Navigation Links
Are silver nanoparticles harmful?

Silver nanoparticles cause more damage to testicular cells than titanium dioxide nanoparticles, according to a recent study by the Norwegian Institute of Public Health. However, the use of both types may affect testicular cells with possible consequences for fertility.

Commonly used

Nanotechnology is increasingly used in consumer products, medicines and building products. The potential risks of using engineered nanoparticles need to be monitored so that the industry can develop products that are safe for humans and nature.

Previous research has shown that nanoparticles can cross both the blood-brain barrier and blood-testes barrier in mice and rats, and are taken up by cells. This study aimed to see if silver and titanium dioxide nanoparticles had any effect on human and mice testicular cells.

The researchers found that silver nanoparticles had a toxic effect on cells, suppressing cellular growth and multiplication and causing cell death depending on concentrations and duration of exposure. The effect was weaker for titanium dioxide nanoparticles, although both types did cause cell type-specific DNA damage, with possible implications on reproduction as well as human and environmental health.

"It seems that the type of nanoparticle, and not the size alone, may be the limiting factor" says Nana Asare, primary author of the study published in Toxicology.

Further studies using in vivo models are needed to study the impact of nanoparticles on reproductive health.

About the study

The researchers used cells from a human testicular carcinoma cell line and testicular cells from two strains of mice, one of which is genetically modified to serve as a representative model for human male reproductive toxicity. The cells were exposed to titanium dioxide nanoparticles (21nm) and two different sizes of silver nanoparticles (20 nm and 200nm) over different concentrations and time periods. Both sizes of silver nanoparticles inhibited normal cell function and caused more cell death than the titanium dioxide nanoparticles. In particular, the 200 nm silver particles caused a concentration-dependent increase in DNA damage in the human cells.


Contact: Julie Johansen
Norwegian Institute of Public Health

Related biology news :

1. Silver cycle: New evidence for natural synthesis of silver nanoparticles
2. Nanosilver: A new name -- well-known effects
3. Antibacterial silver nanoparticles are a blast
4. Ultrasensitive imaging method uses gold-silver nanocages
5. Silver nanoparticles may one day be key to devices that keep hearts beating strong and steady
6. Nanophysics: Serving up Buckyballs on a silver platter
7. Audience Selected as Silver Winner in This Years Wall Street Journal Technology Innovation Awards and Winner of the Semiconductors Category
8. Plastic nanoparticles affect behavior and fat metabolism in fish
9. Researchers warn nanoparticles in food, vitamins could harm human health
10. Carnegie Mellon researchers use NMR to determine whether gold nanoparticles exhibit handedness
11. Scientists use laser imaging to assess safety of zinc oxide nanoparticles in sunscreen
Post Your Comments:
(Date:6/30/2017)... Today, American Trucking Associations announced Seeing ... and eye tracking software, became the newest member ... "Artificial intelligence and advanced sensing algorithms ... driver,s attentiveness levels while on the road.  Drivers ... fatigue and prevent potential accidents, which could lead ...
(Date:5/16/2017)... 2017   Bridge Patient Portal , an ... MD EMR Systems , an electronic medical record ... have established a partnership to build an interface ... GE Centricity™ products, including Centricity Practice Solution (CPS), ... These new integrations will allow healthcare delivery networks ...
(Date:4/17/2017)... NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" ... its 2016 Annual Report on Form 10-K on Thursday April 13, ... ... the Investor Relations section of the Company,s website at ... . 2016 Year Highlights: ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... New York, NY (PRWEB) , ... October 12, ... ... York Academy of Sciences today announced the three Winners and six Finalists of ... Awards are given annually by the Blavatnik Family Foundation and administered by the ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... with the pharmaceutical and biotechnology industries to improve patient outcomes and quality of ... trends in analytical testing are being attributed to new regulatory requirements for all ...
(Date:10/11/2017)... ... 11, 2017 , ... Personal eye wash is a basic first aid supply for any work ... which eye do you rinse first if a dangerous substance enters both eyes? It’s one ... with its unique dual eye piece. , “Whether its dirt and debris, or an ...
(Date:10/11/2017)... the Netherlands and LAGUNA HILLS, Calif. ... The Institute of Cancer Research, London ... use MMprofiler™ with SKY92, SkylineDx,s prognostic tool to risk-stratify patients ... trial known as MUK nine . The University of ... trial, which is partly funded by Myeloma UK, and ICR ...
Breaking Biology Technology: