Navigation Links
Artificial cells, simple model for complex structure
Date:2/14/2009

A simple, chemical materials model may lead to a better understanding of the structure and organization of the cell according to a Penn State researcher.

"Cells are interesting because they show organization even at the level of the cytoplasm, and while it is thought to be important for cell functions, it is not always clear how this organization is achieved," said Christine Keating, associate professor of chemistry. "We are taking a materials chemistry approach in developing simple experimental models for cytoplasm organization," she told attendees at the 2009 Annual Meeting of the American Association for the Advancement of Science.

Cytoplasm is the material that fills the cell and is crowded with very large molecules. It surrounds the organelles -- tiny organs like mitochondria and the nucleus. Unlike organelles, the cytoplasm is a fundamental feature of all cells. Many important biochemical processes take place here, and so cytoplasm is interesting as a major player in cell function.

Creating a cell with organelles would be a monumental task, but creating one that exhibits molecular crowding and heterogeneity -- unevenness of composition -- is possible using large polymeric molecules and a lipid membrane.

Keating uses lipids to create vesicles, tiny cell-sized bubbles of lipid membrane in an aqueous solution of two large polymers. In one case she used poly(ethyleneglycol) (PEG) -- a common polymer -- and dextran -- a polymerized sugar to create the cell.

"Neither of these compounds is important in a cell, but they illustrate the possibility of partitioning large molecules within a cell without internal membranes," said Keating. Cytoplasm is usually filled with macromolecules of proteins, nucleic acids and carbohydrates.

A mixture of a small amount of PEG, a small amount of dextran, water and dried lipid allowed the lipid to rehydrate and form the vesicles. The PEG and dextran filled the vesicles to the same concentratio
'/>"/>

Contact: A'ndrea Elyse Messer
aem1@psu.edu
814-865-9481
Penn State
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Yale scientists create artificial cells that boost the immune response to cancer
2. M2SYS Introduces Revolutionary Biometric Artificial Intelligence Technology to Significantly Reduce Fingerprint Software False Reject Rates
3. Undergrad has sweet success with invention of artificial Golgi
4. Artificial Gravity receives 2008 Life Science Book Award
5. Complex ocean behavior studied with artificial upwelling
6. Taking the next step toward advanced artificial limbs
7. Researchers design artificial cells that could power medical implants
8. Evolved Machines Selected as a Prime Contractor for DARPA Program to Engineer an Artificial Olfaction System
9. Scientists identify cell changes leading to impaired artificial kidney function
10. Biomedical researchers create artificial human bone marrow in a test tube
11. TECNALIA uses artificial vision to improve recycling of electronic scrap metal
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Artificial cells, simple model for complex structure
(Date:9/30/2014)... HEIGHTS, Ill. (September 30, 2014) People who suffer ... can do to control their asthma besides properly taking ... a new article in the Annals of Allergy, ... American College of Allergy, Asthma and Immunology (ACAAI), asthma ... examining their lifestyle. The woman described in the Annals ...
(Date:9/29/2014)... Clostridium ramosum , coupled with a high-fat diet, may ... week in mBio , the online open-access journal of ... from the German Institute of Human Nutrition Potsdam-Rehbruecke in Nuthetal ... ramosum gained weight when fed a high-fat diet. Mice ... obese even when consuming a high-fat diet, and mice that ...
(Date:9/29/2014)... WASHINGTON, DC September 29, 2014 -- Plants ... ,commensal, bacteria help the pants extract nutrients and ... preventing pathogens from contaminating fruits and vegetables. Now, ... commensal bacteria inside of seeds; thus ensuring that ... researchers, from the University of Notre Dame, presented ...
Breaking Biology News(10 mins):Asthma symptoms kicking up? Check your exposure to air pollution 2Gut bacteria promote obesity in mice 2Plants prepackage beneficial microbes in their seeds 2
... possibility that life exists beyond Earth. The quest for ... "following the water" turns out to be too general ... possess liquid water is growing faster than can be ... teams, Arizona State University researchers intend to boost extraterrestrial ...
... evolutionary biologists are still debating this question, a ... PLoS ONE, supports the view that the ... thousands of years before the French Revolution, Marx, ... power struggle and their origin had dramatic implications ...
... A UC Riverside-led team of biomedical scientists has found that ... acne and skin infections, can be used to treat ... mental impairment and the most common cause of autism. ... approval of a new clinical trial in Toronto, Canada, that ...
Cached Biology News:NASA picks ASU research team to guide study of search for life 2NASA picks ASU research team to guide study of search for life 3Egalitarian revolution in the Pleistocene? 2Egalitarian revolution in the Pleistocene? 3Egalitarian revolution in the Pleistocene? 4UCR researchers propose minocycline as a promising drug for patients with Fragile X syndrome 2UCR researchers propose minocycline as a promising drug for patients with Fragile X syndrome 3
(Date:10/1/2014)... , Oct. 1, 2014  Discovery Laboratories, ... has been awarded a Phase II Small Business ... $3.0 million from the National Institute of Allergy ... of Health (NIH) to support the development of ... a medical countermeasure to mitigate acute and chronic/late-phase ...
(Date:10/1/2014)... Switzerland (PRWEB) October 01, 2014 ... the quality of the final product. However, while ... regulated, regulatory frameworks such as Good Manufacturing Practices ... the responsibility of the manufacturer to interpret these ... consistent weighing performance quality. METTLER TOLEDO experts have ...
(Date:10/1/2014)... Pfanstiehl has announced the launch of ... the USA under ICH ... for playing a key role in protein glycosylation.  ... that media supplementation with mannose can improve overall ... to Dr. Christopher Wilcox , VP, Business ...
(Date:10/1/2014)... (PRWEB) September 30, 2014 The participants ... designs, but to spending their own time adjusting, tweaking ... their complex designs were ready for judging. , “I ... design firm thought leader. “The entries showed a ... the physical characteristics of the print medium and the ...
Breaking Biology Technology:Discovery Labs Receives SBIR Grant Valued up to $3.0 Million to Support Development of Aerosolized KL4 Surfactant to Address Radiation-Induced Lung Injury 2Discovery Labs Receives SBIR Grant Valued up to $3.0 Million to Support Development of Aerosolized KL4 Surfactant to Address Radiation-Induced Lung Injury 3Comply with Weighing-Related Regulations in Pharma Manufacturing 2Pfanstiehl Launches cGMP-produced Mannose for Cell Culture Media Optimization & Glycoprotein Biosynthesis 2Array Architects Challenges Staff to Create with 3D Printer 2
... Dec. 30, 2010 Renowned biotech specialist, venture ... predictions for biotech. He sees a dynamic industry writing ... that: favors risk mitigated companies rather than earlier stage ... emerging biotech markets, particularly in Brazil, Chile, China, India, ...
... and pilot whales that are known to have anti-fouling ... are using nanotechnology to create synthetic, chemical-free, anti-bacterial surfaces. ... as S. aureus and E. coli ... devices, lenses and even ship hulls. Conventional methods for ...
... STATION, Dec. 23, 2010 An international team of ... announced a breakthrough that gives a new spin to ... The team has developed an electrically controllable device whose ... the culmination of a 20-year scientific quest involving many ...
Cached Biology Technology:Biotech Guru G. Steven Burrill Offers his Predictions on What Lies Ahead for the Biotech Industry in 2011 2Biotech Guru G. Steven Burrill Offers his Predictions on What Lies Ahead for the Biotech Industry in 2011 3Biotech Guru G. Steven Burrill Offers his Predictions on What Lies Ahead for the Biotech Industry in 2011 4Singapore consortium learns from nature to produce new chemical-free, anti-bacteria plastic 'skins' 2Singapore consortium learns from nature to produce new chemical-free, anti-bacteria plastic 'skins' 3Texas A&M professor helps develop first high-temp spin-field-effect transistor 2Texas A&M professor helps develop first high-temp spin-field-effect transistor 3
... Mini-Sub cell GT cell and PowerPac basic power ... of nucleic acids in agarose gels. The Mini-Sub ... with cables and electrodes, a 7 x 7 ... casting gates, and two 1.5 mm fixed-height combs ...
... 96 and PowerPac basic power supply are used ... in agarose gels. This Model 96 cell includes ... UV-transparent gel tray with fluorescent ruler, and a ... and 220-240 V, provides output of 10-300 V, ...
... basic power supply are used for submerged horizontal ... This Model 192 cell includes a buffer tank, ... with fluorescent ruler, and a gel caster. The ... provides output of 10-300 V, 4-400 mA, and ...
... The Sequi-Gen GT and PowerPac 3000 system, ... using a 38 x 30 cm vertical slab ... GT electrophoresis cell, which is capable of separating ... an integral plate chamber (IPC) assembly (IPC and ...
Biology Products: