Navigation Links
Artificial platelets could treat injured soldiers on the battlefield
Date:2/15/2013

olution to develop an antibody that could be attached to the hydrogels to cause their form to change when they encounter thrombin-activated fibrin. The resulting antibody has high affinity for the polymerized form of fibrin and low affinity for the precursor.

"We knew the molecule that we wanted and we knew the domains that were critical for recognition," Barker said. "The primary design concept was the ability to recognize an active, forming clot from the soluble, inactive precursor."

The artificial platelets have so far been tested in rats, and separately using in vitro simulated endothelial systems in the laboratory of Wilbur Lam, an assistant professor at Emory University in Atlanta. Though the work is a long way from a device that could be used on the battlefield, Barker envisions transitioning the research to a startup company that develop the technology to improve survivability for wounded soldiers.

"You could have it literally in the pocket of any soldier, who could pop it out when needed," Barker explained. "As the needle is extended, you would break the package of freeze-dried particles. The device would then be placed on the abdomen, where the particles would be injected into the bloodstream. They would circulate inactive until they encountered the initiation of clotting."

Once the bleeding was stopped, cytokines and anti-inflammatory compounds within the "designer" clot could help determine the phenotype that should be adopted by healing cells and regulate their behavior. That would set the stage for the subsequent healing process.

To help soldiers already suffering from the effects of fibrosis the contraction of scarred tissue the researchers are developing a polymer to which a natural peptide is attached. The peptide helps regulate the repair process that produces scars and could ultimately help reduce or reverse the effects of fibrosis. The technique has reversed the effects of pulmonary fibrosis in an a
'/>"/>

Contact: John Toon
jtoon@gatech.edu
404-894-6986
Georgia Institute of Technology
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. Artificial retina receives FDA approval
2. Artificial atoms allow for magnetic resonance on individual cells
3. Nanomaterials key to developing stronger artificial hearts
4. U. of Minn. researchers unveil first artificial enzyme created by evolution in a test tube
5. Cornell engineers solve a biological mystery and boost artificial intelligence
6. Scale-up of a temporary bioartificial liver support system described in BioResearch Open Access
7. New geometries: Researchers create new shapes of artificial microcompartments
8. High-speed video and artificial flowers shed light on mysteries of hummingbird-pollinated flowers
9. Researchers develop method to grow artificial tissues with embedded nanoscale sensors
10. Artificial intelligence helps detect subtle differences in mutant worms
11. UD partner in NIH research project to produce artificial salivary glands
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Artificial platelets could treat injured soldiers on the battlefield
(Date:8/20/2014)... athletes who have suffered concussions ready to return to ... that high school athletes who head back on the ... significant regression in their abilities to simultaneously walk and ... in changes in their balance and/or altered walking speed, ... the 12 had returned to activity in less than ...
(Date:8/20/2014)... pepper causes a burning spiciness that is irresistible to ... pepper,s effect are using their findings to develop a ... can be caused by inflammation or other problems. They ... tested in clinical trials, in ACS, Journal of ... that decades ago, scientists had pegged a compound called ...
(Date:8/20/2014)... plastic bags could one day be made out of ... are now reporting. The novel process they developed and ... its agricultural and plastic waste problems, appear in the ... S. Bayer and colleagues at the Italian Institute of ... In 2012, its production reached 288 million tons worldwide, ...
Breaking Biology News(10 mins):Recovery reversal seen in Oregon study of returning concussed athletes 2Recovery reversal seen in Oregon study of returning concussed athletes 3
... College-age football players who gain weight to add power to ... for diabetes and heart disease later in life, a new ... offensive and defensive linemen who underwent a battery of tests ... had at least three of five risk factors that indicate ...
... treatment of many common diseases such as diabetes and ... approach called systems biology, according to leading scientists from ... by the European Science Foundation, the scientists provide a ... medical research over the coming years. Systems biology ...
... world pay close attention to the state of the ... of scientific snow-watchers looking closely at a South Pole ... coordinated by the UK,s National Physical Laboratory (NPL) are ... the world,s largest inter-comparison between satellite sensors. ...
Cached Biology News:Athletes not spared from health risks of metabolic syndrome 2Athletes not spared from health risks of metabolic syndrome 3Key to future medical breakthroughs is systems biology, say leading European scientists 2Key to future medical breakthroughs is systems biology, say leading European scientists 3Satellites search out South Pole snowfields 2
(Date:8/20/2014)... NJ (PRWEB) August 20, 2014 WriteResult®, ... announced today that it has expanded its myPROpad™ ePRO ... the EQ-5D-5L, one of the most widely used ... measuring general health status. The EQ-5D is used during ... generate a measure that can be used to demonstrate ...
(Date:8/19/2014)... 2014 One of the major ... an inadequate vascular supply. Nutrient and gas transport ... is critical for successful regeneration and integration into ... deficiencies in vascularization and promote angiogenesis in a ... scaffold design and architecture, and enhancing scaffolds with ...
(Date:8/19/2014)... DUBLIN , Aug. 19, 2014 Research and ... Culture Supplies - Global Strategic Business Report" report to their ... Cell and Tissue Culture Supplies in US$ Thousands by the following ... separate comprehensive analytics for the US, Canada , ... Asia-Pacific , and Latin America . ...
(Date:8/19/2014)... IRVINE, Calif. (PRWEB) August 19, 2014 ... Indiegogo campaign to raise $200,000 to fund a ... diagnostic device. , This development is a ... one-size-fits-all model of care to the implementation of ... patient-centric method of practicing medicine. , Indiegogo contributions ...
Breaking Biology Technology:EQ-5D™ Assessment Now Available for iPad 2Vascularization in Tissue Engineering Highlighted at 12th New Jersey Symposium on Biomaterials Science 2Global Cell and Tissue Culture Supplies - Strategic Business Report 2014 2Cellgen Diagnostics Launches Indiegogo Crowdfunding Campaign for DNA Medical Testing Device 2Cellgen Diagnostics Launches Indiegogo Crowdfunding Campaign for DNA Medical Testing Device 3
... - The next generation of high-performance wireless communication ... at the University of Wisconsin-Madison . , ,But ... the country, pursuing a technology 14 years in the ... diamond and the tiny electromechanical systems into ...
... - Recently, as I sat at lunch sending off ... but reflect on how our professional lives continue to evolve ... ,As the CEO of a company that is driving the ... impressed with how quickly technological change continues to transform and ...
... high-tech startup and spin-off companies are gaining attention ... example of this is Primorigen Biosciences LLC ... for analysis of cellular reprogramming and differentiation. , ... and related products, will use a pair of ...
Cached Biology Technology:Nano-diamond film studied at UW could advance telecommunications 2Nano-diamond film studied at UW could advance telecommunications 3Visions: Rimas Buinevicius, CEO of Sonic Foundry 2Visions: Rimas Buinevicius, CEO of Sonic Foundry 3Wisconsin start up Primorigen Biosciences corrals out-of-state investment 2
... Chemicon Select Tissue Arrays are intended for ... tissues were fixed in neutral buffered formalin ... and diagnosis was performed by certified pathologists. ... paraffin blocks and relocated into a new ...
... adult normal Mega Western Protein Array was ... Mega Western Protein Arrays are manufactured using ... tissue sources. A protein sample from each ... with a Protein molecular weight marker on ...
... Proteomic Imaging System, Professional Package Superior ... Dynamic Range: The ProXPRESS 2D Proteomic Imaging ... system for both proteomic and general life ... flexibility, enabling the use of all dyes ...
... single use spatulas have been designed to ... are for those interested in eliminating the ... Each spatula is individually packaged, RNase/DNase free, ... is a new product number, created to ...
Biology Products: