Navigation Links
Argonne scientists develop techniques for creating molecular movies
Date:4/15/2008

ARGONNE, Ill. (April 15, 2008) They may never win an Oscar, but scientists at the U.S. Department of Energys (DOE) Argonne National Laboratory have developed techniques for creating accurate movies of biological and chemical molecules, a feat only theorized up until now.

Biological and organic molecules in solution are far more complex than the standard crystalline structures of salt or metals since they are constantly moving and changing over time. These motions have not yet been seen directly, but scientists using the high intensity x-rays at the Advanced Photon Source have measured images that are blurred by these motions and have used them to create more accurate movies of molecular motions.

Computer simulations are currently the only way to visualize molecular motions in solution, but researchers have not had a means to check the accuracy of these simulations for complex molecules. For the first time, scientists can see the movements first hand and compare them to their theoretical counterparts.

The blurring that we see in our solution x-ray patterns are remarkably sensitive to the type of the molecular motion, senior chemist David Tiede said. For the first time, we are able to test the accuracy of the simulation and change it to fit data better. Without it, we had no way of knowing how accurate the models were.

Tiede hopes an improved accuracy in molecular modeling will give insights into the structure and behavior of the molecules. Collaborators at the National Institutes of Health have used this approach to help determine structures of important biological molecules.

Tiede and his collaborators also plan to examine how a structure reacts to an outside stimulus. By using a laser to excite the atoms, he will create a movie that shows how the molecule reacts to the initial laser pulse and also how it returns to a stable condition.

We hope to establish between good and bad molecular actors in important chemical processes like photosynthesis, solar energy and catalysts, Tiede said. Once we see that, we can make these processes work better.


'/>"/>

Contact: Brock Cooper
bcooper@anl.gov
630-252-5565
DOE/Argonne National Laboratory
Source:Eurekalert

Related biology news :

1. Bioinformatics technology developed at Argonne provides new insight into microbial activities
2. Research at Argonnes Advanced Photon Source reveals structure and behavior of collagen
3. New Argonne study may shed light on protein-drug interactions
4. Argonne National Lab acquires first SiCortex SC5832
5. Argonne helps China create cleaner Beijing for 2008 Olympics
6. Scientists debate the accuracy of Al Gores documentary An Inconvenient Truth
7. Scientists compiled 20th century temperature data in Spain as evidence of climatic change
8. Atmospheric scientists gear up for collaborative airborne campaigns
9. AMNH scientists grace Science & Nature covers
10. Scientists uncover the potential to control adult stem cells
11. Scientists ask whether microscaffolding can help stem cells rebuild brain after stroke damage
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/11/2017)... April 11, 2017 No two people ... at the New York University Tandon School of ... have found that partial similarities between prints are ... in mobile phones and other electronic devices can ... The vulnerability lies in the fact that fingerprint-based ...
(Date:4/5/2017)... April 5, 2017  The Allen Institute for Cell ... Explorer: a one-of-a-kind portal and dynamic digital window into ... data, the first application of deep learning to create ... cell lines and a growing suite of powerful tools. ... these and future publicly available resources created and shared ...
(Date:4/4/2017)... April 4, 2017   EyeLock LLC , a ... the United States Patent and Trademark Office (USPTO) has ... the linking of an iris image with a face ... represents the company,s 45 th issued patent. ... very timely given the multi-modal biometric capabilities that have ...
Breaking Biology News(10 mins):
(Date:6/20/2017)... , ... June 20, 2017 , ... ... Robbie, PhD, a well-versed leader with extensive assay development and biomarker expertise, as ... Biomedical is a Boston CRO specializing in bio-analytical assay development and sample testing ...
(Date:6/19/2017)... ... 2017 , ... As Vice President, Product Services, Mr. Guinter ... support, and client process and SOP development. , Mr. Guinter brings a wealth ... for service providers and top-tier pharmaceuticals, and as an independent consultant supported a ...
(Date:6/19/2017)... Iowa (PRWEB) , ... June 19, 2017 , ... A ... interplay among its cells and tissues by delivering pollen and nectar containing nutrients necessary ... the means to stay healthy. , Many recent indicators point to a decline in ...
(Date:6/16/2017)... (PRWEB) , ... June 16, 2017 , ... CTNext ... Entrepreneur Innovation Awards (EIA), held at The LOFT at Chelsea Piers in Stamford. , ... ideas to a panel of judges for an opportunity to secure $10,000 awards to ...
Breaking Biology Technology: