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Antimicrobial sutures reduce infections in brain shunt surgery, study finds
Date:7/25/2008

hese studies were prospective, randomized and double-blinded.

"In animal trials sutures coated with the antimicrobial triclosan have been shown to reduce the number of bacteria adhering to sutures, but only one study has been published to date on their effect in preventing surgical site infection, so we decided to conduct our own trial," he said.

"Our results showed that using antimicrobial sutures reduced infection risk by 16 percent."

Antibiotic-impregnated shunts, which are used in some surgeries, have several limitations, said Rozzelle: "They don't provide complete protection, they can't be used in patients who are allergic to the antibiotics and they are a lot more expensive than non-impregnated shunts."

"Closing wounds with antimicrobial sutures may reduce infections in procedures implanting other devices, such as pacemakers and neurostimulators, pumps that deliver pharmaceuticals and shunts elsewhere in the body," he said.

Rozzelle and colleagues are planning to conduct a larger randomized controlled trial to confirm their initial findings.


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Contact: Lois Baker
ljbaker@buffalo.edu
716-645-5000 x1417
University at Buffalo
Source:Eurekalert

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