Navigation Links
Arsenic and old toenails
Date:2/22/2009

Scientists from Leicester and Nottingham have devised a method for identifying levels of exposure to environmental arsenic by testing toenail clippings.

Arsenic occurs naturally in the environment and people can be exposed to it in several ways, for example through contaminated water, food, dust or soil. The risk of exposure is greater in certain areas of the UK where the natural geology and historic mining activities have led to widespread contamination of the environment with arsenic. Long term exposure to arsenic is associated with increases in lung, liver, bladder and kidney cancers and skin growths.

Previous studies using hair have suggested high levels of arsenic in the bodies of King George III and Napoleon Bonaparte. Now doctoral research at the British Geological Survey by Mark Button of the University of Leicester has used toenail clippings to find fresh evidence of exposure to environmental arsenic within a UK population living close to a former arsenic mine. The research, published online ahead of print in the Journal of Environmental Monitoring, was carried out with Dr Gawen Jenkin, Department of Geology, University of Leicester; Dr Chris Harrington, School of Science and Technology at Nottingham Trent University and Dr Michael Watts of the British Geological Survey. The research was funded by the British Geological Survey.

Mark Button said "We initially identified high levels of arsenic in earthworms living in contaminated soils surrounding the former mine. That got us thinking about potential exposure in people living close to the site."

The researchers collected toenails and washed and acid digested the samples under microwave irradiation. They then analysed the samples using inductively coupled plasma mass spectrometry.

Mark Button added: "This preliminary research indicates that people living close to a former arsenic mine have elevated levels of arsenic in their toenails. However, the potential health risks in this case, if any, are not yet clear and no arsenic related health issues have been reported. A large-scale and more detailed biomonitoring study is required to confirm these initial results."

Dr Jenkin, lecturer in Applied Geology at the University of Leicester said: "This is the first time that the chemical form of the arsenic in the toenails has been measured that can tell us something about how it got in there and possible risk factors.

Dr Jenkin added: "There is definitely more research needed to look at - amongst other things - a larger sample of volunteers, to see if the values change with time (it is quite possible the high values recorded are a one-off for that person, or due to slow toenail growth concentrating harmless quantities of arsenic), and to look at the possible pathways by which the arsenic is ingested. Coupling our analyses with regular blood measurements would be very revealing."

However the researchers are definitely NOT requiring people to send in their toenail clippings. Neither can you assess arsenic contamination simply by looking at your toenails.

Dr Jenkin said: "Even in those people with elevated amounts it is present in tiny quantities less than 0.003% in the toenail. In people who have not been exposed at all it is less than 0.00003%. If a nail looks different from normal that is usually due to physical damage (you stubbed your toe or dropped something on it) or a minor fungal infection that can be easily cleared up by a visit to the doctor."


'/>"/>

Contact: Dr. Gawen Jenkin
grtj1@leicester.ac.uk
44-116-252-3934
University of Leicester
Source:Eurekalert

Related biology news :

1. Folic acid lowers blood arsenic levels, according to Mailman School of Public Health study
2. Folic acid lowers blood arsenic levels in Bangladesh
3. Dartmouth researchers show effects of low dose arsenic on development
4. MIT: Prenatal arsenic exposure detected in newborns
5. Arsenic contamination lacks one-size-fits-all remedy
6. Dartmouth researchers alarmed by levels of mercury and arsenic in Chinese freshwater ecosystem
7. Arsenic and new rice
8. Living sensor can warn of arsenic pollution
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/6/2017)... , Jan. 5, 2017  Delta ID Inc., a ... scanning technology for automotive at CES® 2017. Delta ID ... ) to demonstrate the use of iris scanning as ... authenticate the driver in a car, and as a ... driving experience. Delta ID and Gentex will ...
(Date:1/4/2017)...  CES 2017 – Valencell , the leading ... the launch of two new versions of its ... sensor modules that incorporate the best of Valencell,s ... The two new designs include Benchmark BE2.0, a ... Benchmark BW2.0, a 2-LED version of its original ...
(Date:12/22/2016)... Calif. , Dec. 20, 2016  As part of ... 23andMe, the leading personal genetics company, recently released its latest ... . The book focuses on the topics of inheritance ... Generation Science Standards (NGSS) taught in elementary school classrooms in ... in a series by illustrator Ariana Killoran , whose ...
Breaking Biology News(10 mins):
(Date:1/18/2017)... OF PRUSSIA, PA (PRWEB) , ... January 18, ... ... disrupt clinical operations again at the CHI SCOPE Summit for Clinical Ops Executives ... AstraZeneca in engaging panel discussions to examine vital clinical research issues such as ...
(Date:1/18/2017)... Shareholder rights law firm Johnson & Weaver, ... members of CoLucid Pharmaceuticals, Inc. (NASDAQ: CLCD ... proposed sale of the Company to Eli Lilly and ... molecules for the acute treatment of migraines. ... a definitive merger agreement with Eli Lilly. Under the ...
(Date:1/18/2017)... Research Future published a half-cooked research report on Global Cancer Diagnostics ... CAGR of 12% during the period 2016 to 2022. ... ... without any control. These abnormal cells have the ability to invade ... spread to other parts of the body through the blood and ...
(Date:1/17/2017)... 2017  An international team of researchers from ... Boniface Hospital Albrechtsen Research Centre/University of Manitoba have ... health need affecting nearly one in 15 Americans. ... their results identify small molecule drugs with neuroprotective ... injury in animal models of metabolic, chemical and ...
Breaking Biology Technology: