Navigation Links
Antiepileptic drug use while pregnant impacts early child development
Date:7/17/2013

Children whose mothers took antiepileptic drugs (AEDs) while pregnant are at increased risk of early development issues, according to a new study published in Epilepsia, a journal published by Wiley on behalf of the International League Against Epilepsy (ILAE). Results of the study suggest that children exposed to AEDs in the womb were at risk for difficulties with motor development, language skills, social skills, and autistic traits compared to children whose mothers did not take anti-seizure medications.

Medical evidence suggests that epilepsy is fairly common in women of childbearing years, with the use of AEDs during pregnancy ranging from 0.2% to 0.5%. Studies have shown that children whose mothers have epilepsy are at increased risk of birth defects (congenital malformations)mainly thought to be caused by use of older generation AEDs during pregnancy. However, there is less understanding of AED effects on cognition during development, and there is a need for more evidence regarding long-term outcomes of children exposed to anti-seizure medication in utero.

A research team, led by Dr. Gyri Veiby from Haukeland University Hospital in Bergen, Norway, studied children from the Norwegian Mother and Child Cohort Study. From 1999 through 2008, researchers recruited mothers at 13-17 weeks of pregnancy; those mothers subsequently reported motor development, language skills, social skills and autistic traits of their children at 18 months (61,351 children) and 36 months (44,147 children). Risk of adverse outcomes was determined in children according to epilepsy in the mother or father, and with or without AED exposure in the womb.

Results show that 333 children were exposed to AEDs in the womb. At 18 months of age, the children exposed to AEDs in utero had increased risk of abnormal gross motor skills and autistic traits. Analysis of AED-exposed children at 36 months revealed an increase of abnormal scores for gross motor skill
'/>"/>

Contact: Dawn Peters
sciencenewsroom@wiley.com
781-388-8408
Wiley
Source:Eurekalert

Page: 1 2

Related biology news :

1. Eating junk food while pregnant may make your child a junk food addict
2. Libertarian paternalism and school lunches: Guiding healthier behavior while preserving choices
3. Protein filmed while unfolding at atomic resolution
4. Music with dinner: Whales sing during foraging season, not just while breeding
5. Multi-tasking whales sing while feeding, not just breeding
6. New process doubles production of alternative fuel while slashing costs
7. Ultrasound idea: Prototype NIST/CU bioreactor evaluates engineered tissue while creating it
8. Pregnant women with high celiac disease antibodies are at risk for low birth weight babies
9. Study reveals risk factors for blood clots in pregnant and postnatal women
10. Progesterone may be why pregnant women are more vulnerable to certain infections
11. Few pregnant women treated for sexually transmitted infections
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/29/2014)... cell,s nucleus, chromosomal DNA is tightly bound to ... call chromatin. Until about two decades ago, histones ... packing material around which the glamorous DNA strands ... greater appreciation for how DNA/histone interactions govern gene ... institutions studying the sequence of the genome from ...
(Date:8/29/2014)... the Tibetan plateau -- the largest topographic anomaly above ... its profound effect on climate and its reflection of ... Bulletin , Katharine Huntington and colleagues employ a cutting-edge ... and fossil snail shells to investigate the uplift history ... Views range widely on the timing of surface uplift ...
(Date:8/28/2014)... (ESA) is pleased to announce the selection of Dr. ... Honorary Membership acknowledges those who have served ESA for ... affairs of the Society that has reached an extraordinary ... ESA Governing Board and then voted on by the ... Awards Ceremony at Entomology 2014, ESA,s Annual Meeting in ...
Breaking Biology News(10 mins):'K-to-M' histone mutations: How repressing the repressors may drive tissue-specific cancers 2'K-to-M' histone mutations: How repressing the repressors may drive tissue-specific cancers 3Snails tell of the rise and fall of the Tibetan Plateau 2Snails tell of the rise and fall of the Tibetan Plateau 3Snails tell of the rise and fall of the Tibetan Plateau 4Snails tell of the rise and fall of the Tibetan Plateau 5Snails tell of the rise and fall of the Tibetan Plateau 6Snails tell of the rise and fall of the Tibetan Plateau 7Fred Baxendale selected as Honorary Member of the Entomological Society of America 2
... Registration is now open to the press for the ... be held August 1-6, 2010 in Pittsburgh. The meeting, which ... the challenge for our future," draws a critical combination of ... explore the causes and consequences of global warming and to ...
... - Proper and timely burning of some Eastern U.S. forests ... range of species, a Purdue University report shows. Dogwood ... deep in the soil and depositing it on the forest ... source of nutrition for a variety of species in a ...
... less healthy diets through adolescence than their peers who do not ... ten-year study showed that girls who drank soda at age five ... the duration of the study, which ended at age 15. Girls ... certain nutritional requirements, but their diets were healthier. The difference ...
Cached Biology News:Ecological Society of America explores global warming at its 95th Annual Meeting 2Ecological Society of America explores global warming at its 95th Annual Meeting 3Fire may be key to reviving dogwood trees in Eastern forests 2Early consumption of soda indicator of unhealthy diet 2Early consumption of soda indicator of unhealthy diet 3
(Date:8/28/2014)...   SunTrust Robinson Humphrey (STRH) today ... its equity research team in biotechnology and oilfield ... equity research demonstrates our commitment to providing our ... their investment decision making," said Biff Woodruff ... to make significant investments in differentiated content at ...
(Date:8/28/2014)... A new market research report ... available from Strategic Consulting, Inc., the leading information ... Market Review, Fourth Edition: Global Review of Microbiology ... and compares microbiology test volumes, market values and ... Asia, and forecasts future volumes and market values ...
(Date:8/27/2014)... (PRWEB) August 27, 2014 Varian Medical ... expand its current Salt Lake City manufacturing facility and ... of Utah to ultimately create 1,000 new full time ... , “Utah is home to hardworking people with ... be credited with Varian’s success in the manufacturing of ...
(Date:8/27/2014)... , Aug. 27, 2014   MSC , a ... safety, today announced the appointment of Mary Beth ... With 28 years of experience preparing companies for rapid ... as Executive Vice President of Corporate Development and Healthcare. ... improvement business , as well as corporate strategy and ...
Breaking Biology Technology:SunTrust Robinson Humphrey Expands Equity Research in Healthcare and Energy 2SunTrust Robinson Humphrey Expands Equity Research in Healthcare and Energy 32 Billion Industrial Microbiology Tests Conducted for Product Quality and Safety Worldwide 22 Billion Industrial Microbiology Tests Conducted for Product Quality and Safety Worldwide 3Varian Medical Systems Groundbreaking on Facility Expansion Triggers Influx of New Jobs to Salt Lake 2Varian Medical Systems Groundbreaking on Facility Expansion Triggers Influx of New Jobs to Salt Lake 3MSC names Mary Beth Loesch President and CEO 2
... The Art of the Start: The Time-Tested, Battle-Hardened Guide ... director of Garage Technology Ventures, tells readers that instead ... be better off spending their time generating new customer ... a good message, but the delivery is biting and ...
... Mick Jagger said: I cant get no satisfaction. As soon as one ... Maslow must have had this in mind when he set up that ... care of (like food, shelter and a CTA bus card) only leads ... ladder until you finally have your hands on an iPod. , ,The ...
... $1.3 million for manufacturing Australian biotech offers new ... added to Nasdaq next Monday Modine extends contract ... for the use of electronic maintencance Critcare reports ... Governor Doyle to propose $1.3 million for manufacturing ,Wisconsin ...
Cached Biology Technology:Sarcasm and rainmaking advice coexist in The Art of the Start 2Sarcasm and rainmaking advice coexist in The Art of the Start 3Sarcasm and rainmaking advice coexist in The Art of the Start 4Sarcasm and rainmaking advice coexist in The Art of the Start 5How to solve the salary mystery 2How to solve the salary mystery 3How to solve the salary mystery 4Tech Digest (11/15/2004) 2
... Form: White powder Assay: 1.5 - 2.0 Bleomycin units/mg Identity ... On Drying: less than or equal to 6.0% Copper (Cu): ... : 55 - 70% B 2 : 25 - 32% ... to 90% B 4 : less than or equal to ...
... adamanteus venom Description: Phosphodiesterase I ... in studying nucleic acid structure ... hydrolyzes 5'-mononucleotides from 3'-hydroxy-terminated ribo-oligonucleotides ... I cleaves ADP-ribosylated proteins at ...
This spacer is required to use the Miniature FRENCH Pressure Cell (FA-003) with the Laboratory Press....
... MultiScribe Reverse Transcriptase is a recombinant ... transcriptase. MultiScribe Reverse Transcriptase is similar ... in its recommended usage. MuLV reverse ... polymerase that uses single-stranded RNA as ...
Biology Products: