Navigation Links
Archive of failed joint replacements provides tips to building a better hip replacement
Date:2/7/2012

e a joint revision surgery at Hospital for Special Surgery, doctors have collected and saved the failed implants for research. At the same time, they have created a web-based system to file information on the implant, such as the manufacturer, and on the patient, such as age, weight and activity level. Doctors at HSS perform roughly 8,000 joint replacement surgeries per year and roughly 10% are revision surgeries, so this database is growing by about 800 specimens per year. Many patients who have had their joint replacement surgeries elsewhere come to Special Surgery to have revision surgery.

In the current study, HSS researchers, who did not have any ties to hip implant manufacturers, examined 46 retrieved metal-on-metal total hip replacements from 44 patients. The most common revision diagnoses were wear-related clinical concerns including osteolysis and adverse soft tissue reactions (16), loosening (11), instability (8) and infection (5). The researchers used scanning electron microscopy to determine the ways the hips were damaged, called damage modes. They found that 98 percent of the cups of the implant and 93 percent of the heads showed moderate to severe scratching. Moderate to severe pitting was found in 43 percent of the cups and 67 percent of the heads. They identified areas near the cups and heads that had completely lost their sheen.

"This study represents one of the largest collections of retrieved metal-on-metal implants," said Douglas Padgett, M.D., chief of the Adult Reconstruction and Joint Replacement Division and chief of the Hip Service at Hospital for Special Surgery. "There appears to be unique damage patterns which to date have not been identified. A follow-on analysis using high resolution laser profiling to quantify damage is in process which may yield further clues."

The patterns and similarities of the damage modes will shed light on the mechanisms behind the damage. "The goal with these hard metal-on-metal bea
'/>"/>

Contact: Phyllis Fisher
phyllis.fisher@gmail.com
212-606-1724
Hospital for Special Surgery
Source:Eurekalert

0

GOOD

Page: 1 2 3

Related biology news :

1. Why King Kong failed to impress
2. New clue to lupus: Failed autoimmune suppression mechanism
3. Environmental education has failed and must be revamped, new book argues
4. DOE Joint Genome Institute completes soybean genome
5. Exercise no danger for joints
6. Imperial College London and NTU collaborate to offer joint Ph.D. programs in engineering and science
7. Joint statement by German science organizations on green genetic engineering
8. Joint research into an enzyme that causes genetic diseases
9. Laser processes promise better artificial joints, arterial stents
10. Joint US-Norwegian study provides new insights into marine ecosystems and fisheries production
11. TNO and Seventh Wave sign letter of intent on joint preclinical pharmaceutical outsourcing services
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/18/2013)... Researchers from the United Kingdom, the Energy Department,s ... of Kentucky have recently published a paper describing ... borer Limnoria quadripunctata , commonly known as ... because they exhibit a relatively unique ability to ... microbes to break down the biomass they eat. ...
(Date:6/18/2013)... Research Council, Laboratory of Molecular Biology, has been ... Young Investigator Award. Torrent is being recognized for ... algorithm to predict antimicrobial regions in proteins. Luis ... now applying this algorithm to interrogate full genomes ... with very appealing results." , Torrent obtained ...
(Date:6/18/2013)... June 18, 2013 The herbal extract of a ... found to increase the lifespan of fruit fly populations ... Irvine researchers. , But it,s how Rhodiola ... this that grabbed the attention of study leaders Mahtab ... works in a manner completely unrelated to dietary ...
Breaking Biology News(10 mins):Novel enzyme from tiny gribble could prove a boon for biofuels research 2The American Society for Microbiology honors Marc Torrent 2Herbal extract boosts fruit fly lifespan by nearly 25 percent, UCI study finds 2
... eco-friendly fuel ethanol is usually made from grain, but the ... renewable materials that will be cost-effective alternatives, such as paper ... recently helped DOE do just that by analyzing the DNA ... structural component of plants that is also found in forestry ...
... Human embryonic stem cells (hESCs) hold great promise for ... mechanisms. Such cells can be grown in a manner ... and even without the need for immunosuppression. These were ... by an international collaboration led by Evan Y. Snyder, ...
... report citing the detrimental loss of sea ice ... many in the scientific community have been saying for years. ... Antonio's Department of Earth and Environmental Science are turning their ... warming is having similar effects in the frigid Antarctic region. ...
Cached Biology News:McBride shows DNA detective work with paper-eating bacteria that 'glide' 2McBride shows DNA detective work with paper-eating bacteria that 'glide' 3Stem cells act through multiple mechanisms to benefit mice with neurodegenerative disease 2Stem cells act through multiple mechanisms to benefit mice with neurodegenerative disease 3Stem cells act through multiple mechanisms to benefit mice with neurodegenerative disease 4Stem cells act through multiple mechanisms to benefit mice with neurodegenerative disease 5UTSA researchers examine effects of global warming on Antarctic 2
(Date:6/18/2013)... NESS ZIONA, Israel , June ... developer of complex bulk Active Pharmaceutical Ingredients (APIs), generic and ... delivery systems, announced today that the company has been granted ... Tapentadol is indicated in the US and Europe ... US Patent number 8,410,176 B2 is titled ...
(Date:6/18/2013)... This webinar will examine the history ... and review the basic FDA regulations and guiding ... these principles through real world case studies and ... on FDA regulations and guidance related to prescription ... traditional and newer forms of promotional materials for ...
(Date:6/18/2013)... 18, 2013 Research ... the addition of the "Injectable Drug ... Nanoparticles], Devices [Disposables & Reusable, Fillable & ... & Therapeutics [Diabetes & Oncology] - Global ... offering.      (Logo: http://photos.prnewswire.com/prnh/20130307/600769) , ...
(Date:6/18/2013)... As a leading provider of ... the release of their infographic - " 8 ... MeMD's goal was to leverage an information graphic ... Health 3.0 and mHealth.The infographic features a list ... and the fitness industry in unimaginable ways; turning ...
Breaking Biology Technology:Mapi Pharma Granted United States Patent for Pain Relief Medication "Tapentadol" 2Drug Advertising and Promotion Labeling: FDA Regulations, New Webinar Hosted by Xtalks 2Injectable Drug Delivery Market by Formulations, Devices & Therapeutics - Global Forecasts to 2017 2Injectable Drug Delivery Market by Formulations, Devices & Therapeutics - Global Forecasts to 2017 3MeMD, Inc Releases Infographic Featuring the Top Eight Technologies that are Revolutionizing Health and Fitness Today 2
... 5 DURECT Corporation,(Nasdaq: DRRX ) announced today ... 31, 2007. Total revenues were $6.6 million for the,three ... for the same,period in 2006. Net loss for the ... to a net loss of $9.8 million for the ...
... ST. LOUIS, Feb. 5 Monsanto Company,s ... global commercial,business, and Carl Casale, executive vice ... in separate presentations at two,conferences later this ... an update on the company,s,business performance and ...
... BEIJING and CLAREMONT, Calif., Feb. 5 /Xinhua-PRNewswire-FirstCall/ ... Board: KWBT) reports,on a meeting between Kiwa ... and Dr.,Xiao-Dong Huang from the Department of ... the possibility of collaboration in research and,development ...
Cached Biology Technology:DURECT Corporation Announces Fourth Quarter and Year End 2007 Financial Results 2DURECT Corporation Announces Fourth Quarter and Year End 2007 Financial Results 3DURECT Corporation Announces Fourth Quarter and Year End 2007 Financial Results 4DURECT Corporation Announces Fourth Quarter and Year End 2007 Financial Results 5DURECT Corporation Announces Fourth Quarter and Year End 2007 Financial Results 6DURECT Corporation Announces Fourth Quarter and Year End 2007 Financial Results 7DURECT Corporation Announces Fourth Quarter and Year End 2007 Financial Results 8DURECT Corporation Announces Fourth Quarter and Year End 2007 Financial Results 9Kiwa Bio-Tech Products Group Discusses Cooperative Research With the University of Waterloo, Canada 2Kiwa Bio-Tech Products Group Discusses Cooperative Research With the University of Waterloo, Canada 3
... contains 4 deuterium atoms at the 9, 10, ... use as an internal standard for the quantification ... is produced by the lipoxygenation of linoleic acid ... detected in atherosclerotic plaques, as an esterified component ...
5(S)-HETE-d8 is used as an internal standard for the quantification of 5(S)-HETE by stable isotope dilution mass spectrometry....
...
All-in-one mix, removes primers and dNTPs from PCR product for following direct sequencing...
Biology Products: