Navigation Links
Antifungal compound found on tropical seaweed has promising antimalarial properties
Date:2/21/2011

A group of chemical compounds used by a species of tropical seaweed to ward off fungus attacks may have promising antimalarial properties for humans. The compounds are part of a unique chemical signaling system that seaweeds use to battle enemies and that may provide a wealth of potential new pharmaceutical compounds.

Using a novel analytical process, researchers at the Georgia Institute of Technology found that the complex antifungal molecules are not distributed evenly across the seaweed surfaces, but instead appear to be concentrated at specific locations possibly where an injury increases the risk of fungal infection.

A Georgia Tech scientist will report on the class of compounds, known as bromophycolides, at the annual meeting of the American Association for the Advancement of Science (AAAS) Feb. 21, 2011 in Washington, D.C. The research, supported by the National Institutes of Health, is part of a long-term study of chemical signaling among organisms that are part of coral reef communities.

"The language of chemistry in the natural world has been around for billions of years, and it is crucial for the survival of these species," said Julia Kubanek, an associate professor in Georgia Tech's School of Biology and School of Chemistry and Biochemistry. "We can co-opt these chemical processes for human benefit in the form of new treatments for diseases that affect us."

More than a million people die each year from malaria, which is caused by the parasite Plasmodium falciparum. The parasite has developed resistance to many antimalarial drugs and has begun to show resistance to artemisinin today's most important antimalarial drug. The stakes are high because half of the world's population is at risk for the disease.

"These molecules are promising leads for the treatment of malaria, and they operate through an interesting mechanism that we are studying," Kubanek explained. "There are only a couple of drugs left
'/>"/>

Contact: John Toon
jtoon@gatech.edu
404-894-6986
Georgia Institute of Technology Research News
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. Diverse wheat tapped for antifungal genes
2. Lavender oil has potent antifungal effect
3. Duke team finds compounds that prevent nerve damage
4. Argonne scientists peer into heart of compound that may detect chemical, biological weapons
5. Discovery of natural compounds that could slow blood vessel growth
6. LSUHSC awarded patent for compound inhibiting cancer and other diseases
7. Resveratrol, red wine compound linked to health, also found in dark chocolate and cocoa
8. Design of a compound that stabilizes the main natural suppressor of tumors
9. New $11 million center to speed production of new compounds for drug discovery
10. 3-substituted indolones as novel therapeutic compounds for neurodegenerative conditions
11. Scripps research scientists identify compounds for stem-cell production from adult cells
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Antifungal compound found on tropical seaweed has promising antimalarial properties
(Date:7/9/2014)... in which animals can be found, concern mounts over ... increased range for a host mean new territory for ... team of UC Santa Barbara scientists, including parasitologists Ryan ... the Journal of Biogeography , Hechinger, Kuris and ... happen: Hosts may actually lose their parasites when the ...
(Date:7/9/2014)... Tampa, Fla. (July 9, 2014) Emerging fungal ... any other parasitic group, causing population declines of ... from the University of South Florida published in ... amphibians can acquire behavioral or immunological resistance to ... population declines. , "Acquired resistance is important ...
(Date:7/9/2014)... critically ill children with traumatic injuries have identified ... likely to develop a hospital-acquired infection. The study, ... published online in June in the journal ... that could lead to the clinical implementation of ... or reverse immune system damage following critical illness ...
Breaking Biology News(10 mins):Not at home on the range 2Not at home on the range 3Not at home on the range 4USF study: Amphibians can acquire resistance to deadly fungus 2Immune function predicts infection risk among child trauma patients 2Immune function predicts infection risk among child trauma patients 3
... 2010) In the Opening Session of the American ... AAPS President Danny D. Shen, Ph.D., presented the following ... pharmaceutical sciences: Excellence in Ligand-Binding Assay Award ... ANP Technologies, Inc.: Ray Yin; Yli Vallejo; Jing Pan, ...
... what impatiens to plant in your yard, a recent study ... Cajun Carmine, that is if you want fewer insects in ... impatiens attract more thrips than others was one of the ... off by flowers are actually complex compounds known as plant ...
... has been constructed by researchers at the Virginia ... gamma-proteobacteria, a large group of medically and scientifically ... and other disease-causing organisms.* By building powerful phylogenetic ... and differences between the make-up of many different ...
Cached Biology News:AAPS announces 2010 NBC award winners 2When plants attract bugs, it may be their own fault 2When plants attract bugs, it may be their own fault 3New 'Tree of Life' established for one of the largest groups of bacteria 2New 'Tree of Life' established for one of the largest groups of bacteria 3
(Date:1/14/2014)... 14, 2014 As pet owners drew up their lists of ... wrote: "Take better care of my furry companion." Nowadays there are ... top-brand carrying cases to take the little canine or feline darlings ... compelled to buy some pricey toys at the pet store. But ...
(Date:1/14/2014)... Jan. 14, 2014 The largest international professional ... plants and therapeutic derivatives thereof has endorsed an ... researchers about the challenges of adulterated herb and ... The Society for Medicinal Plant ...
(Date:1/14/2014)... (PRWEB) January 14, 2014 iLab Solutions, the ... as the new Director of Product Strategy. In this role, ... as iLab sub-teams to guide in the development of iLab ... provides the maximum possible benefit to the scientific community by ...
(Date:1/14/2014)... , Jan. 14, 2014  RXi Pharmaceuticals Corporation ... developing and commercializing innovative therapies addressing major unmet ... it received the Notice of Allowance from the ... unique self-delivering RNAi compounds (sd-rxRNA®), for the treatment ...
Breaking Biology Technology:New Year's Resolution: Give Pets the Gift of Top-Notch Health Care 2World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 2World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 3World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 4World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 5World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 6World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 7World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 8iLab Solutions Announces Michelle Detwiler as the New Director of Product Strategy 2RXi Pharmaceuticals Receives US Notice of Allowance for a Key Patent Relating to its Self-Delivering Technology with sd-rxRNAs targeting CTGF, including RXI-109, for the Treatment of Fibrotic Disorders 2RXi Pharmaceuticals Receives US Notice of Allowance for a Key Patent Relating to its Self-Delivering Technology with sd-rxRNAs targeting CTGF, including RXI-109, for the Treatment of Fibrotic Disorders 3
... New Haven, Conn. A study by Yale researchers offers ... among individuals suggesting that it is due less to ... that cause extended segments of the human genome to be ... focus for identifying genetic differences has traditionally been on point ...
... As the sizes of sensor networks and mobile devices ... a growing need for suitable power sources. Because even ... in nanoscale devices, scientists are exploring nanosize systems that ... the University of Illinois have shown that a single ...
... ST. LOUIS, Sept. 27 Sigma-Aldrich (Nasdaq:,SIAL) is ... been named the,Vice President of R&D for the ... this role, he will help expand Sigma-Aldrich,s,leadership position ... life science researchers. Sullivan has been involved with ...
Cached Biology Technology:Individual differences caused by shuffled chunks of DNA in the human genome 2Individual differences caused by shuffled chunks of DNA in the human genome 3Nanowire generates power by harvesting energy from the environment 2Sigma-Aldrich Names Patrick Sullivan New VP of Research and Development for Research Biotech 2
Rabbit polyclonal to Staphylococcus Enterotoxin E (Biotin) ( Abpromise for all tested applications)....
Rabbit polyclonal to Peptide E ( Abpromise for all tested applications)....
... siSolutions siRNA Custom Synthesis ... effective duplex RNA to knockdown ... 21-mers (19 RNA base pairs ... recently-published 27-mers, or other lengths ...
... first fully genetically encoded fluorescent sensor capable ... peroxide (H2O2), one of the main ROS ... of yellow fluorescent protein inserted into the ... (OxyR-RD), HyPer demonstrates submicromolar affinity to H2O2 ...
Biology Products: