Navigation Links
Apple or pear shape is not main culprit to heart woes -- it's liver fat
Date:12/4/2008

For years, pear-shaped people who carry weight in the thighs and backside have been told they are at lower risk for high blood pressure and heart disease than apple-shaped people who carry fat in the abdomen. But new findings from nutrition researchers at Washington University School of Medicine in St. Louis suggest body-shape comparisons don't completely explain risk.

In two studies, they report excess liver fat appears to be the real key to insulin resistance, cholesterol abnormalities and other problems that contribute to diabetes and cardiovascular disease. Having too much fat stored in the liver is known as nonalcoholic fatty liver disease.

"Since obesity is so much more common now, both in adults and in children, we are seeing a corresponding increase in the incidence of nonalcoholic fatty liver disease," says senior investigator Samuel Klein, M.D., the Danforth Professor of Medicine and Nutritional Science. "That can lead to serious liver disorders such as cirrhosis in extreme cases, but more often it tends to have metabolic consequences."

Klein, who heads the Division of Geriatrics and Nutritional Science and runs Washington University's Center for Human Nutrition, studied obese adolescents. They were divided into two groups: obese with excessive liver fat and those with no evidence of fatty liver disease. The groups were matched by age, sex, body mass index, body fat percentage and degree of obesity.

The researchers determined that children with fatty liver disease also had abnormalities in glucose and fat metabolism, including lower levels of HDL cholesterol, the so-called good cholesterol. Those without a fatty liver did not have markers of metabolic problems. Whether shaped like pears or apples, it was fat in the liver that influenced metabolic risk.

"Abdominal fat is not the best marker for risk," says Klein, who also directs the Nutrition Support Service at Barnes-Jewish Hospital. "It appears liver fat
'/>"/>

Contact: Jim Dryden
jdryden@wustl.edu
314-286-0110
Washington University School of Medicine
Source:Eurekalert

Page: 1 2

Related biology news :

1. Surprise in the organic orchard -- a healthier worm in the apple
2. Naturally-occurring apple compounds reduce risk of pancreatic cancer
3. Popular apple variety harbors unusual cell growth
4. Comparing apples and pears
5. Kazak apple research key to preventing blue mold
6. Carnegie Mellon developing automated systems to enable precision farming of apples, oranges
7. Facial attraction -- choice of sexual partner shaped the human face
8. Shape encoding may start in the retina
9. Grant supports study of abnormal ring-shaped chromosomes
10. Secure Services Corp. Achieves Milestone in United States Identity Protection with the Launch of the SSC SHAPE Card Management Solution
11. How cells keep in shape
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2014)... Entomological Society of America (ESA) has elected ten new ... a Fellow acknowledges outstanding contributions to entomology in one ... administration. The following Fellows will be recognized during Entomology ... be held November 16-19, 2014 in Portland, Oregon. , ... with the Department of Plant, Soil and Entomological Sciences ...
(Date:7/30/2014)... -- A study of dominance in female baboons suggests that ... ties with mom, and to have lots of supportive sisters. ... size or strength, but by the rank of her mother ... daughter will be. For this reason, dominance rank in female ... to high-ranking mothers are guaranteed a good spot in the ...
(Date:7/30/2014)... New York , July 30, 2014 /PRNewswire/ ... research on Global Government Biometric Systems Market ... The Global Biometric Systems Market 2014-2024" ... biometric systems market over the next ten years, ... using detailed market size forecasts. To ...
Breaking Biology News(10 mins):Entomological Society of America recognizes 2014 fellows 2Entomological Society of America recognizes 2014 fellows 3Entomological Society of America recognizes 2014 fellows 4Entomological Society of America recognizes 2014 fellows 5Entomological Society of America recognizes 2014 fellows 6Entomological Society of America recognizes 2014 fellows 7Entomological Society of America recognizes 2014 fellows 8Entomological Society of America recognizes 2014 fellows 9Entomological Society of America recognizes 2014 fellows 10Entomological Society of America recognizes 2014 fellows 11Entomological Society of America recognizes 2014 fellows 12Entomological Society of America recognizes 2014 fellows 13Entomological Society of America recognizes 2014 fellows 14Entomological Society of America recognizes 2014 fellows 15Entomological Society of America recognizes 2014 fellows 16Entomological Society of America recognizes 2014 fellows 17Supportive moms and sisters boost female baboon's rank 2Supportive moms and sisters boost female baboon's rank 3Global Government Biometric Systems Market Size, Share, Trends and Forecasts 2014-2024 Available Online by Researchmoz.us 2Global Government Biometric Systems Market Size, Share, Trends and Forecasts 2014-2024 Available Online by Researchmoz.us 3Global Government Biometric Systems Market Size, Share, Trends and Forecasts 2014-2024 Available Online by Researchmoz.us 4Global Government Biometric Systems Market Size, Share, Trends and Forecasts 2014-2024 Available Online by Researchmoz.us 5Global Government Biometric Systems Market Size, Share, Trends and Forecasts 2014-2024 Available Online by Researchmoz.us 6Global Government Biometric Systems Market Size, Share, Trends and Forecasts 2014-2024 Available Online by Researchmoz.us 7Global Government Biometric Systems Market Size, Share, Trends and Forecasts 2014-2024 Available Online by Researchmoz.us 8Global Government Biometric Systems Market Size, Share, Trends and Forecasts 2014-2024 Available Online by Researchmoz.us 9Global Government Biometric Systems Market Size, Share, Trends and Forecasts 2014-2024 Available Online by Researchmoz.us 10
... have called for the guidance documents for the implementation ... updated. The consensus among the scientists and stakeholders who ... for Environmental Research (UFZ) in November was that the ... be taken further. The experts can already see that ...
... NC Scientists at Duke University have created the first ... say a modern-day Rosetta stone a form of artificial ... success. The study revealed four times as many ... on the cover of the December 3 issue of Genome ...
... 8 million people at high risk for advanced age-related ... the experimental drug, endostatin, may be the cure. A ... The FASEB Journal, describes how giving endostatin to mice ... the eye, which is ultimately why the disease causes ...
Cached Biology News:Further development of Water Framework Directive necessary 2Further development of Water Framework Directive necessary 3Duke scientists map imprinted genes in human genome 2Duke scientists map imprinted genes in human genome 3New treatment for age-related macular degeneration within sight 2
(Date:7/30/2014)... 30, 2014  Replikins Ltd. today released new data ... virus. Before the current outbreaks, the mean Ebola Reston ... acids) between 1995 and 2002 was 1.1; the mean ... and sixteen-fold in 2013, thus predicting the current outbreaks ... has been shown to be able to predict outbreaks ...
(Date:7/30/2014)... NewYork (PRWEB) July 30, 2014 ... the increase of personal health expenditure as well ... health care system, China diagnostic reagent industry has ... occupy over 90%. In 2013, Chinese in vitro ... RMB16.61 billion came from in vitro diagnostic reagents. ...
(Date:7/30/2014)... 2014  Orexigen Therapeutics, Inc. (Nasdaq: OREX ... List of Outstanding Issues (LOI) from the European Medicines ... for the NB32 Marketing Authorization Application (MAA). NB32 (naltrexone ... drug candidate being evaluated for weight loss. ... point were adequately addressed by the Company based in ...
(Date:7/30/2014)... 30, 2014  RXi Pharmaceuticals Corporation (NASDAQ: ... focused on discovering, developing and commercializing innovative ... RNA-targeted technologies, today announced that their third ... the reduction of recurrence of hypertrophic scars ... initiated. Logo - http://photos.prnewswire.com/prnh/20130917/NE80755LOGO ...
Breaking Biology Technology:China Diagnostic Reagent Industry Report, 2013-2016 | Researchmoz 2China Diagnostic Reagent Industry Report, 2013-2016 | Researchmoz 3Orexigen Receives CHMP Day 180 List of Outstanding Issues 2Orexigen Receives CHMP Day 180 List of Outstanding Issues 3RXi Pharmaceuticals Expands Clinical Program with Initiation of Third Phase 2a Study with RXI-109 for Treatment of Hypertrophic Scars 2RXi Pharmaceuticals Expands Clinical Program with Initiation of Third Phase 2a Study with RXI-109 for Treatment of Hypertrophic Scars 3RXi Pharmaceuticals Expands Clinical Program with Initiation of Third Phase 2a Study with RXI-109 for Treatment of Hypertrophic Scars 4RXi Pharmaceuticals Expands Clinical Program with Initiation of Third Phase 2a Study with RXI-109 for Treatment of Hypertrophic Scars 5
... - GeneNews Limited (TSX: GEN),a company focused on ... sample for the early detection of diseases and ... System,which covers the design and development of in-vitro ... colorectal disease status in a laboratory,setting, has met ...
... provider of,ion channel testing services for drug discovery ... expanding line of services in booth 2504 at,the ... Washington.,New FDA Critical Path safety profiling tools include ... ChanTest designed to,complement the FDA and ICH S7A ...
... Beckman Coulter,Inc. (NYSE: BEC ), a leading ... and innovate complex biomedical testing,announced today that Paul ... Business Development, will present at the 2008 Bear ... at 4:00 a.m.,(ET)., (Logo: http://www.newscom.com/cgi-bin/prnh/20031202/BECLOGO ), ...
Cached Biology Technology:GeneNews receives ISO 13485 accreditation 2ChanTest to Highlight Expanded Ion Channel Testing Services for Preclinical Safety at ToxExpo, Including the World's Largest Catalog of Validated Ion Channels, Booth 2504 2Beckman Coulter to Present at the 2008 Bear Stearns London Healthcare Conference 2
... Microsphere/Microarray Stabilizer is a is a bovine ... This product is an aqueous solution that ... (phosphate buffered saline), pH 6.6 - 7.2. ... 0.02% methylisothiazolone and 0.02% bromonitrodioxane as a ...
... aqueous-based mounting medium designed for the ... is especially recommended when using tracers ... It can also be used with ... (FITC), Rhodamine (TMRITC) and Texas Red. ...
...
... Product Rabbit polyclonal to JNK1 (phospho ... mapping to an internal domain containing phosphorylated T183/Y185. ... Mouse and Rat. Not yet tested in other ... of several subgroups, including the ERK, JNK, and ...
Biology Products: