal/v21/n4/full/3801016a.html

This summer the National Cancer Institute warned that new cases of melanoma among young women jumped 50 percent since 1980. Possible explanations, medical experts said, include increased use of tanning beds and more time spent outdoors. Overall rates of melanoma have also been rising among older adults.

The pilot study investigated samples of 56 biopsied lesions from 48 adults. The lesions fell into the category of cutaneous melanocytic neoplasms, a diverse group that includes benign moles; Spitz nevi, a type of mole seen in younger people that can be ea
'/>"/>

Contact: Leslie Orr
Leslie_Orr@urmc.rochester.edu
585-275-5774
University of Rochester Medical Center
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Spotted hyenas can increase survival rates by hunting alone
2. Colorectal cancer screening rates still too low
3. Species have come and gone at different rates than previously believed
4. Scientists find 245 million-year-old burrows of land vertebrates in Antarctica
5. Forest canopies help determine natural fertilization rates
6. Boffinry and Baftas: Brothers double doctorates
7. Nitrates in vegetables protect against gastric ulcers
8. Sonic Innovations Celebrates 10-Year Anniversary
9. Herceptin and chemo improves response rates without major adverse effects in HER2 breast cancer
10. Autism Speaks collaborates on grant with the Allen Institute for Brain Science and autism expert
11. bioMETRX Incorporates OKIs Fingerprint Engine in its smartTOUCH Product Line
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/19/2014)... household electricity access in India over the last ... total carbon emissions growth during that time, according ... Nature Climate Change ., "Energy access is ... aspects of life, including education, communication, and health," ... study. , While increased energy access is widely ...
(Date:10/17/2014)... knowledge regarding Ebola is critical and pertinent for practicing ... global outbreak and epidemic. The Journal, Disaster Medicine ... issue, Ebola Virus and Public Health, to surround the ... this critical societal moment. , On October 17, ... Clinicians . The primer was prepared by Dr. Eric ...
(Date:10/16/2014)... constantly wages war on the human body. Battles ... stalemate. In pancreatic cancer, this stalemate—known as tumor ... aggressively malignant, a phenomena that is poorly understood. ... the laboratory of Salvatore Torquato, a Professor of ... conditions surrounding tumor dormancy and the switch to ...
Breaking Biology News(10 mins):Improved electricity access has little impact on climate change 2Modeling tumor dormancy 2
... For the first time in nearly 50 years, ... rediscovered in the San Bernardino National Forest,s San Jacinto ... suitability of sites to re-establish frogs and scientists from ... natural history expedition both rediscovered the rare mountain yellow-legged ...
... , VILNIUS, Lithuania, July 27 ... identification technologies provider, announced today their inclusion as the core ... Issuance System. MegaMatcher SDK multi-biometric technology ... PT. Berca Hardayaperkasa, to develop a distributed passport ...
... - Temperature explains much of why cold-blooded organisms ... at higher latitudes than at lower latitudes, according to ... the National Academy of Sciences ( PNAS ) ... Santiago Salinas, both of Stony Brook University,s School of ...
Cached Biology News:Biologists rediscover endangered frog population 2Biologists rediscover endangered frog population 3Biologists rediscover endangered frog population 4Indonesia Now Using MegaMatcher Biometric Technology in Integrated Passport Issuance System 2Indonesia Now Using MegaMatcher Biometric Technology in Integrated Passport Issuance System 3Indonesia Now Using MegaMatcher Biometric Technology in Integrated Passport Issuance System 4Warmer environment means shorter lives for cold-blooded animals 2
(Date:10/20/2014)... , A major pan-European survey into the ... care has revealed changing trends in many important GI ... of healthcare services across the continent. The results of ... (UEG), have been announced today and led to calls ... of GI disorders across Europe ...
(Date:10/20/2014)... N.J. (PRWEB) October 20, 2014 ... the Sidney Kimmel Cancer Center at Thomas Jefferson ... , Through the Strategic Alliance Partnership program, ... OncLive will collaborate to raise awareness of the ... treatment, and other projects. Clinicians and other health ...
(Date:10/19/2014)... The Latin American hardware encryption display market ... with analysis and forecast of revenue. This market was ... to reach $2,366.8 million by 2018, at a CAGR ... the TOC of the Latin American hardware encryption market ... provided. It also provides a glimpse of the segmentation ...
(Date:10/19/2014)... October 19, 2014 The Asia-Pacific ... market in Asia-Pacific with analysis and forecast of ... Asia Pacific Bromine Market report, to get an ... provides a glimpse of the segmentation in the ... tables and figures. , http://www.micromarketmonitor.com/market/asia-pacific-bromine-6741503144.html ...
Breaking Biology Technology:Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 2Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 3Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 4Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 5Sidney Kimmel Cancer Center at Thomas Jefferson University Partners With OncLive 2Sidney Kimmel Cancer Center at Thomas Jefferson University Partners With OncLive 3The Latin American hardware encryption display market is expected to reach $2,366.8 million by 2018 - New Report by MicroMarket Monitor 2The Latin American hardware encryption display market is expected to reach $2,366.8 million by 2018 - New Report by MicroMarket Monitor 3The Asia-Pacific Bromine Market is estimated to grow to $4,080.1 million by 2018 - New Report by MicroMarket Monitor 2The Asia-Pacific Bromine Market is estimated to grow to $4,080.1 million by 2018 - New Report by MicroMarket Monitor 3
... - The legal wheels still have some spinning to do, ... Foundation not owning three key stem cell patents, or ... decision by United States Patent and Trademark Office ... or modified, but for the first time since University ...
... - What's the penalty for software piracy? Six men who ... Automation software will soon find out as they await sentencing ... for illegally copying the software and selling it on the Internet ... article in the Milwaukee Journal Sentinel . , ,The ...
... presidential primaries less than a year away, campaigns are ... their party's voters. Interestingly, voters are using every available ... reach the polls. , ,This election cycle may be ... and other consumer-generated content. But sifting through all that ...
Cached Biology Technology:Is Wisconsin's stem cell standing diminished? 2Is Wisconsin's stem cell standing diminished? 3Is Wisconsin's stem cell standing diminished? 4Tired of the spin? ExpertVoter website makes candidate selection easier 2Tired of the spin? ExpertVoter website makes candidate selection easier 3
...
...
Immunogen: Peptide corresponding to amino acid residues from the N-terminal region of human thyroid hormone receptor, alpha1/alpha2-isotype. Storage: -20 C, Avoid Freeze/Thaw Cycles...
Antibodies were affinity purified using epitopes specific to QKI immobilized on solid support....
Biology Products: