Navigation Links
Are bacteria making you hungry?
Date:12/19/2012

Over the last half decade, it has become increasingly clear that the normal gastrointestinal (GI) bacteria play a variety of very important roles in the biology of human and animals. Now Vic Norris of the University of Rouen, France, and coauthors propose yet another role for GI bacteria: that they exert some control over their hosts' appetites. Their review was published online ahead of print in the Journal of Bacteriology.

This hypothesis is based in large part on observations of the number of roles bacteria are already known to play in host biology, as well as their relationship to the host system. "Bacteria both recognize and synthesize neuroendocrine hormones," Norris et al. write. "This has led to the hypothesis that microbes within the gut comprise a community that forms a microbial organ interfacing with the mammalian nervous system that innervates the gastrointestinal tract." (That nervous system innervating the GI tract is called the "enteric nervous system." It contains roughly half a billion neurons, compared with 85 billion neurons in the central nervous system.)

"The gut microbiota respond both to both the nutrients consumed by their hosts and to the state of their hosts as signaled by various hormones," write Norris et al. That communication presumably goes both ways: they also generate compounds that are used for signaling within the human system, "including neurotransmitters such as GABA, amino acids such as tyrosine and tryptophanwhich can be converted into the mood-determining molecules, dopamine and serotonin"and much else, says Norris.

Furthermore, it is becoming increasingly clear that gut bacteria may play a role in diseases such as cancer, metabolic syndrome, and thyroid disease, through their influence on host signaling pathways. They may even influence mood disorders, according to recent, pioneering studies, via actions on dopamine and peptides involved in appetite. The gut bacterium, Campilobacter jejuni, has been implicated in the induction of anxiety in mice, says Norris.

But do the gut flora in fact use their abilities to influence choice of food? The investigators propose a variety of experiments that could help answer this question, including epidemiological studies, and "experiments correlating the presence of particular bacterial metabolites with images of the activity of regions of the brain associated with appetite and pleasure."


'/>"/>

Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology
Source:Eurekalert

Related biology news :

1. RIT scientists decode 3 bacterial strains common to grapevines and sugarcane
2. Achilles heel of pathogenic bacteria discovered
3. OU study suggests the bacterial ecology that lives on humans has changed in the last 100 years
4. New edition of Bacterial Genetics text available
5. Why some strains of Lyme disease bacteria are common and others are not
6. Deciphering bacterial doomsday decisions
7. New public gut bacteria study expected to reach around world
8. Engineered bacteria can make the ultimate sacrifice
9. Video-article shows how to purify magnetic bacteria
10. New type of bacterial protection found within cells
11. Desert farming forms bacterial communities that promote drought resistance
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/23/2017)... Research and Markets has announced the addition ... - Industry Forecast to 2025" report to their offering. ... The Global Vehicle ... around 8.8% over the next decade to reach approximately $14.21 billion ... estimates and forecasts for all the given segments on global as ...
(Date:3/22/2017)... 21, 2017 Optimove , provider ... retailers such as 1-800-Flowers and AdoreMe, today announced ... and Replenishment. Using Optimove,s machine learning algorithms, these ... and replenishment recommendations to their customers based not ... of customer intent drawn from a complex web ...
(Date:3/20/2017)... 2017 At this year,s CeBIT Chancellor Dr. ... DERMALOG. The Chancellor came to the DERMALOG stand together with the Japanese ... CeBIT partner country. At the largest German biometrics company the two government ... and iris recognition as well as DERMALOG´s multi-biometrics system.   ... ...
Breaking Biology News(10 mins):
(Date:5/24/2017)... ... May 24, 2017 , ... Today, the South ... Recovery’s Advanced Biological Nutrient Recovery (ABNR™) technology at its 4,000,000 gallon per day ... upgrade to sustainably meet current and future nutrient discharge regulations. The ABNR platform, ...
(Date:5/23/2017)... Canada (PRWEB) , ... May 23, 2017 , ... ... Firmex FileSend, a cloud-based file transfer solution that makes it easy for organizations ... without having to worry about cumbersome FTP software or email file size limitations. ...
(Date:5/23/2017)... BELLINGHAM, Washington, USA (PRWEB) , ... May 22, ... ... SPIE Optics and Photonics 2017 in San Diego, California, this August ... virtual reality, solar fuels, and autonomous vehicles. , SPIE Optics and Photonics, the ...
(Date:5/23/2017)... ... May 23, 2017 , ... Cambridge Semantics , the leading ... year’s Bio-IT World Conference and Expo in Boston May 23-25 with a ... The Anzo Smart Data Lake is also a finalist for the Best of ...
Breaking Biology Technology: