Navigation Links
Arg-Phe-amide-related peptides influence gonadotropin-releasing hormone neurons
Date:7/17/2013

During the last decade, our understanding of this hypothalamus-pituitary-gonadal axis has quickly expanded. Two novel hypothalamic Arg-Phe-amide- related peptides, kisspeptin and gonadotropin-inhibitory hormone, may be important regulators of the reproductive axis. Kisspeptins are currently recognized as the most potent activators of the hypothalamus-pituitary-gonadal axis. Kisspeptin and its receptor, G protein-coupled receptor 54 (GPR54), are expressed on gonadotropin-releasing hormone neurons, thus regulating the reproductive axis. Kisspeptins strongly release gonadotropin- releasing hormone and luteinizing hormone, even at pre-puberty. Kisspeptin/GPR54 is important for the regulation of sexual maturation and the development of the reproductive system. Prof. Haluk Kelestimur and colleagues from Medical School, Firat University, Elazig, Turkey used the GT17 cell line-expressing gonadotropin-releasing hormone as a model and found that gonadotropin-inhibitory hormone and Arg-Phe-amide-related peptide-1 may have inhibitory effects on kisspeptin-activated gonadotropin-releasing hormone neurons without affecting [Ca2+]i. These findings which were in the Neural Regeneration Research (Vol. 8, No. 18, 2013) that Arg-Phe-amide-related-peptide-1, in addition to Arg-Phe-amide-related-peptide-3, may be involved in the modulation of the hypothalamus- pituitary-gonadal axis.


'/>"/>

Contact: Meng Zhao
eic@nrren.org
86-138-049-98773
Neural Regeneration Research
Source:Eurekalert

Page: 1

Related biology news :

1. US Peptides Discusses HGH and Growth Hormone Releasing Peptides and How They Affect Performance
2. Early life and in utero factors found to influence testicular function in adulthood
3. Researchers determine factors that influence spinach contamination pre-harvest
4. 4 genes indentified that influence levels of bad cholesterol
5. Genetic discovery found to influence obesity in people of African ancestry
6. Scientists find surprising new influence on cancer genes
7. Environment schemes for kids influence parents behavior
8. Tendency to fear is strong political influence
9. Lady beetle diet influences its effectiveness as biocontrol agent
10. International study suggests human genes influence gut microbial composition
11. Cup color influences the taste of hot chocolate
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/7/2016)... , June 7, 2016  Syngrafii Inc. ... a business relationship that includes integrating Syngrafii,s patented ... branch project. This collaboration will result in greater ... the credit union, while maintaining existing document workflow ... http://photos.prnewswire.com/prnh/20160606/375871LOGO ...
(Date:6/2/2016)... YORK , June 2, 2016   The Weather ... is announcing Watson Ads, an industry-first capability in which consumers ... by being able to ask questions via voice or text ... Marketers have long sought ... the consumer, that can be personal, relevant and valuable; and ...
(Date:5/24/2016)... patient care by providing unparalleled technology to leaders of the medical imaging industry.  As ... added to the range of products distributed by Ampronix. Photo - ... ... ... ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... N.C. (PRWEB) , ... June 27, 2016 , ... ... commercial operations for Amgen, will join the faculty of the University of ... as adjunct professor of strategy and entrepreneurship at UNC Kenan-Flagler, with a focus ...
(Date:6/24/2016)... Brooklyn, NY (PRWEB) , ... June 24, 2016 , ... ... 15mm, machines such as the Cary 5000 and the 6000i models are higher end ... height is the height of the spectrophotometer’s light beam from the bottom of the ...
(Date:6/23/2016)... 23, 2016 /PRNewswire/ - FACIT has announced the ... biotechnology company, Propellon Therapeutics Inc. ("Propellon" or ... of a portfolio of first-in-class WDR5 inhibitors for ... as WDR5 represent an exciting class of therapies, ... medicine for cancer patients. Substantial advances have been ...
(Date:6/23/2016)... , June, 23, 2016  The Biodesign Challenge (BDC), ... new ways to harness living systems and biotechnology, announced ... (MoMA) in New York City . ... participating students, showcased projects at MoMA,s Celeste Bartos Theater ... Antonelli , MoMA,s senior curator of architecture and design, ...
Breaking Biology Technology: