Navigation Links
Argonne scientists develop techniques for creating molecular movies
Date:4/15/2008

ARGONNE, Ill. (April 15, 2008) They may never win an Oscar, but scientists at the U.S. Department of Energys (DOE) Argonne National Laboratory have developed techniques for creating accurate movies of biological and chemical molecules, a feat only theorized up until now.

Biological and organic molecules in solution are far more complex than the standard crystalline structures of salt or metals since they are constantly moving and changing over time. These motions have not yet been seen directly, but scientists using the high intensity x-rays at the Advanced Photon Source have measured images that are blurred by these motions and have used them to create more accurate movies of molecular motions.

Computer simulations are currently the only way to visualize molecular motions in solution, but researchers have not had a means to check the accuracy of these simulations for complex molecules. For the first time, scientists can see the movements first hand and compare them to their theoretical counterparts.

The blurring that we see in our solution x-ray patterns are remarkably sensitive to the type of the molecular motion, senior chemist David Tiede said. For the first time, we are able to test the accuracy of the simulation and change it to fit data better. Without it, we had no way of knowing how accurate the models were.

Tiede hopes an improved accuracy in molecular modeling will give insights into the structure and behavior of the molecules. Collaborators at the National Institutes of Health have used this approach to help determine structures of important biological molecules.

Tiede and his collaborators also plan to examine how a structure reacts to an outside stimulus. By using a laser to excite the atoms, he will create a movie that shows how the molecule reacts to the initial laser pulse and also how it returns to a stable condition.

We hope to establish between good and bad molecular actors in important chemical processes like photosynthesis, solar energy and catalysts, Tiede said. Once we see that, we can make these processes work better.


'/>"/>

Contact: Brock Cooper
bcooper@anl.gov
630-252-5565
DOE/Argonne National Laboratory
Source:Eurekalert

Related biology news :

1. Bioinformatics technology developed at Argonne provides new insight into microbial activities
2. Research at Argonnes Advanced Photon Source reveals structure and behavior of collagen
3. New Argonne study may shed light on protein-drug interactions
4. Argonne National Lab acquires first SiCortex SC5832
5. Argonne helps China create cleaner Beijing for 2008 Olympics
6. Scientists debate the accuracy of Al Gores documentary An Inconvenient Truth
7. Scientists compiled 20th century temperature data in Spain as evidence of climatic change
8. Atmospheric scientists gear up for collaborative airborne campaigns
9. AMNH scientists grace Science & Nature covers
10. Scientists uncover the potential to control adult stem cells
11. Scientists ask whether microscaffolding can help stem cells rebuild brain after stroke damage
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/22/2017)... VILNIUS, Lithuania , March 21, 2017 /PRNewswire/ ... identification and object recognition technologies, today announced the ... development kit (SDK), which provides improved facial recognition ... safety cameras on a single computer. The new ... algorithms to improve accuracy, and it utilizes a ...
(Date:3/16/2017)... March 16, 2017 CeBIT 2017 - Against identity fraud with DERMALOG ... ... Used combined in one project, multi-biometric solutions provide a crucial contribution ... Used combined in one ... ...
(Date:3/7/2017)... 2017   HireVue , the leading provider of ... the best talent, faster, today announced the additions of ... and Diana Kucer as Chief Marketing Officer ... team poised to drive continued growth in the company,s ... of record bookings in 2017. "Companies worldwide ...
Breaking Biology News(10 mins):
(Date:3/30/2017)... 2017 In today,s pre-market research, ... Intrexon Corp. (NYSE: XON), Progenics Pharmaceuticals Inc. (NASDAQ: PGNX), ... According an article on Barron,s, Credit Suisse upgraded its rating ... March 21 st , 2017. These stocks research reports can ... ...
(Date:3/29/2017)... 29, 2017  Vermillion, Inc. (NASDAQ: VRML), a ... on its results for the fourth quarter and ... "2016 marked a pivotal year for us with ... international distribution agreements, major reimbursement progress with Medicare, ... agreements. In addition we cleared our 2 nd ...
(Date:3/29/2017)... TIKVAH, Israel , March ... (NASDAQ: BCLI), a leading developer of adult ... financial results for the year ended December ... highly successful and pivotal year for Brainstorm, with a ... made on clinical, regulatory and operational fronts," said ...
(Date:3/29/2017)... ... March 29, 2017 , ... On the heels of the ... Colpitts Clinical Trial Travel has announced that it will manage travel services for its ... the first in the United States and Europe to offer travel management services specifically ...
Breaking Biology Technology: