Navigation Links
Argonne scientists develop techniques for creating molecular movies
Date:4/15/2008

ARGONNE, Ill. (April 15, 2008) They may never win an Oscar, but scientists at the U.S. Department of Energys (DOE) Argonne National Laboratory have developed techniques for creating accurate movies of biological and chemical molecules, a feat only theorized up until now.

Biological and organic molecules in solution are far more complex than the standard crystalline structures of salt or metals since they are constantly moving and changing over time. These motions have not yet been seen directly, but scientists using the high intensity x-rays at the Advanced Photon Source have measured images that are blurred by these motions and have used them to create more accurate movies of molecular motions.

Computer simulations are currently the only way to visualize molecular motions in solution, but researchers have not had a means to check the accuracy of these simulations for complex molecules. For the first time, scientists can see the movements first hand and compare them to their theoretical counterparts.

The blurring that we see in our solution x-ray patterns are remarkably sensitive to the type of the molecular motion, senior chemist David Tiede said. For the first time, we are able to test the accuracy of the simulation and change it to fit data better. Without it, we had no way of knowing how accurate the models were.

Tiede hopes an improved accuracy in molecular modeling will give insights into the structure and behavior of the molecules. Collaborators at the National Institutes of Health have used this approach to help determine structures of important biological molecules.

Tiede and his collaborators also plan to examine how a structure reacts to an outside stimulus. By using a laser to excite the atoms, he will create a movie that shows how the molecule reacts to the initial laser pulse and also how it returns to a stable condition.

We hope to establish between good and bad molecular actors in important chemical processes like photosynthesis, solar energy and catalysts, Tiede said. Once we see that, we can make these processes work better.


'/>"/>

Contact: Brock Cooper
bcooper@anl.gov
630-252-5565
DOE/Argonne National Laboratory
Source:Eurekalert

Related biology news :

1. Bioinformatics technology developed at Argonne provides new insight into microbial activities
2. Research at Argonnes Advanced Photon Source reveals structure and behavior of collagen
3. New Argonne study may shed light on protein-drug interactions
4. Argonne National Lab acquires first SiCortex SC5832
5. Argonne helps China create cleaner Beijing for 2008 Olympics
6. Scientists debate the accuracy of Al Gores documentary An Inconvenient Truth
7. Scientists compiled 20th century temperature data in Spain as evidence of climatic change
8. Atmospheric scientists gear up for collaborative airborne campaigns
9. AMNH scientists grace Science & Nature covers
10. Scientists uncover the potential to control adult stem cells
11. Scientists ask whether microscaffolding can help stem cells rebuild brain after stroke damage
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/23/2016)... March 23, 2016 ... Sicherheit Gesichts- und Stimmerkennung mit Passwörtern ... (NASDAQ: MESG ), ein führender Anbieter ... Unternehmen mit SpeechPro zusammenarbeitet, um erstmals dessen ... wird die Möglichkeit angeboten, im Rahmen mobiler ...
(Date:3/18/2016)... LONDON , March 18, 2016 ... Established Suppliers of Biometrics, ICT, Manned & Unmanned Vehicles, Physical ... & security companies in the border security market and ... and Europe has led ... your companies improved success. --> defence & ...
(Date:3/14/2016)... March 14, 2016 NXTD ) ("NXT-ID" ... commerce market, announces the airing of a new series of ... week of March 21 st .  The commercials will air ... popular Squawk on the Street show. --> NXTD ... growing mobile commerce market, announces the airing of a new ...
Breaking Biology News(10 mins):
(Date:5/26/2016)... ... May 26, 2016 , ... Kinder Scientific (KinderScientific.com), a leading ... position the Company for the future. Kinder Scientific announces restructured ownership and ... been appointed Chairman of the Board, Curtis D. Kinghorn has been appointed CEO/President ...
(Date:5/25/2016)... , ... May 25, 2016 , ... ... Fitzmaurice recently became double board-certified in surgery and surgery of the hand by ... Fitzmaurice is no stranger to going above and beyond in his pursuit of ...
(Date:5/25/2016)... Haven, Connecticut (PRWEB) , ... May 25, 2016 ... ... that the U.S. Food and Drug Administration (FDA) has granted the company’s orphan ... is the company’s second orphan drug designation granted by the FDA. , ...
(Date:5/23/2016)... San Antonio, Texas (PRWEB) , ... May 23, 2016 , ... The need for blood ... infographic released this week by the South Texas Blood & Tissue Center, blood donations are ... more than 30 years, and they are down 21 percent in South Texas in the ...
Breaking Biology Technology: