Navigation Links
Antifungal compound found on tropical seaweed has promising antimalarial properties
Date:2/21/2011

potent antifungal compounds. In laboratory testing, graduate student Amy Lane found that these bromophycolide compounds effectively inhibited the growth of Lindra thalassiae, a common marine fungus.

"The alga is marshalling its defenses and displaying them in a way that blocks the entry points for microbes that might invade and cause disease," Kubanek said. "Seaweeds don't have immune responses like humans do. But instead, they have some chemical compounds in their tissues to protect them."

Though all the seaweed they studied was from a single species, the researchers were surprised to find two distinct groups of antifungal chemicals. From one seaweed subpopulation, dubbed the "bushy" type for its appearance, 23 different antifungal compounds were identified. In a second group of seaweed, the researchers found 10 different antifungal compounds all different from the ones seen in the first group.

In the DESI-MS technique, a charged stream of polar solvent is directed at the surface of a sample under study at ambient pressure and temperature. The spray desorbs molecules, which are then ionized and delivered to the mass spectrometer for analysis.

"Our collaborative team of researchers from the Department of Biomedical Engineering and the College of Sciences has worked within the Bioimaging Mass Spectrometry Center at Georgia Tech to better understand the mechanisms of chemical defenses in marine organisms," said Fernandez. "This is an example of cross-cutting interdisciplinary research that characterizes our institute."

Kubanek is hopeful that other useful compounds will emerge from the study of signaling compounds in the coral reef community.

"In the natural world, we have seaweed that is making these molecules and we have fungi that are trying to colonize, infect and perhaps use the seaweed as a substrate for its own growth," Kubanek said. "The seaweed uses these molecules to try to prevent the fungus
'/>"/>

Contact: John Toon
jtoon@gatech.edu
404-894-6986
Georgia Institute of Technology Research News
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. Diverse wheat tapped for antifungal genes
2. Lavender oil has potent antifungal effect
3. Duke team finds compounds that prevent nerve damage
4. Argonne scientists peer into heart of compound that may detect chemical, biological weapons
5. Discovery of natural compounds that could slow blood vessel growth
6. LSUHSC awarded patent for compound inhibiting cancer and other diseases
7. Resveratrol, red wine compound linked to health, also found in dark chocolate and cocoa
8. Design of a compound that stabilizes the main natural suppressor of tumors
9. New $11 million center to speed production of new compounds for drug discovery
10. 3-substituted indolones as novel therapeutic compounds for neurodegenerative conditions
11. Scripps research scientists identify compounds for stem-cell production from adult cells
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Antifungal compound found on tropical seaweed has promising antimalarial properties
(Date:8/27/2014)... A growing number of studies have shown ... the pathogenesis of Parkinson,s disease. Previous studies ... Medical University in China have shown that ... injury, reduced divalent metal transporter 1 expression, ... substantia nigra of rotenone-induced Parkinson,s disease rats. ...
(Date:8/27/2014)... hours ago the Happy Camp Complex of fires had ... July complex had consumed 35,530 as of eight hours ... the Happy Camp Ranger District of the Klamath National ... August 11, 2014. All but three of those fires ... list of contained fires and their size at containment: ...
(Date:8/27/2014)... State University have found that century-old museum specimens hold clues ... pest that can weaken and kill trees and the ... insect populations increase on oak and maple trees in warmer ... also increase with global warming," says Dr. Elsa Youngsteadt, a ... paper on the work. , "More scale insects would be ...
Breaking Biology News(10 mins):Happy Camp and July Fire Complexes in California 2Museum specimens, modern cities show how an insect pest will respond to climate change 2
... National Institute of General Medical Sciences (NIGMS), part of ... million for grants in scientific areas it identified as ... to stimulate biomedical research and the economy using funds ... Act). "The GO grants fund projects that promise ...
... release is available in German . , ... instrument wouldn,t be a bad thing. It could help to ... measure. However, it must do so constructively. In order to ... just imagination, physicists at the Max Planck Institute for Astrophysics ...
... scientists have succeeded in producing the polymers used for ... of fossil fuel based chemicals. This groundbreaking research, which ... plastics, is published in two papers in the journal ... 50th anniversary. Polymers are molecules found in ...
Cached Biology News:NIGMS invests in scientific Grand Opportunities with Recovery Act funds 2NIGMS invests in scientific Grand Opportunities with Recovery Act funds 3Visual assistance for cosmic blind spots 2Visual assistance for cosmic blind spots 3Visual assistance for cosmic blind spots 4Bioengineers succeed in producing plastic without the use of fossil fuels 2
(Date:8/27/2014)... Flagship Biosciences LLC, a leading provider of ... medical device industries, has announced a laboratory and office ... consolidated its histology and tissue analysis operations from separate ... north of Denver. The new addresses are: , ... 100, Westminster, CO 80021 , Tissue Image Analysis Lab, ...
(Date:8/27/2014)... , Aug. 27, 2014 Research and ... Stable Isotope Ratio Mass Spectrometer Industry Report 2014" ... Stable Isotope Ratio Mass Spectrometer Industry Report 2014 is ... of the global isotope ratio mass spectrometer industry. ... industry including definitions, classifications, applications and industry chain structure. ...
(Date:8/27/2014)... Tris Pharma, a specialty pharmaceutical company focused ... it has been selected as an award winner in ... Awards for Excellence competition in the Business Expansion ... judges from SCORE (Counselors to America,s Small Business) and ... at a gala event to be held on October ...
(Date:8/27/2014)... Boca Raton, FL (PRWEB) August 27, 2014 ... that are applied through the use of a handheld ... consumers across the United States. , The brand ... care unit. BIOEQUA researchers were surprised to learn that ... to be made extremely small and delivered directly to ...
Breaking Biology Technology:Flagship Biosciences Announces Relocation and Expansion 2Global Stable Isotope Ratio Mass Spectrometer Industry Report 2014 2Tris Pharma Selected as an award winner in the New Jersey Business & Industry Association's 2014 Awards for Excellence 2BIOEQUA'S EQUA ESSENTIAL Product Line Redefines Skin Care & Now Available in America 2
... to bring about a consolidated manufacturing management platform, ... agreement to buy Datasweep, Inc. , a ... of the transaction, were not disclosed. , ,Located ... customers in the pharmaceutical, high-tech electronics, automotive and ...
... Paragon Development Systems (PDS) is ... integrated solution for medium-sized organizations seeking information ... businesses to integrate communications, create shared environments, ... consolidate storage and servers, providing greater freedom ...
... Two UW-Madison computer science professors, Paul ... named to the National LambdaRails Networking Researching Council (NNRC), ... fiber optic networks research goals. , ,The National ... across the country, which over the past three years ...
Cached Biology Technology:Two UW-Madison professors named to National LambdaRail Networking Research Council 2
... pulsed field separations of DNA larger than 2, ... megabase pairs. This agarose has the highest gel strength of any ... ... ...
Liquid. PBS containing 10 mM NaN 3 . AVOID FREEZE/THAW CYCLES. Recognizes α1, 2, 3, 5, 6 and 7 subunits of 20S proteasome. ...
Mouse monoclonal antibody to Lats2....
... Membrane Protein 2, Synaptobrevin 2). ... homology with any other known ... expected that the antibody will ... multata and bovine due to ...
Biology Products: