Navigation Links
Aria Diagnostics announces publication of first peer-reviewed data for new noninvasive prenatal test
Date:1/9/2012

San Jose, Calif., Jan. 9, 2012 Aria Diagnostics (formerly Tandem Diagnostics), a molecular diagnostics company, today announced publication of data supporting a directed, non-invasive approach to cell-free DNA (cfDNA) analysis in maternal blood for evaluation of two common fetal trisomies linked to genetic disorders. The results, assessing the detection of Trisomy 21 (associated with Down syndrome) and Trisomy 18 (associated with Edwards syndrome), were published online at http://onlinelibrary.wiley.com/doi/10.1002/pd.2922/full.

"Our ability to identify pregnancies at high risk for chromosomal abnormalities has significantly improved over the last decade, but still has limitations in precision and cost," said Dr. Ronald Wapner, director of reproductive genetics at Columbia University Medical Center. "The data shows significant improvement over presently available approaches to prenatal evaluation and will offer our patients important information about their pregnancy without the inherent risks of invasive testing."

In the study, cfDNA was analyzed from the blood samples of 298 pregnant women in the US using Aria Diagnostics' highly multiplexed assay, known as Digital Analysis of Selected Regions (DANSR), for loci on chromosomes 21 and 18. The technology was able to correctly distinguish all cases with confirmed fetal abnormalities. In contrast to other cfDNA approaches, Aria's method is more efficient and selective in analyzing genetic material, which leads to a greater than ten-fold improvement on the sequencing throughput.

"These findings demonstrate that our technology can deliver on the promise of making molecular diagnostics more affordable and accessible to a broad population," explained Ken Song, chief executive officer of Aria Diagnostics and co-author of the study. "We are very excited about this first publication that demonstrates the potential for a
'/>"/>

Contact: Traci Tournoux
ttournoux@healthstarpr.com
646-722-8830
HealthStar PR
Source:Eurekalert  

0

GOOD

Page: 1 2

Related biology news :

1. ASU and Chinas Sun Yat-Sen University to develop early diagnostics against colorectal cancer
2. Hawaii, Arkansas and Oklahoma Lead the Nation for Methamphetamine Use in the Workforce, Reveals Quest Diagnostics Drug Testing Index™
3. Faster diagnostics through cheap, ultra-portable blood testing
4. UBC megapixel DNA replication technology promises faster, more precise diagnostics
5. Gerry A. Higgins, Ph.D. Joins GenomeQuest to Foster Development of Whole Genome Diagnostics
6. Research into synthetic antibodies offers hope for new diagnostics
7. Faster CARS, less damage: NIST chemical microscopy shows potential for cell diagnostics
8. The AACR to host molecular diagnostics conference
9. AACR hosts molecular diagnostics conference in Denver, Colo.
10. AMP presents at FDA meeting on regulating diagnostics
11. Lengthening time a drug remains bound to a target may lead to improving diagnostics, therapy
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Aria Diagnostics announces publication of first peer-reviewed data for new noninvasive prenatal test
(Date:5/22/2013)... wild plants have slowed in recent years, according to ... of Leeds and the Naturalis Biodiversity Centre in the ... diversity of species in Britain, Belgium and the Netherlands ... brightened markedly after 1990, with a slowdown in local ... plants. , Professor Bill Kunin, Professor of ...
(Date:5/21/2013)... considered in the management of natural resources, and ... help them recognize and respond to the relationships ... , Place-Based Conservation: Perspectives from the Social ... Northwest Research Station,s Linda Kruger, can help managers ... is published by Springer Verlag and is available ...
(Date:5/21/2013)... researchers have developed a new method for delivering ... in the cell surface. The technique could find ... biological fields. , Bulk electroporation a technique ... nanopores in the cell membrane that are caused ... an increasingly popular method of cell transfection. (Cell ...
Breaking Biology News(10 mins):Encouraging signs for bee biodiversity 2Encouraging signs for bee biodiversity 3Single-cell transfection tool enables added control for biological studies 2
... Ariz. April 15, 2010 Fido,s wet licks might ... to findings new treatments for rare cancers and other diseases ... Research Institute (TGen) and the Van Andel Research Institute (VARI) ... to study naturally occurring cancers in dogs to better understand ...
... in both coconut oil and human breast milk lauric ... to a bioengineering graduate student from the UC San Diego ... system" published in the journal ACS Nano ... to skin-dwelling bacteria ( Propionibacterium acnes ) that cause common ...
... have developed a new way to identify the hidden ... believe ultimately could lead to a deeper understanding of ... eyes to blood pressure problems. Writing in the ... by Leonid Kruglyak, a professor in Princeton,s Department of ...
Cached Biology News:Slobbery kisses from 'man's best friend' aid cancer research 2Slobbery kisses from 'man's best friend' aid cancer research 3Slobbery kisses from 'man's best friend' aid cancer research 4Slobbery kisses from 'man's best friend' aid cancer research 5Treat acne with coconut oil and nano-bombs 2Genetic patterns rise from huge yeast samples 2Genetic patterns rise from huge yeast samples 3Genetic patterns rise from huge yeast samples 4
(Date:5/23/2013)... HILLS, Calif. , May 23, 2013  Saddleback ... recently became the first hospital on the ... robotic technology. This new surgical option provides women with ... Marc Winter , M.D., ... gynecologist and surgeon and medical director of minimally invasive ...
(Date:5/23/2013)... 2013 Northwest Biotherapeutics (NASDAQ: NWBO ... personalized immune therapies for solid tumor cancers, announced ... year,s American Society Of Clinical Oncology (ASCO) meeting in ... role in immune therapy.  (Logo: http://photos.prnewswire.com/prnh/20110329/SF73084LOGO ... the pre-eminent conference focused on clinical treatment of cancer, ...
(Date:5/23/2013)... 2013 Pusan National University Yangsan Hospital, ... and contract research company focused on research and ... today a publication reporting the induction of functional ... and immunotherapeutic vaccinia JX-594 (pexastimogene devacirepvec; Jennerex Inc.). ... the May 15 th , 2013 issue of ...
(Date:5/23/2013)... May 23, 2013 Watlow®, an ... complete thermal systems, recently introduced its new catalog, ... of experience in designing and manufacturing industrial heaters, ... products to serve diverse customer needs. , A ... at the beginning of the book. These options ...
Breaking Biology Technology:Saddleback Memorial Surgeon First on the West Coast to Perform Single-Site Robotic Hysterectomy 2Saddleback Memorial Surgeon First on the West Coast to Perform Single-Site Robotic Hysterectomy 3NW Bio Exhibit at the Upcoming ASCO Meeting to Highlight its Leadership Role in Immune Therapy for Cancer 2NW Bio Exhibit at the Upcoming ASCO Meeting to Highlight its Leadership Role in Immune Therapy for Cancer 3Pusan National University Announces Science Translational Medicine Publication Highlighting Landmark Demonstration of Functional Anti-Cancer Antibody Induction in Patients Following JX-594 Treatment 2Pusan National University Announces Science Translational Medicine Publication Highlighting Landmark Demonstration of Functional Anti-Cancer Antibody Induction in Patients Following JX-594 Treatment 3Watlow Introduces Its New Industrial Heater Catalog 2
... executives, CRN says , CRN magazine ranked Laurie ... of the top 25 executives in 2004. The magazine looked ... business. Benson ranked among executives from IBM, Cisco, Intel, Sun ... at Infosecurity Conference , Milwaukee PKWare ...
... Foundry Inc. increased sales of its media products and ... million last year, the company said on Thursday. , ,That ... $5.4 million. Last year, operational losses were greater but the ... profit of $1.5 million. , ,Sonic Foundrys flagship product is ...
... this column, I have become aware of a lot of life ... challenge of this column has been to bring them to the ... are well known, often a number of them are flying under ... case where I have never heard of a company (particularly a ...
Cached Biology Technology:Bio-Logic Systems, another Midwest life-science firm, flies under the radar 2Bio-Logic Systems, another Midwest life-science firm, flies under the radar 3Bio-Logic Systems, another Midwest life-science firm, flies under the radar 4
... reduce the chance of error. Thats the ... using Beckman Coulters extensive experience in laboratory ... the CEQ 8000 is a fully automated ... the capillary array with a patented linear ...
... Mouse monoclonal [6331] to Salmonella typhimurium The ... Enterobacteriaceae. The genus is composed of Gram-negative bacilli ... 3 major antigens; the "H" or flagellar antigen ... antigen (part of the LPS moiety) and the ...
... H-Ala-Cys-Asp-Thr-Ala-Thr-Cys-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asn-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe-NH 2 (Disulfide ... peptide and 1 ... I-labelled peptide, please see ... ([ 1 2 ...
This free-standing laminar flow hood provides a horizontal flow of HEPA-filtered air to create a clean processing area. Air return slots along the front and side edges of the work area enhance system...
Biology Products: