Navigation Links
Are silver nanoparticles harmful?
Date:3/14/2012

Silver nanoparticles cause more damage to testicular cells than titanium dioxide nanoparticles, according to a recent study by the Norwegian Institute of Public Health. However, the use of both types may affect testicular cells with possible consequences for fertility.

Commonly used

Nanotechnology is increasingly used in consumer products, medicines and building products. The potential risks of using engineered nanoparticles need to be monitored so that the industry can develop products that are safe for humans and nature.

Previous research has shown that nanoparticles can cross both the blood-brain barrier and blood-testes barrier in mice and rats, and are taken up by cells. This study aimed to see if silver and titanium dioxide nanoparticles had any effect on human and mice testicular cells.

The researchers found that silver nanoparticles had a toxic effect on cells, suppressing cellular growth and multiplication and causing cell death depending on concentrations and duration of exposure. The effect was weaker for titanium dioxide nanoparticles, although both types did cause cell type-specific DNA damage, with possible implications on reproduction as well as human and environmental health.

"It seems that the type of nanoparticle, and not the size alone, may be the limiting factor" says Nana Asare, primary author of the study published in Toxicology.

Further studies using in vivo models are needed to study the impact of nanoparticles on reproductive health.

About the study

The researchers used cells from a human testicular carcinoma cell line and testicular cells from two strains of mice, one of which is genetically modified to serve as a representative model for human male reproductive toxicity. The cells were exposed to titanium dioxide nanoparticles (21nm) and two different sizes of silver nanoparticles (20 nm and 200nm) over different concentrations and time periods. Both sizes of silver nanoparticles inhibited normal cell function and caused more cell death than the titanium dioxide nanoparticles. In particular, the 200 nm silver particles caused a concentration-dependent increase in DNA damage in the human cells.


'/>"/>

Contact: Julie Johansen
julie.johansen@fhi.no
Norwegian Institute of Public Health
Source:Eurekalert

Related biology news :

1. Silver cycle: New evidence for natural synthesis of silver nanoparticles
2. Nanosilver: A new name -- well-known effects
3. Antibacterial silver nanoparticles are a blast
4. Ultrasensitive imaging method uses gold-silver nanocages
5. Silver nanoparticles may one day be key to devices that keep hearts beating strong and steady
6. Nanophysics: Serving up Buckyballs on a silver platter
7. Audience Selected as Silver Winner in This Years Wall Street Journal Technology Innovation Awards and Winner of the Semiconductors Category
8. Plastic nanoparticles affect behavior and fat metabolism in fish
9. Researchers warn nanoparticles in food, vitamins could harm human health
10. Carnegie Mellon researchers use NMR to determine whether gold nanoparticles exhibit handedness
11. Scientists use laser imaging to assess safety of zinc oxide nanoparticles in sunscreen
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/30/2017)... LOS ANGELES , March 30, 2017  On ... Hack the Genome hackathon at ... This exciting two-day competition will focus on developing health ... experience. Hack the Genome is ... has been tremendous. The world,s largest companies in the ...
(Date:3/30/2017)... YORK , March 30, 2017 Trends, ... type (physiological and behavioral), by technology (fingerprint, AFIS, iris ... voice recognition, and others), by end use industry (government ... and immigration, financial and banking, and others), and by ... Europe , Asia Pacific , ...
(Date:3/28/2017)... The report "Video Surveillance Market ... Storage Devices), Software (Video Analytics, VMS), and Service (VSaaS, ... to 2022", published by MarketsandMarkets, the market was valued ... to reach USD 75.64 Billion by 2022, at a ... year considered for the study is 2016 and the ...
Breaking Biology News(10 mins):
(Date:5/23/2017)... ... 2017 , ... Vortex Biosciences , provider of circulating tumor cell (CTC) ... cells using Vortex microfluidic technology ” in Nature Precision Oncology on May 8th. ... Carlo and Dr. Matthew Rettig at the University of California, Los Angeles. The publication ...
(Date:5/23/2017)... ... May 23, 2017 , ... Bacterial biofilms, surface adherent communities ... cause diverse pathologies ranging from food poisoning and catheter infections to gum disease and ... the tens of billions of dollars per year, there is currently a paucity of ...
(Date:5/22/2017)... (PRWEB) , ... May 22, 2017 , ... Stratevi, a ... expanded to the East Coast. It has opened an office in downtown Boston at ... are finding it increasingly more important to generate evidence on the value they provide, ...
(Date:5/21/2017)... ... May 19, 2017 , ... Ovation Fertility scientists’ ... American Association of Bioanalysts (AAB) and the College of Reproductive Biology (CRB) today ... AAB’s commitment to excellence in clinical laboratory services and regulations. , “We ...
Breaking Biology Technology: