Navigation Links
Apple or pear shape is not main culprit to heart woes -- it's liver fat
Date:12/4/2008

is the real marker. Abdominal fat probably has been cited in the past because it tends to track so closely with liver fat. But if you look at people where the two don't correspond with excess fat in the liver but not in the abdomen and vice versa the only thing that consistently predicts metabolic derangements is fat in the liver."

In a second study, Klein's team found nonalcoholic fatty liver disease was related to the release of larger amounts of fatty acids into the bloodstream that were, in turn, linked to elevated triglycerides and to insulin resistance, a key precursor to type 2 diabetes.

"Multiple organ systems become resistant to insulin in these adolescent children with fatty liver disease," he says. "The liver becomes resistant to insulin and muscle tissue does, too. This tells us fat in the liver is a marker for metabolic problems throughout the entire system."

The findings indicate that children and adults with fatty liver disease should be targeted for intensive interventions, according to Klein. Those who are obese but don't have fatty liver disease still should be encouraged to lose weight, but those with evidence of fatty liver are at particularly high risk for heart disease and diabetes. They need to be treated aggressively with therapies to help them lose weight because weight loss can make a big difference.

"Fatty liver disease is completely reversible," he says. "If you lose weight, you quickly eliminate fat in your liver. As little as two days of calorie restriction can improve the situation dramatically, and as fat in the liver is reduced, insulin sensitivity and metabolic problems improve."


'/>"/>

Contact: Jim Dryden
jdryden@wustl.edu
314-286-0110
Washington University School of Medicine
Source:Eurekalert

Page: 1 2

Related biology news :

1. Surprise in the organic orchard -- a healthier worm in the apple
2. Naturally-occurring apple compounds reduce risk of pancreatic cancer
3. Popular apple variety harbors unusual cell growth
4. Comparing apples and pears
5. Kazak apple research key to preventing blue mold
6. Carnegie Mellon developing automated systems to enable precision farming of apples, oranges
7. Facial attraction -- choice of sexual partner shaped the human face
8. Shape encoding may start in the retina
9. Grant supports study of abnormal ring-shaped chromosomes
10. Secure Services Corp. Achieves Milestone in United States Identity Protection with the Launch of the SSC SHAPE Card Management Solution
11. How cells keep in shape
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/22/2014)... French . NAIROBI (22 ... soils looming as a major threat to food security across ... the last five years, 1.7 million African farmers in 13 ... hectares and helped them double or even triple crop yields. ... in Africa (AGRA) focuses on intensive efforts initiated five years ...
(Date:8/22/2014)... in basic and clinical research and technological advances, ... complex offensive spanning multiple fronts. , Work happening ... help find new and more selective therapies for ... a specific enzyme overexpressed in certain cancersand they ... tumours. , Chemistry professor Christopher Cairo and his ...
(Date:8/22/2014)... is a multifunctional enzyme that localizes ... neuroprotective and cholesterol-synthesizing activities. DHCR24 overexpression ... amyloid β deposition. Dr. Xiuli Lu ... China constructed two recombinant adenoviruses (Ad-rSYN1-DHCR24-myc ... specifically in neuronal cells. They also ...
Breaking Biology News(10 mins):Effort to confront Africa's soil health crisis helps millions of farmers triple yields 2Effort to confront Africa's soil health crisis helps millions of farmers triple yields 3Effort to confront Africa's soil health crisis helps millions of farmers triple yields 4New enzyme targets for selective cancer therapies 2New enzyme targets for selective cancer therapies 3
... paleoclimate history by NASA,s Goddard Institute for Space Studies ... climate changes this century, including multiple meters of sea ... By looking at how the Earth,s climate responded to ... question raised by ongoing human-caused climate change: "What is ...
... Mellon University,s Roberto R. Gil and Rongchao Jin ... of infinitesimal gold nanoparticles, which could advance the ... drug development. Their approach offers a ... nanoparticles because it can determine whether the nanoparticles ...
... New York, NYDecember 7, 2011Thanks to a new ... be able to diagnose in their offices non-periodic ... Non-periodic arrhythmias include atrial and ventricular fibrillation, which ... can in some cases be life-threatening. ...
Cached Biology News:Paleoclimate record points toward potential rapid climate changes 2Paleoclimate record points toward potential rapid climate changes 3Paleoclimate record points toward potential rapid climate changes 4Carnegie Mellon researchers use NMR to determine whether gold nanoparticles exhibit 'handedness' 2Carnegie Mellon researchers use NMR to determine whether gold nanoparticles exhibit 'handedness' 3New Columbia engineering technique diagnoses non-periodic arrhythmias in a single heartbeat 2
(Date:8/21/2014)... including DESY scientists has observed tiny quantum vortices in ... the journal Science that the exotic vortices ... It is the first time that the quantum vortices, ... what is known as superfluid helium, have been detected ... says Andrey Vilesov of the University of Southern California, ...
(Date:8/21/2014)... August 21, 2014 ... has announced the addition of the  "Global ... their offering.       (Logo: http://photos.prnewswire.com/prnh/20130307/600769) ... therapy, is a means of replacing hormones ... the body. This type of therapy is ...
(Date:8/21/2014)... 21, 2014 Telomere Biosciences, LLC (Telomere ... "TELO-20 for Dogs" with Telomerase Activation Complex ... the world for dogs. Telomeres are the protective ... the body. A wealth of ground-breaking research by ... Science and Aging, including Nobel laureates, has demonstrated ...
(Date:8/21/2014)... Mass. , Aug. 21, 2014  Decision ... Brazil and ... The uptake of several newly approved agents, the ... this indication and the launch of emerging biologics ... markets. In particular, the emerging IL-5 inhibitors will ...
Breaking Biology Technology:Scientists observe quantum vortices in cold helium droplets 2Global Hormone Replacement Therapy Market 2014-2018: Key Vendors are Actavis, Bayer, Merck & Co, Novartis and Novo Nordisk 2Telomere Biosciences Announces: TELO-20 for Dogs, the World's First Telomere-Lengthening Supplement for Dogs, to Promote Healthy Aging and Longevity 2Telomere Biosciences Announces: TELO-20 for Dogs, the World's First Telomere-Lengthening Supplement for Dogs, to Promote Healthy Aging and Longevity 3Asthma Agents Currently Face a Suboptimal Coverage Environment in Brazil and Mexico, and as the Treatment Armamentarium Expands, Competitiveness Will Further Intensify 2Asthma Agents Currently Face a Suboptimal Coverage Environment in Brazil and Mexico, and as the Treatment Armamentarium Expands, Competitiveness Will Further Intensify 3
... Technologies, Inc., a leading,provider of innovative services ... today that Shabbir Anik, Ph.D.,will join the ... Officer. Dr.,Anik, the former President of Pharmaceutical ... Althea,s expansion of its product development,clinical trial ...
... advanced and powerful electron microscope on the planetcapable of ... for Electron Microscopy at McMaster University. , "We are ... of such a high calibre," says Gianluigi Botton, director ... Materials Science and Engineering, and the project,s leader. ...
... N.C., Oct. 20 With limited information ... support of Continuing,Medical Education activities, pharmaceutical, biotechnology ... understand the value of CME,support and strategies ... practitioner behaviors and patient outcomes. In the ...
Cached Biology Technology:Althea Technologies Appoints Dr. Shabbir Anik as Chief Executive Officer 2McMaster University unveils world's most advanced microscope 2Bio-Pharma Industry Improves Patient Outcomes Through Continuing Medical Education (CME) 2
... first instrument engineered to match the speed ... thousands of research centers worldwide. It uses ... are ideally suited for high-speed temperature cycling ... high surface-area-to-volume ratio. ,By combining glass capillary ...
... Antibody is a mouse monoclonal antibody ... 26 kDa glutathione-S-transferase (GST) domain from ... is suitable for detecting fusion proteins ... E. coli , yeast, mammalian, and ...
... at 470 nm; includes interface cable to S2000; ... into rack or desktop boxes The ... LED that produces either pulsed or continuous output ... for fluorescence measurements. The source is designed for ...
Sterile, Cell culture tested...
Biology Products: