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Artificial muscles that do the twist
Date:2/26/2014

team mimicked the kind of damage that happens to the heart muscle under certain disease conditions. For example, a diseased heart after a heart attack exhibits a less pronounced left ventricular twist due to local damage that extends through the heart wall.

Eventually the team hopes to develop biocompatible versions of the matrix as one of several next steps toward a new kind of implantable cardiac device, said Roche, whose co-advisors are Walsh and Wyss Institute Core Faculty member David Mooney. Mooney, Ph.D., another coauthor on the publication, is also the Robert P. Pinkas Family Professor of Bioengineering at SEAS.

"The motion of most mechanically active cardiac devices is currently tested in 2D," said Wyss Institute Founding Director Don Ingber, M.D., Ph.D. "This new breakthrough provides a much better test-bed for these types of devices and it could inspire a whole new class of cardiac therapies, such as improved ventricular assist devices that mimic natural heart motion."


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Contact: Kristen Kusek
kristen.kusek@wyss.harvard.edu
617-432-8266
Wyss Institute for Biologically Inspired Engineering at Harvard
Source:Eurekalert  

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