Navigation Links
Aria Diagnostics announces publication of first peer-reviewed data for new noninvasive prenatal test
Date:1/9/2012

San Jose, Calif., Jan. 9, 2012 Aria Diagnostics (formerly Tandem Diagnostics), a molecular diagnostics company, today announced publication of data supporting a directed, non-invasive approach to cell-free DNA (cfDNA) analysis in maternal blood for evaluation of two common fetal trisomies linked to genetic disorders. The results, assessing the detection of Trisomy 21 (associated with Down syndrome) and Trisomy 18 (associated with Edwards syndrome), were published online at http://onlinelibrary.wiley.com/doi/10.1002/pd.2922/full.

"Our ability to identify pregnancies at high risk for chromosomal abnormalities has significantly improved over the last decade, but still has limitations in precision and cost," said Dr. Ronald Wapner, director of reproductive genetics at Columbia University Medical Center. "The data shows significant improvement over presently available approaches to prenatal evaluation and will offer our patients important information about their pregnancy without the inherent risks of invasive testing."

In the study, cfDNA was analyzed from the blood samples of 298 pregnant women in the US using Aria Diagnostics' highly multiplexed assay, known as Digital Analysis of Selected Regions (DANSR), for loci on chromosomes 21 and 18. The technology was able to correctly distinguish all cases with confirmed fetal abnormalities. In contrast to other cfDNA approaches, Aria's method is more efficient and selective in analyzing genetic material, which leads to a greater than ten-fold improvement on the sequencing throughput.

"These findings demonstrate that our technology can deliver on the promise of making molecular diagnostics more affordable and accessible to a broad population," explained Ken Song, chief executive officer of Aria Diagnostics and co-author of the study. "We are very excited about this first publication that demonstrates the potential for a non-invasive test that is highly accurate, cost efficient and scalable."


'/>"/>

Contact: Traci Tournoux
ttournoux@healthstarpr.com
646-722-8830
HealthStar PR
Source:Eurekalert  

Related biology news :

1. ASU and Chinas Sun Yat-Sen University to develop early diagnostics against colorectal cancer
2. Hawaii, Arkansas and Oklahoma Lead the Nation for Methamphetamine Use in the Workforce, Reveals Quest Diagnostics Drug Testing Index™
3. Faster diagnostics through cheap, ultra-portable blood testing
4. UBC megapixel DNA replication technology promises faster, more precise diagnostics
5. Gerry A. Higgins, Ph.D. Joins GenomeQuest to Foster Development of Whole Genome Diagnostics
6. Research into synthetic antibodies offers hope for new diagnostics
7. Faster CARS, less damage: NIST chemical microscopy shows potential for cell diagnostics
8. The AACR to host molecular diagnostics conference
9. AACR hosts molecular diagnostics conference in Denver, Colo.
10. AMP presents at FDA meeting on regulating diagnostics
11. Lengthening time a drug remains bound to a target may lead to improving diagnostics, therapy
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Aria Diagnostics announces publication of first peer-reviewed data for new noninvasive prenatal test
(Date:3/28/2017)... PUNE, India , March 28, 2017 ... (Analog, IP, Biometrics), Hardware (Camera, Monitors, Servers, Storage Devices), ... Maintenance), Vertical, and Region - Global Forecast to 2022", ... 30.37 Billion in 2016 and is projected to reach ... 15.4% between 2017 and 2022. The base year considered ...
(Date:3/24/2017)... March 24, 2017 The Controller General of Immigration ... Abdulla Algeen have received the prestigious international IAIR Award for ... Continue Reading ... ... Deputy Controller Abdulla Algeen (small picture on the right) have received the ...
(Date:3/23/2017)... 23, 2017 The report "Gesture Recognition and Touchless Sensing ... Geography - Global Forecast to 2022", published by MarketsandMarkets, the market is expected ... 29.63% between 2017 and 2022. Continue Reading ... ... ...
Breaking Biology News(10 mins):
(Date:4/20/2017)... April 20, 2017 For today, Stock-Callers.com ... novel drug development and clinical research aimed at treating diseases ... (NASDAQ: BSTG), Keryx Biopharmaceuticals Inc. (NASDAQ: KERX), Kite Pharma Inc. ... ). You can access our complimentary research reports on these ... ...
(Date:4/19/2017)... ... , ... Alisa Wright, founder and CEO of Singota Solutions , has ... in Lafayette, Indiana. , The Distinguished Alumni Award was established in 1984 to ... scientific endeavors. , Wright began her career in the pharmaceutical industry with firms ...
(Date:4/19/2017)... ... April 19, 2017 , ... ThermaGenix, the PCR ... event adds to several other early achievements at ThermaGenix, including the business formation ... , ThermaGenix will use proceeds from the Series A-1 round to:, ...
(Date:4/19/2017)... and PUNE, India , April 19, 2017 /PRNewswire/ ... "Membrane Microfiltration Market: Global Opportunity Analysis and Industry Forecast, 2014-2022 ," the global ... $12,858 million by 2022, registering a CAGR of 9.6% from 2016 to 2022. ... ... ...
Breaking Biology Technology: