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Anti-tumor drugs tested by microfluidic device
Date:10/5/2010

ated.

Wu also said that, "Unlike conventional methods, the microfluidic device permits quantitative data to be obtained from individual cells; the device requires fewer numbers of cells and allows testing of amounts of reagents reduced by about 4 orders of magnitude. In a conventional 96-well plate study, each well is around 1 centimeter, while in our microchip device, each cell chamber has a dimension of hundreds of microns. Reducing the sample size has significant merit because in most cases, the biomolecules in use are extremely expensive, even in quantities in milligrams or less."

While this report concerns a test of five ladder channels on a single chip, higher throughputs should be possible, Wu stated. "This prototype system should be useful in the areas of biology and bioengineering, especially for discovering apoptosis-inducing agents," Wu concluded.


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Contact: Jason Bardi
jbardi@aip.org
301-209-3091
American Institute of Physics
Source:Eurekalert

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