Navigation Links
Anti-HIV therapy boosts life expectancy more than 13 years
Date:7/25/2008

BIRMINGHAM, Ala. The life expectancy for patients with human immunodeficiency virus (HIV) has increased by more than 13 years since the late 1990s thanks to advancements in antiretroviral therapy, according to researchers at the University of Alabama at Birmingham (UAB) and Simon Fraser University in Vancouver, British Columbia.

Improved survival has led to a nearly 40 percent drop in AIDS deaths among 43,355 HIV-positive study participants in Europe and North America, bolstering the call for improved anti-HIV efforts worldwide, the study authors said.

The study is published in the British medical journal The Lancet. It was compiled by The Antiretroviral Therapy Cohort Collaboration, which includes UAB, Simon Fraser University and more than a dozen other research sites around the world.

The authors looked at changes in life expectancy and mortality among the 43,355 HIV patients taking a cocktail of drugs called combination antiretroviral therapy (cART). Data was compiled from a total of 14 studies in Europe and North America.

"Since their introduction in 1996 cART regimens have become more effective, better tolerated and easier to follow," said Michael Mugavero, M.D., an assistant professor in UAB's Division of Infectious Diseases and a co-author on the study.

"We are now seeing the benefits of years of research, hard work and efforts to make these medications widely available. This has led to dramatic improvements in life expectancy, but patients who start cART with more advanced HIV infection do not have the same level of benefit," Mugavero said.

The new Lancet study found cART yielded a 13.8-year life-expectancy increase from 36.1 years in study participants who began therapy during the 1996-1999 period, to 49.9 years in participants who began therapy during the 2003-2005 period.

Despite the good results, the study found life expectancy for HIV patients is far lower on average than the general population, which includes all those with other chronic illnesses. For example, an HIV-positive patient starting cART at age 20 will live to 63, about 20 years shorter than the average life span of non-infected adults.

With nearly half of all patients diagnosed with advanced HIV infection, the life expectancy benefits of cART are not fully realized, said Mugavero and lead study author Robert Hogg, Ph.D., of Simon Fraser University. Improved AIDS testing and increased access to care is needed.


'/>"/>

Contact: Troy Goodman
tdgoodman@uab.edu
205-934-8938
University of Alabama at Birmingham
Source:Eurekalert  

Related biology news :

1. Researcher helping to pioneer medical therapy for Fragile X Syndrome presents latest findings
2. Mitochondrial cholesterol makes response to chemotherapy difficult in hepatic cancer
3. Prostate cancer vaccines more effective with hormone therapy
4. New oral angiogenesis inhibitor offers potential nontoxic therapy for a wide range of cancers
5. Caution on stem cell therapy
6. Potential therapy discovered for hypophosphatasia, a congenital form of rickets
7. UF researchers develop improved gene therapy agent
8. Gene therapy slows progression of fatal neurodegenerative disease in children
9. UC Davis stem researchers demonstrate safety of gene therapy using adult stem cells
10. Cell-based therapy shows promise in patients with Parkinsons disease
11. Cancer immunotherapy shows long-term promise in lung cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Anti-HIV therapy boosts life expectancy more than 13 years
(Date:5/16/2017)... , May 16, 2017  Veratad Technologies, LLC ( ... online age and identity verification solutions, announced today they ... Conference 2017, May 15 thru May 17, 2017, in ... and International Trade Center. Identity impacts ... and in today,s quickly evolving digital world, defining identity ...
(Date:4/18/2017)... April 18, 2017  Socionext Inc., a global expert in SoC-based ... edge server, the M820, which features the company,s hybrid codec technology. ... by Tera Probe, Inc., will be showcased during the upcoming Medtec ... show at the Las Vegas Convention Center ... Click here ...
(Date:4/11/2017)... -- Research and Markets has announced the addition of ... offering. ... market to grow at a CAGR of 30.37% during the period ... has been prepared based on an in-depth market analysis with inputs ... growth prospects over the coming years. The report also includes a ...
Breaking Biology News(10 mins):
(Date:8/15/2017)... NC (PRWEB) , ... August 15, 2017 , ... ... 2017, celebrating 10 years of successes helping medical technology companies and inventors develop and ... to a renowned full-service national engineering firm with a portfolio of clients in the ...
(Date:8/15/2017)... ... 15, 2017 , ... The Conference Forum and The Trout ... a series of upcoming panels and events. The partnership culminates with the 4th ... in New York City. , “With our experience in producing the Immuno-Oncology 360° NYC ...
(Date:8/14/2017)... ... 14, 2017 , ... The Conference Forum has confirmed the one-day ... on September 6, 2017 at the Marriott Copley Place in Boston, MA. , Returning ... and Regulatory Strategy, Pfizer Innovative Research Lab, Pfizer, who leads 19 industry speakers in ...
(Date:8/10/2017)... , ... August 09, 2017 , ... ... help the agriculture industry reach its ideal customers with the right message. Their ... , “As a Midwest company, we realize how crucial the agriculture industry is,” ...
Breaking Biology Technology: