Navigation Links
Arbor Vita and WRAIR sign CRADA for traumatic brain injury collaboration
Date:9/8/2008

Sunnyvale, CA September 8, 2008 The U.S. Department of Applied Neurobiology at the Walter Reed Army Institute of Research (WRAIR) and Arbor Vita Corporation (AVC) have signed a Cooperative Research and Development Agreement (CRADA) for research and development of treatments for traumatic brain injury (TBI). The alliance is based on discoveries made from a collaborative effort between AVC and NoNO Inc., of Toronto, Canada, and will explore the use of the companies' NA-1 compound as a novel neuroprotective agent for severe brain injury of soldiers and civilians injured in explosions such as roadside bombs. NA-1 is an investigational compound that targets a PDZ protein and is in clinical trials for the treatment of stroke.

Arbor Vita Corporation has a novel drug development strategy targeting the PDZ family of proteins critical elements that organize and regulate many signaling pathways in cells. The disruption of PDZ interactions provides a means to control specific signaling cascades in complex diseases, including that which controls the death of neurons in the brain following a stroke. The combined research approach of WRAIR brain trauma scientists and neuroprotection experts and the neuroscience research teams of AVC and NoNO Inc. will provide a unique opportunity for conducting advanced preclinical neuroprotection research in a model of brain injury that mimics some types of battlefield injuries. The ultimate goal of the program is the advanced development of a novel therapy for the acute treatment of brain injury.

Traumatic brain injuries from bombs and other explosions are troubling consequences of modern urban and terrorist warfare for both military personnel and civilians. Every year, approximately 1,400,000 individuals in the U.S. and upwards of 2,000,000 worldwide experience traumatic brain injuries. To date, despite very encouraging preclinical results, almost all Phase II/III neuroprotection clinical trials for stroke and TBI
'/>"/>

Contact: Debra Bannister
debra.bannister@arborvita.com
530-676-8001
Arbor Vita Corporation
Source:Eurekalert

Page: 1 2

Related biology news :

1. Heavy metal link to mutations, low growth and fertility among crustaceans in Sydney Harbor tributary
2. Shipwrecks on coral reefs harbor unwanted species
3. Cold Spring Harbor Protocols highlights gene silencing, cancer cell biology methods
4. A field guide to the landscape of Cold Spring Harbor Laboratory
5. Watson-inspired innovation in research at Cold Spring Harbor Laboratory
6. Cold Spring Harbor Protocols features methods for analyzing genomes and plant cells
7. Cold Spring Harbor Protocols features classic approaches for analyzing chromosomes
8. Ugandan monkeys harbor evidence of infection with unknown poxvirus
9. Sydney harbors deadly diet for sea creatures
10. Cold Spring Harbor Laboratory scientists devise potential approach to treat spinal muscular atrophy
11. Cold Spring Harbor Protocols features methods to screen genomes and analyze evolution
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2015)... de 2015 La 10 th International Conference ... de BGI del 22 al 25 de octubre de 2015 en ... año, la conferencia celebra su décimo aniversario. Desde su inauguración ... de las reuniones anuales más influyentes del mundo en el ... dinámicas, entusiastas y mejores a nivel científico. ...
(Date:7/31/2015)... 2015 The 10 th International Conference on ... October 22-25, 2015, in Shenzhen , ... celebrating its 10 th anniversary this year. Since its inauguration ... influential annual meetings in the ,omics, fields, and is one ... ICG-10 focuses on recent breakthroughs and advances in ...
(Date:7/27/2015)... 27, 2015   Zynx Health ™, the ... improvement solutions, today announced that its ZynxCarebook ... on Android smartphones and tablets. With this expansion, ... can use ZynxCarebook to securely exchange messages and ... care transitions to other care settings, and improve ...
Breaking Biology News(10 mins):La 10th International Conference on Genomics (ICG-10) se llevará a cabo en octubre 2La 10th International Conference on Genomics (ICG-10) se llevará a cabo en octubre 3The 10th International Conference on Genomics (ICG-10) to Open in October 2Zynx Health Adds Android Device Support to ZynxCarebook Solution 2Zynx Health Adds Android Device Support to ZynxCarebook Solution 3
... New evidence reported in the August issue of Cell Stem ... on how the HIV/AIDS virus leads to learning and memory ... on the surface of the virus not only kills some ... also prevents the birth of new brain cells by crippling ...
... two proteins that bind to messenger RNA, a molecule ... into proteins, triggers the appearance of fragile X-associated tremor/ataxia ... that causes fragile X syndrome in children, said researchers ... University School of Medicine in a report that appears ...
... Aug. 15, 2007 A mysterious epidemic of thyroid ... be linked to exposure to dust shed from flame ... scientists are reporting in a study scheduled for publication ... Technology, a semi-monthly journal from the American Chemical Society, ...
Cached Biology News:HIV is a 'double hit' to the brain 2Researchers identify proteins involved in new neurodegenerative syndrome 2Study links cat disease to flame retardants in furniture and to pet food 2Study links cat disease to flame retardants in furniture and to pet food 3
(Date:7/30/2015)... globe, ISN improves the efficiency and effectiveness of contractor management systems. ISN,s online contractor ... in over 80 countries. ... ... Over 60,000 Worldwide Customers In More Than 80 Countries ... Dallas, TX , ISN has additional offices in Calgary , ...
(Date:7/30/2015)... (PRWEB) , ... July 30, 2015 , ... ... for advanced fluid applications and designed for continuous operation up to 1500 bar. ... sterilization-in-place, ensuring safety, efficiency, and preventing toxic contamination. , The Pony™ NS2006L homogenizer ...
(Date:7/29/2015)... 2015: +14% CER / 20% of sales) led the regional performance in the ... as well as solid contributions from Korea, India and ... Middle East / Africa (Q2 2015: +3% ... Turkey and the United Kingdom . ... U.S. HPV sales, on demand across all customer classes. The top seven emerging ...
(Date:7/29/2015)... Research and Markets ... the "Global Biosimilars Market, 2015 - 2025" ... Global Biosimilars Market, 2015 - 2025, report provides ... market. With the blockbuster biologics losing patent protection ... are being viewed as viable substitutes to the ...
Breaking Biology Technology:ISN Reaches Over 60,000 Worldwide Customers 2ISN Reaches Over 60,000 Worldwide Customers 3GEA Announces the Pony™ NS2006L… a Self-contained, High Pressure Lab Homogenizer for Product Development Ensuring Maximum Efficiency and Safety 2QIAGEN Reports Results for Second Quarter and First Half of 2015 2QIAGEN Reports Results for Second Quarter and First Half of 2015 3QIAGEN Reports Results for Second Quarter and First Half of 2015 4QIAGEN Reports Results for Second Quarter and First Half of 2015 5QIAGEN Reports Results for Second Quarter and First Half of 2015 6QIAGEN Reports Results for Second Quarter and First Half of 2015 7QIAGEN Reports Results for Second Quarter and First Half of 2015 8QIAGEN Reports Results for Second Quarter and First Half of 2015 9QIAGEN Reports Results for Second Quarter and First Half of 2015 10Global Biosimilars Market to 2025: Monoclonal Antibodies (mAbs), Insulin, Interferons, G-CSF/ GM-CSF, Erythropoietins and Others 2Global Biosimilars Market to 2025: Monoclonal Antibodies (mAbs), Insulin, Interferons, G-CSF/ GM-CSF, Erythropoietins and Others 3
... pure proteinTHOUSAND OAKS, Calif., Feb. 24 Bone Biologics, ... organization, Aragen Bioscience, has completed development of a recombinant ... recombinant protein. Bone Biologics has been developing the protein ... ten years of research in the lab performed by ...
... Genencor, a division of Danisco A/S, launched Accellerase(R) ... enzyme product. Genencor introduced the product at the ... in San Antonio, TX.Accellerase(R) 1500 is another significant ... made from cellulosic feedstocks, such as agricultural residues ...
... Ohio, Feb. 24 EyeScience Labs has launched ... comprehensive information and education on age-related macular degeneration (AMD) ... progressive, hereditary eye disease that is the leading cause ... the site, visitors can learn about basic eye anatomy, ...
Cached Biology Technology:Bone Biologics Announces UCB-1 (NELL-1) Bone Growth Protein Production Process With Aragen Biosciences 2Genencor Launches Accellerase(R) 1500, Next Step Toward Scale-Up of Cellulosic Ethanol 2EyeScience Launches Comprehensive Online Resource Devoted to Age-Related Macular Degeneration Education and Prevention 2
in vitro Translation, Accessory Products...
... RiboGreen RNA Quantitation Kit is one ... for the quantitation of RNA in ... 1000-fold more sensitive than absorbance measurements. ... be detected with fluorescence microplate readers ...
Donor Horse Serum US Origin...
... 53 new primer sets added in Dec ... than 3 hours , Detection from ... , Specific primers available for hundreds ... either real-time or end-point RT-PCR , ...
Biology Products: