Apart from psychosocial influences, biological factors have a major influence on personality traits and behaviour.
The aggregation of certain risk factors in the same individual has been shown to contribute to the development of antisocial behaviour. Research findings suggest that both the molecular and the psychosocial mechanisms underlying emotional response and antisocial behaviour may differ between males and females.
Based on gene-environment interactions, the brain monoamine systems play a crucial role in shaping personality traits and conduct disorder. The MAO genes appear to be the first genes strongly linked with either antisocial behaviour or conduct disorder.
Individuals with one set of MAO gene variants seem to be virtually independent of environment for the risk of e.g. antisocial behaviour, and in this way could explain resilience towards an unfavourable environment. In contrast, those with another set of MAO gene variants are highly dependent on psychosocial environment and have considerable vulnerability for antisocial behaviour.
|Contact: Sonja Mak|
European College of Neuropsychopharmacology