Navigation Links
Artificial enzyme removes natural poison
Date:8/26/2010

For the first time ever, a completely man-made chemical enzyme has been successfully used to neutralise a toxin found naturally in fruits and vegetables.

While studying for her PhD in chemistry at the University of Copenhagen Dr. Jeannette Bjerre showed how a novel so-called chemzyme was able to decompose glycoside esculin, a toxin found in horse-chestnuts.

Proof of concept for artificial enzymes

Chemzymes are designed molecules emulating the targeting and efficiency of naturally occurring enzymes and the recently graduated Dr. Bjerre is pleased about her results.

"Showing that these molecules are capable of decomposing toxins required vast amounts of work and time. But it's been worth every minute because it proves the general point that it's possible to design artificial enzymes for this class of task", explains Bjerre.

Simple molecules performing complex tasks

Most people know enzymes as an ingredient in detergents. In our bodies enzymes are in charge of decomposing everything we eat, so that our bodies can absorb the nutrients. But they also decompose ingested toxins, ensuring that our bodies survive the encounter.

In several important aspects artificial enzymes function in the same way as naturally occurring ones. But where natural enzymes are big and complex, the artificial ones have been pared down to the basics.

The flat-nosed plier of the molecular world

One consequence of this is that designing chemzymes for targeted tasks ought to be easier. With fewer parts, there's less to go wrong when changing the structure of chemzymes. And for enzymes as well as for their artificial counterparts even small changes in structure will have massive consequences for functionality.

In this, enzymes are very much like hand-tools, where scissors and flat nosed pliers, though almost identical, have very different duties.

Hardwearing replacement enzymes '/>"/>

Contact: Jes Andersen
jean@science.ku.dk
453-050-6582
University of Copenhagen
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Taking the next step toward advanced artificial limbs
2. Researchers design artificial cells that could power medical implants
3. Evolved Machines Selected as a Prime Contractor for DARPA Program to Engineer an Artificial Olfaction System
4. Scientists identify cell changes leading to impaired artificial kidney function
5. Biomedical researchers create artificial human bone marrow in a test tube
6. TECNALIA uses artificial vision to improve recycling of electronic scrap metal
7. Artificial cells, simple model for complex structure
8. Red pandas reveal an unexpected (artificial) sweet tooth
9. Development of an artificial simulator of the nervous system to do research into diseases
10. Non-wovens as scaffolds for artificial tissue
11. Progress toward artificial tissue?
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Artificial enzyme removes natural poison
(Date:12/10/2014)... Dec. 08, 2014 Research and Markets ... of the "Biometrics Market in Japan 2014-2018" ... http://photos.prnewswire.com/prnh/20130307/600769 The integration ... as rural banking and upgradation of the driver,s ... in the market. Besides the aforementioned projects, biometrics ...
(Date:12/5/2014)... -- Tute Genomics, a leader in cloud-based solutions for genome ... led by UK-based Eurovestech. Peak Ventures and a number ... "We are at a pivotal time in ... seeks new approaches for the diagnosis, treatment and prevention ... and CEO of Tute Genomics. "One of the main ...
(Date:12/3/2014)... 2014 As part of our commitment to ... pleased to announce the release of a new reader ... the workforce data that they need. The ... by existing readers. Many such devices have serious shortcomings ... technology. Older models force users to navigate numerous complicated ...
Breaking Biology News(10 mins):Biometrics Market in Japan 2014-2018: Key Vendors are DDS, Fujitsu, Hitachi and NEC 2Tute Genomics Raises $2.3 Million to Scale Up Cloud-Based Genome Analytics and Accelerate Personalized Medicine 2Tute Genomics Raises $2.3 Million to Scale Up Cloud-Based Genome Analytics and Accelerate Personalized Medicine 3Inception Technologies to Release New Biometric Reader 2
... every day, especially wine, may be associated with an ... Dutch researchers who reported the findings of their study ... on Cardiovascular Disease Epidemiology and Prevention. , The researchers ... less than one glass per day) was associated with ...
... the University of Pennsylvania School of Medicine have discovered ... replication within cells -- use proteins that act as ... structure. If microtubules are not formed properly such basic ... which may have implications in such disease processes as ...
... on Mars do not drill deep enough to find the ... surface of Mars, according to research led by UCL (University ... that life once existed on Mars, cellular life could not ... the surface of Mars than a few metres deep ?beyond ...
Cached Biology News:Light wine intake is associated with longer life expectancy in men 2Light wine intake is associated with longer life expectancy in men 3Light wine intake is associated with longer life expectancy in men 4Molecular motors and brakes work together in cells 2Dig deeper to find Martian life 2Dig deeper to find Martian life 3
(Date:12/24/2014)... 2014 PharmaBoardroom,s new report, ... and available for free download , digs deep into ... growth in the sector today. One area where ... been in developing a homegrown pharmaceutical manufacturing base, even if ... remains some way off. A cursory comparison with neighboring ...
(Date:12/24/2014)... , Dec. 23, 2014  NeuroLifeSciences announced today ... in children with attention deficit/hyperactivity disorder published in ... The paper, titled "Pilot Phase 2 ... ( Konofal et al, Drug Des Devel ... shows that mazindol might be an effective, well-tolerated, ...
(Date:12/22/2014)... , Dec. 22, 2014 /PRNewswire/ - RepliCel Life ... regenerative medicine company focused on the development of autologous ... out of the University of Calgary in conjunction with ... Carolina, which further validates the company,s ongoing clinical research ... effects of pattern baldness. The paper entitled ...
(Date:12/22/2014)... Calif. , Dec. 22, 2014  ( www.competitivehealth.com ... CoPatient, an online medical bill review and advocacy service, ... in the FREE WellCard Savings discount health services marketplace. ... bill that was more than they expected to pay. ... reduce health care costs, WellCard Savings is pleased to ...
Breaking Biology Technology:PharmaBoardroom Releases New Algeria Pharmaceuticals Report 2PharmaBoardroom Releases New Algeria Pharmaceuticals Report 3Redefining ADHD: A New Approach & A Shift of Paradigm in ADHD Therapeutics 2Redefining ADHD: A New Approach & A Shift of Paradigm in ADHD Therapeutics 3Newly Released Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness 2Newly Released Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness 3Newly Released Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness 4Newly Released Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness 5WellCard Savings Announces CoPatient Medical Bill Review Service for Members 2
... June 24 ,WuXi PharmaTech (NYSE: WX ) ... announced,that the two companies have entered into a ... which will provide world-class preclinical,contract research services in ... located in a 323,450 square-foot, purpose-built facility in,Suzhou, ...
... The Board of,Directors of Schering-Plough Corporation (NYSE: ... per common share. Payment will be made on,Aug. 26, ... business on Aug.,1, 2008. As of March 31, 2008, ... Directors today also declared a quarterly dividend of,$3.75 per ...
... Sun Pharmaceutical,Industries Ltd. (Reuters: SUN.BO, Bloomberg: SUNP IN, NSE: ... Levitt, Chairman of the Board,of Directors of Taro Pharmaceutical ... Levitt,s letter of June 19, 2008 to Taro,s,shareholders, his ... the Initiating,Motion filed by Taro in the Tel-Aviv District ...
Cached Biology Technology:Covance and WuXi PharmaTech to Form a Joint Venture to Provide World-Class Preclinical Services in China 2Covance and WuXi PharmaTech to Form a Joint Venture to Provide World-Class Preclinical Services in China 3Covance and WuXi PharmaTech to Form a Joint Venture to Provide World-Class Preclinical Services in China 4Sun Pharmaceutical Sends Second Letter to Taro Pharmaceutical Regarding Taro's Irish Subsidiary 2Sun Pharmaceutical Sends Second Letter to Taro Pharmaceutical Regarding Taro's Irish Subsidiary 3Sun Pharmaceutical Sends Second Letter to Taro Pharmaceutical Regarding Taro's Irish Subsidiary 4Sun Pharmaceutical Sends Second Letter to Taro Pharmaceutical Regarding Taro's Irish Subsidiary 5Sun Pharmaceutical Sends Second Letter to Taro Pharmaceutical Regarding Taro's Irish Subsidiary 6Sun Pharmaceutical Sends Second Letter to Taro Pharmaceutical Regarding Taro's Irish Subsidiary 7
... Reagent B - Permeabilisation medium LEUCOPERM ... suspension with Reagent A and then permeabilising ... gives antibodies access to intracellular structures and ... cells intact. Specific formulations reduce background staining ...
...
Collected from calves that are 10 days old or less. Sterile, cell culture tested, US Origin...
Dako Target Retrieval Solution, Citrate pH 6 (x 10) For more information, please visit Dako' web-site. EU regulatory status: CE US regulatory status: IVD...
Biology Products: