Navigation Links
Anticancer compound found in American mayapple
Date:9/4/2009

VERONA, MSA common weed called American mayapple may soon offer an alternative to an Asian cousin that's been harvested almost to extinction because of its anti-cancer properties. The near-extinct Asian plant, Podophyllyum emodi, produces podophyllotoxin, a compound used in manufacturing etoposide, the active ingredient in a drug used for treating lung and testicular cancer. Podophyllyum emodi is a cousin of the common mayapple weed found in the United States.

Podophyllotoxin is found in Indian mayapple (Podophyllum emodii Wall.), American mayapple (Podophyllum peltatum L.), and other species. Podophyllotoxin and its derivatives are used in several commercially available pharmaceutical products such as the anticancer drugs etoposide, teniposide, and etopophos, which are used in the treatment of small-cell lung cancer, lymphoblastic leukemia, testicular cancer, and brain tumors. Podophyllotixin derivatives are also used for the treatment of psoriasis and malaria, and some are being tested for the treatment of rheumatoid arthritis. Currently, podophyllotoxin is produced commercially using the roots and rhizomes of Indian mayapple, an endangered species harvested from the wild in India, Pakistan, Nepal, and China.

Researchers at Mississippi State University and the University of Mississippi recently set out to identify American mayapple types with high podophyllotoxin content. Valtcho D. Zheljazkov and colleagues at Mississippi State University published the research results in HortScience. According to Zheljazkov; "The objective of this study was to estimate podophyllotoxin concentration in American mayapple across its natural habitats in the eastern United States and to identify high podophyllotoxin types that could be used for further selection and cultivar development."

Mayapple has been long been grown as a cash crop in Europe and Russia, but has never been introduced or domesticated in the
'/>"/>

Contact: michael W. Neff
mwneff@ashs.org
703-836-4606
American Society for Horticultural Science
Source:Eurekalert

Page: 1 2

Related biology news :

1. Certain anticancer agents could be harmful to patients with heart disease
2. Better beer: College team creating anticancer brew
3. New microsensor measures volatile organic compounds in water and air on-site
4. Naturally-occurring apple compounds reduce risk of pancreatic cancer
5. Chemical compound present in detergents produce bacteria alterations in agricultural soils
6. Synthetic compound promotes death of lung-cancer cells, tumors
7. Natural compound in broccoli could treat devastating genetic skin disorder
8. New form of compound stimulates research on hydrogen storage
9. Protein protects brain against compound in lead poisoning, liver disease
10. A compound extracted from olives inhibits cancer cells growth and prevents their appearance
11. UDs Bobev receives NSF Early Career Award for research on novel compounds of rare Earth metals
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... 2014  Automation is fundamentally transforming the travel ... at international borders. Over the past decade, ePassports, ... veteran travelers to self process through border control ... at an increasing number of airports, seaports, and ... According to Maxine Most , Principal at ...
(Date:12/11/2014)... DUBLIN , Dec. 09, 2014 Research ... http://photos.prnewswire.com/prnh/20130307/600769 ( http://www.researchandmarkets.com/research/9ql3kr/biometrics_market ) ... Market in India 2015-2019" report to their ... in this market is the adoption of multimodal ... one characteristic of an individual for verification and ...
(Date:12/10/2014)... 8, 2014 You,ve been here before: you desperately ... remember your password, site key or the answer to your ... grade teacher? Today, Hoyos Labs , ... that will finally put an end to the frustration that ... . 1U leverages a user,s smartphone to acquire his ...
Breaking Biology News(10 mins):Automated Border Control (ABC) Transforms the Global Travel Experience With More Than 2500 ABC eGates and APC Kiosks Deployed In Airports, Seaports, and Land Borders Worldwide 2Biometrics Market in India 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 2The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 3
... administered in combination with a short course of ... the most lethal form of the disease, according ... Institute of Infectious Diseases (USAMRIID). , In ... Institute of Allergy and Infectious Diseases (NIAID), investigators ...
... Insect Molecular Biology, today publishes its Honey Bee Genome ... the long-awaited Honey Bee Genome Sequence, published earlier this ... Genome Sequencing Project (HBGSP), a large scale communal project ... the National Human Genome Research Institute, is expected to ...
... 20 years studying a worm-shaped parasite too small to ... Hussey and his research team have found a way ... world's most destructive groups of plant pathogens. , Root-knot ... nematodes worldwide, said Hussey, a distinguished research professor in ...
Cached Biology News:Vaccine combined with short-term postexposure antibiotics protects monkeys from inhalational anthrax 2Vaccine combined with short-term postexposure antibiotics protects monkeys from inhalational anthrax 3Looking to a new era in bee research 2UGA scientists engineer root-knot nematode resistance 2
(Date:12/24/2014)... , Dec. 24, 2014   BioLife Solutions , ... manufacturer and marketer of proprietary clinical grade hypothermic ... precision thermal shipping products for cells and ... will hold its 2015 Annual Meeting of Stockholders on ... the expected date for the Annual Meeting represents a ...
(Date:12/24/2014)... Boston, MA (PRWEB) December 23, 2014 ... presentation, Dr. James L. Sherley, director of the Adult ... attention on an often overlooked and under appreciated unique ... “Asymmetric Self-Renewal by Distributed Stem Cells: Misunderstood in the ... his message to congress participants. He gave the ...
(Date:12/24/2014)... Long Island, New York (PRWEB) December 23, 2014 ... , and the Long Island Affiliate of ITRA Global, the ... economy’s slow but steady recovery. This is evidenced by ... and the strong stock market. Low energy costs have ... low. The only negative is the housing market remaining ...
(Date:12/24/2014)... The report expects global cell isolation and expansion ... provides a carefully analyzed data about the vital drivers, ... , Full Copy of Report @ http://bit.ly/1yUxy0T ... cell expansion will keep witnessing growth at an impressive ... be driven by rapid technological advancements, government funding and ...
Breaking Biology Technology:BioLife Solutions Sets Date for Annual Meeting of Stockholders 2Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 2Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 3Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 4ITRA Global Reports Long Island Is Out of Sync With The National Office Market 2ITRA Global Reports Long Island Is Out of Sync With The National Office Market 3The Cell Expansion Market is Expected to Reach $14.8 billion by 2019 - New Research Report by MarketsandMarkets 2The Cell Expansion Market is Expected to Reach $14.8 billion by 2019 - New Research Report by MarketsandMarkets 3
... and HONG KONG, May 25, 2011 SuperNova ... human and non-human health applications, today announced it ... Valley Association of Startup Entrepreneurs (SVASE) annual Launch: ... campus on Tuesday, June 7, 2011 at 1:15 ...
... from the National Physical Laboratory (NPL), in collaboration with ... of different thickness can be easily identified in ambient ... properties of graphene are usually only applicable to the ... the graphene sheets. Whilst synthesis of any number of ...
... BETHESDA, Md., May 24, 2011 Spherix ... biotechnology for therapy in diabetes, metabolic syndrome and ... services to food, supplement, biotechnology and pharmaceutical companies ... with NASDAQ listing rule 5550(a)(2), which concerns minimum ...
Cached Biology Technology:SuperNova Diagnostics® Selected to Present at Launch: Silicon Valley 2011 2Spherix Regains Compliance With NASDAQ Listing Rule 2
... is a multi-functional program that ... from a sequence file for ... sequencing, site-directed mutagenesis, and various ... temperature and secondary structure of ...
...
Kit contains: Bio-Rad Amplification Reagent, 2x Amplification Diluent, Streptavidin-HRP, Blocking Reagent, and Phosphate Buffered Saline....
...
Biology Products: