Navigation Links
Artificial platelets could treat injured soldiers on the battlefield
Date:2/15/2013

olution to develop an antibody that could be attached to the hydrogels to cause their form to change when they encounter thrombin-activated fibrin. The resulting antibody has high affinity for the polymerized form of fibrin and low affinity for the precursor.

"We knew the molecule that we wanted and we knew the domains that were critical for recognition," Barker said. "The primary design concept was the ability to recognize an active, forming clot from the soluble, inactive precursor."

The artificial platelets have so far been tested in rats, and separately using in vitro simulated endothelial systems in the laboratory of Wilbur Lam, an assistant professor at Emory University in Atlanta. Though the work is a long way from a device that could be used on the battlefield, Barker envisions transitioning the research to a startup company that develop the technology to improve survivability for wounded soldiers.

"You could have it literally in the pocket of any soldier, who could pop it out when needed," Barker explained. "As the needle is extended, you would break the package of freeze-dried particles. The device would then be placed on the abdomen, where the particles would be injected into the bloodstream. They would circulate inactive until they encountered the initiation of clotting."

Once the bleeding was stopped, cytokines and anti-inflammatory compounds within the "designer" clot could help determine the phenotype that should be adopted by healing cells and regulate their behavior. That would set the stage for the subsequent healing process.

To help soldiers already suffering from the effects of fibrosis the contraction of scarred tissue the researchers are developing a polymer to which a natural peptide is attached. The peptide helps regulate the repair process that produces scars and could ultimately help reduce or reverse the effects of fibrosis. The technique has reversed the effects of pulmonary fibrosis in an a
'/>"/>

Contact: John Toon
jtoon@gatech.edu
404-894-6986
Georgia Institute of Technology
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. Artificial retina receives FDA approval
2. Artificial atoms allow for magnetic resonance on individual cells
3. Nanomaterials key to developing stronger artificial hearts
4. U. of Minn. researchers unveil first artificial enzyme created by evolution in a test tube
5. Cornell engineers solve a biological mystery and boost artificial intelligence
6. Scale-up of a temporary bioartificial liver support system described in BioResearch Open Access
7. New geometries: Researchers create new shapes of artificial microcompartments
8. High-speed video and artificial flowers shed light on mysteries of hummingbird-pollinated flowers
9. Researchers develop method to grow artificial tissues with embedded nanoscale sensors
10. Artificial intelligence helps detect subtle differences in mutant worms
11. UD partner in NIH research project to produce artificial salivary glands
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Artificial platelets could treat injured soldiers on the battlefield
(Date:7/9/2014)... Calif. Jason Stajich , an associate professor ... University of California, Riverside, has been awarded the 2014 ... America, a scientific society dedicated to advancing the science ... kinds including mushrooms, molds, truffles, yeasts, lichens, plant pathogens, ... and each year recognizes an outstanding early-career mycologist. Stajich ...
(Date:7/9/2014)... species, selection for traits that are attractive to the ... opportunities to mate, the tail of male peacocks being ... California, Riverside have now found that sexual selection and ... linked. Describing the life histories of more than 150 ... found that species with placentas tend to have males ...
(Date:7/9/2014)... studying critically ill children with traumatic injuries have ... are likely to develop a hospital-acquired infection. The ... and published online in June in the journal ... efforts that could lead to the clinical implementation ... prevent or reverse immune system damage following critical ...
Breaking Biology News(10 mins):UC Riverside plant pathologist receives national recognition 2Biologists link sexual selection and placenta formation 2Biologists link sexual selection and placenta formation 3Biologists link sexual selection and placenta formation 4Immune function predicts infection risk among child trauma patients 2Immune function predicts infection risk among child trauma patients 3
... tree ring-based reconstruction of an extinct polar forest,s ... impact of Lake St. Martin bolide on groundwater ... boundary; radar images of volcanic and impact deposits ... into the atmosphere; use of charred plants in ...
... -- The National Academy of Sciences (NAS) will honor ... the areas of biology, chemistry, solar physics, ecology, mathematics, ... awards and recipients for 2008 are: ARCTOWSKI MEDAL ... well as a gift of $60,000 to an institution ...
... Climate Change for the Baltic Sea Basin (BACC), the book ... and possible future climate change in the region, which extends ... mid-Europe. One of the key findings is that air temperatures ... five degrees Celsius from now to 2100. More than 80 ...
Cached Biology News:February Geology and GSA Today media highlights 2February Geology and GSA Today media highlights 3February Geology and GSA Today media highlights 4February Geology and GSA Today media highlights 5February Geology and GSA Today media highlights 6February Geology and GSA Today media highlights 7February Geology and GSA Today media highlights 8February Geology and GSA Today media highlights 9February Geology and GSA Today media highlights 10Academy honors 13 for major contributions to science 2Academy honors 13 for major contributions to science 3Academy honors 13 for major contributions to science 4Academy honors 13 for major contributions to science 5Climate change in the Baltic Sea basin -- past, present and future 2Climate change in the Baltic Sea basin -- past, present and future 3
(Date:1/15/2014)... TaiGen Biotechnology Company, Limited ("TaiGen") today announced that they ... Russian pharmaceutical company, to develop and commercialize nemonoxacin (Taigexyn ... , Turkey and other members ... antibiotic for the treatment of bacterial infections including those ...
(Date:1/14/2014)... , Jan. 14, 2014  3D Communications, a leading provider of strategic ... business, and media events in the United States ... associate Virginia Cox , JD, is returning to the firm,s ... Cox re-joins 3D after more than two years of service ...
(Date:1/14/2014)... BETHESDA, Md. , Jan. 14, 2014  Organovo ... institutes from the National Institutes of Health (NIH) to ... more effective treatments to patients on a faster timeline. ... Translational Sciences (NCATS) and the National Eye Institute (NEI) ...
(Date:1/14/2014)... 14, 2014 Global Record Systems, ... information technology solutions for patients, physicians, the biopharmaceutical ... announced today the signing of a three-year Research ... Drug Administration (FDA). This initiative is designed ...
Breaking Biology Technology:TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 2TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 3TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 4Former FDA Associate Commissioner Returns To 3D Communications 2Organovo Announces Collaboration with National Institutes of Health 2Organovo Announces Collaboration with National Institutes of Health 3Global Record Systems Announces Research Collaboration Agreement with FDA to Create a Novel “Big Data” Paradigm for Collection of Patient Safety and Outcomes Information 2
... SAN DIEGO, Feb. 3 Gen-Probe Incorporated (Nasdaq: ... has joined the Company as senior vice president, research ... expertise and leadership to our already strong senior management ... officer. "We believe Eric will play an integral ...
... Primary and Key Secondary Endpoints -- CAPACITY 1 Misses ... Submit NDA and MAA -BRISBANE, Calif., Feb. 3 ... results from the two Phase 3 CAPACITY studies evaluating ... The primary endpoint of change in percent predicted Forced ...
... is like none other. To mark the observance, African ... promote science education, achievement motivation and positive psychological development among ... ... Washington, DC (PRWEB) February 3, 2009 -- African Ancestry, Inc., ...
Cached Biology Technology:Eric Lai Joins Gen-Probe as Senior Vice President, Research and Development 2InterMune Reports Results of Two Phase 3 CAPACITY Studies of Pirfenidone in IPF 2InterMune Reports Results of Two Phase 3 CAPACITY Studies of Pirfenidone in IPF 3InterMune Reports Results of Two Phase 3 CAPACITY Studies of Pirfenidone in IPF 4InterMune Reports Results of Two Phase 3 CAPACITY Studies of Pirfenidone in IPF 5InterMune Reports Results of Two Phase 3 CAPACITY Studies of Pirfenidone in IPF 6InterMune Reports Results of Two Phase 3 CAPACITY Studies of Pirfenidone in IPF 7InterMune Reports Results of Two Phase 3 CAPACITY Studies of Pirfenidone in IPF 8InterMune Reports Results of Two Phase 3 CAPACITY Studies of Pirfenidone in IPF 9InterMune Reports Results of Two Phase 3 CAPACITY Studies of Pirfenidone in IPF 10InterMune Reports Results of Two Phase 3 CAPACITY Studies of Pirfenidone in IPF 11African Ancestry, Educators, Identity Experts Launch DNA Education Project during Historic Black History Month; 7th Graders Score High on Ultimate Self Test 2African Ancestry, Educators, Identity Experts Launch DNA Education Project during Historic Black History Month; 7th Graders Score High on Ultimate Self Test 3
...
The S. cerevisiae Hansen strains are the parental yeast strains from which the deletions were derived....
The DNA DipStick Kit is ideal for estimating nucleic acid concentrations and approximate yields. Works with ss- and ds-DNA, RNA, and oligonucleotides at concentrations as low as 0.1 ng/l....
... The NEW HandyStep electronic from BRAND ... pipetting. It is the only electronic, ... standard syringe tips, including BRAND PD-Tip ... Plus, Fisherbrand Dispenser Tips,and VWRbrand Combi-Syringes. ...
Biology Products: