Navigation Links
Aria Diagnostics announces publication of first peer-reviewed data for new noninvasive prenatal test
Date:1/9/2012

San Jose, Calif., Jan. 9, 2012 Aria Diagnostics (formerly Tandem Diagnostics), a molecular diagnostics company, today announced publication of data supporting a directed, non-invasive approach to cell-free DNA (cfDNA) analysis in maternal blood for evaluation of two common fetal trisomies linked to genetic disorders. The results, assessing the detection of Trisomy 21 (associated with Down syndrome) and Trisomy 18 (associated with Edwards syndrome), were published online at http://onlinelibrary.wiley.com/doi/10.1002/pd.2922/full.

"Our ability to identify pregnancies at high risk for chromosomal abnormalities has significantly improved over the last decade, but still has limitations in precision and cost," said Dr. Ronald Wapner, director of reproductive genetics at Columbia University Medical Center. "The data shows significant improvement over presently available approaches to prenatal evaluation and will offer our patients important information about their pregnancy without the inherent risks of invasive testing."

In the study, cfDNA was analyzed from the blood samples of 298 pregnant women in the US using Aria Diagnostics' highly multiplexed assay, known as Digital Analysis of Selected Regions (DANSR), for loci on chromosomes 21 and 18. The technology was able to correctly distinguish all cases with confirmed fetal abnormalities. In contrast to other cfDNA approaches, Aria's method is more efficient and selective in analyzing genetic material, which leads to a greater than ten-fold improvement on the sequencing throughput.

"These findings demonstrate that our technology can deliver on the promise of making molecular diagnostics more affordable and accessible to a broad population," explained Ken Song, chief executive officer of Aria Diagnostics and co-author of the study. "We are very excited about this first publication that demonstrates the potential for a non-invasive test that is highly accurate, cost efficient and scalable."


'/>"/>

Contact: Traci Tournoux
ttournoux@healthstarpr.com
646-722-8830
HealthStar PR
Source:Eurekalert  

Related biology news :

1. ASU and Chinas Sun Yat-Sen University to develop early diagnostics against colorectal cancer
2. Hawaii, Arkansas and Oklahoma Lead the Nation for Methamphetamine Use in the Workforce, Reveals Quest Diagnostics Drug Testing Index™
3. Faster diagnostics through cheap, ultra-portable blood testing
4. UBC megapixel DNA replication technology promises faster, more precise diagnostics
5. Gerry A. Higgins, Ph.D. Joins GenomeQuest to Foster Development of Whole Genome Diagnostics
6. Research into synthetic antibodies offers hope for new diagnostics
7. Faster CARS, less damage: NIST chemical microscopy shows potential for cell diagnostics
8. The AACR to host molecular diagnostics conference
9. AACR hosts molecular diagnostics conference in Denver, Colo.
10. AMP presents at FDA meeting on regulating diagnostics
11. Lengthening time a drug remains bound to a target may lead to improving diagnostics, therapy
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Aria Diagnostics announces publication of first peer-reviewed data for new noninvasive prenatal test
(Date:3/15/2016)... New York , March 15, 2016 ... new market report published by Transparency Market Research "Digital Door ... Trends and Forecast 2015 - 2023," the global digital door ... US$ 731.9 Mn in 2014 and is forecast to grow ... 2023. Growth of micro, small and medium enterprises (MSMEs) across ...
(Date:3/11/2016)... 11, 2016 http://www.apimages.com ) - --> ... is available at AP Images ( http://www.apimages.com ) - ... used to produce the new refugee identity cards. DERMALOG will be ... CeBIT in Hanover next week.   --> ... be used to produce the new refugee identity cards. DERMALOG will ...
(Date:3/9/2016)... YORK , March 9, 2016 This ... and future states of the RNA Sequencing (RNA Seq) ... segments such as instruments, tools and reagents, data analysis, ... Analyze various segments of the RNA-Sequencing market such as ... services Identify the main factors affecting each segment and ...
Breaking Biology News(10 mins):
(Date:5/23/2016)... ... , ... The need for blood donations in South Texas and across the nation is growing. ... Tissue Center, blood donations are on the decline. In fact, donations across the country are ... in South Texas in the last four years alone. , There is no substitute for ...
(Date:5/23/2016)... LONDON , May 23, 2016 ... Boost Efficiency by 40% - Frontage Implement a Single ... Enforce Quality, Compliance and Traceability Within the Bioanalytical lab ... the United States and China ... deployed across its laboratory facilities. In addition to serving as the ...
(Date:5/20/2016)... ... 2016 , ... The leading Regenerative Veterinary Medicine Company, VetStem Biopharma ., ... over 100 of their own patients with the VetStem Cell Therapy. Each of these ... for their patients. , The veterinarians are Dr Ross Rich former owner of ...
(Date:5/19/2016)... ... ... Anton Paar USA, located in Ashland, Virginia is pleased to announce that ... adds a third office building to the current facilities. , Growth is nothing ... along with office space adjacent to the previous main building. Through remodels and new ...
Breaking Biology Technology: