Navigation Links
Annals of Internal Medicine tip sheet for Jan. 19, 2010, issue
Date:1/18/2010

1. Prescribed Opioids Associated with Significant Risk for Overdose

Prescriptions of some opioids, such as oxycodone, have increased significantly over the past decade. As long-term opioid therapy for chronic noncancer pain becomes more common, the deaths associated with opioids increase. Opioid overdose is among the most common causes of death nationwide. Researchers sought to determine the rate of opioid overdose in relation to an average prescribed daily opioid dose among patients receiving medically-prescribed, long-term opioid therapy. Researchers observed 9,940 adults receiving at least three opioid prescriptions for chronic noncancer pain within 90 days. Fifty-one of the 9,940 adults receiving long-term opioid therapy had one or more overdose events during follow-up. Six of those events were fatal. Most of the observed overdoses occurred in patients receiving lower opioid doses although risks for overdoses increased for patients receiving higher doses. Due to uncertainties regarding effectiveness and the risk for overdose, long-term opioid therapy should be prescribed carefully for noncancer pain. Researchers recommend that physicians closely monitor opioid patients, dose judiciously, and continually reevaluate the benefit of the drugs. A. Thomas McLellan, PhD., author of an editorial on the study and Deputy Director of the White House Office of National Drug Control Policy states, "The threat to patient safety is too great to allow current pain management and opioid prescribing practices to remain as they are."


2. Leptin Therapy Could Hold Key to Long-term Weight Loss

Hormone Helps to Regulate Energy Homeostasis, Neuroendocrine Function, and Metabolism

Leptin is a hormone that plays a central role in fat metabolism. Patients with genetic leptin deficiency are obese, and treatment with leptin leads to dramatic weight loss through decreased food intake and possible increased energy expenditure. H
'/>"/>

Contact: Angela Collom
acollom@acponline.org
215-351-2653
American College of Physicians
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Annals of the ESA selected as one of 100 most influential journals
2. Plants grow bigger and more vigorously through changes in their internal clocks
3. New research seeks to enhance quality and security of wireless telemedicine
4. Penn Veterinary Medicine report new strategy to create genetically-modified animals
5. SNM applauds NAS study showing need to restore federal nuclear medicine research funding
6. Gene-targeting pioneer Mario Capecchi shares 2007 Nobel Prize in Medicine
7. Professor Sir Martin Evans wins Nobel Prize for Medicine
8. 3 Columbia University Medical Center faculty elected to Institute of Medicine
9. In the laboratory, green tea proves a powerful medicine against severe sepsis
10. Telemedicine: Health alert via satellite
11. Study of African traditional medicine will begin world-first clinical trial
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/12/2015)... , March 12, 2015 WHEN:Tuesday, March ... Registration here: http://bit.ly/1G7Os0L . SPEAKERS: , Frost ... SeshagiriPhoto - http://photos.prnewswire.com/prnh/20150311/181111 Biometric ... to compete in several different markets and industries. ... currently witnessing an uptrend. Join ...
(Date:3/10/2015)... March 10, 2015 Transforming How ... "Personalized Medicine in Human Space Flight" by ... J. Goodwin , Ph.D. was recently featured by Springer ... two years. Specifically, "Personalized Medicine in Human ... papers published in 2013 and 2014 from Springer in ...
(Date:3/4/2015)... , Mar. 04, 2015 Research and Markets ... addition of the "Global Biometrics Market Forecast ... The market for biometric authentication systems ... around 14% till 2020 The driving ... increasing security needs, government projects and constant development ...
Breaking Biology News(10 mins):Biometrics Key to Future Growth in Healthcare, Retail and Financial Markets 2Biometrics Key to Future Growth in Healthcare, Retail and Financial Markets 3"Personalized Medicine in Human Space Flight" Listed Among Most Influential Papers of 2013 and 2014 2Global Biometrics Market Forecast and Opportunities, 2020 2Global Biometrics Market Forecast and Opportunities, 2020 3
... STM publisher Springer and Beijing Normal University Press ... Governance Project Series. The agreements for the first seven ... CEO Springer Science+Business Media, and Prof. Geng Yang, CEO ... The Integrated Risk Governance Project (IRG-Project) is supported by ...
... East region is expecting a demographic explosion in the number of ... 2020 it is expected that 25% of the population will be ... to 40%. This is a warning call for health ... a dramatic rise in age-related chronic diseases such as osteoporosis. ...
... LA JOLLA, CA May 10, 2012 Scientists at ... that act to block an enzyme that has been linked ... as some inflammation-promoted cancers. The new study, published ... new compounds that inhibit an important enzyme called PRMT1 (protein ...
Cached Biology News:Springer and the Beijing Normal University Press sign agreement on new book series 2New screening technique yields elusive compounds to block immune-regulating enzyme 2New screening technique yields elusive compounds to block immune-regulating enzyme 3
(Date:3/26/2015)... and CINCINNATI , ... plc (LSE: SHP, NASDAQ: SHPG ) and ... three-year, broad research collaboration for rare diseases. The goal ... novel therapies to treat rare diseases with high ... capabilities with Cincinnati Children,s research expertise. As a ...
(Date:3/26/2015)... March 26, 2015 ReliantHeart, Inc., an ... Transonic, a supplier of precision transit-time flow measurement solutions, ... greatly improve the efficiency of the HeartAssist5® ... patients to experience greater mobility and peace of mind. ... miniature flow board, will draw 1/6th of the power ...
(Date:3/26/2015)... 26, 2015 WriteResult, a premier provider ... from Yale University’s School of Public Health and New ... during a 4 month-long project. The goal of the ... income families with free access to fresh produce and ... health concerns like high blood pressure, diabetes and weight ...
(Date:3/25/2015)... TORONTO , March 25, 2015 /PRNewswire/ - SQI Diagnostics ... announced that, as a result of recent discussions with ... common shares of the Company, after dealing with certain ... and special meeting of shareholders on March 26, 2015 ... that the election of directors will take place when ...
Breaking Biology Technology:Shire and Cincinnati Children's Establish Rare Disease Research Collaboration 2Shire and Cincinnati Children's Establish Rare Disease Research Collaboration 3Shire and Cincinnati Children's Establish Rare Disease Research Collaboration 4Shire and Cincinnati Children's Establish Rare Disease Research Collaboration 5LVAD patients to have greater mobility and peace of mind through Transonic and ReliantHeart’s True Flow collaboration for the HeartAssist5® 2LVAD patients to have greater mobility and peace of mind through Transonic and ReliantHeart’s True Flow collaboration for the HeartAssist5® 3Yale and New Haven Farms Improving Patient Health with WriteResult's myPROpad™ 2Yale and New Haven Farms Improving Patient Health with WriteResult's myPROpad™ 3SQI Diagnostics Inc. Announces New Nominees to SQI Diagnostics Board and Adjournment of Meeting 2SQI Diagnostics Inc. Announces New Nominees to SQI Diagnostics Board and Adjournment of Meeting 3SQI Diagnostics Inc. Announces New Nominees to SQI Diagnostics Board and Adjournment of Meeting 4SQI Diagnostics Inc. Announces New Nominees to SQI Diagnostics Board and Adjournment of Meeting 5
... Extraction Reagent extracts cytosolic proteins ... while preserving their phosphorylation state. ... the CytoBuster Protein Extraction reagent, ... is compatible with Western blotting, ...
... to WinList come straight from the folks ... like automatic region positioning, N-Stat regions, and ... suggestions, thoughtful conversations, and careful design. Of ... on are still there, too. WinList leads ...
Ubiquitin-like protein 4A (Ubiquitin-like protein GDX). [Source:Uniprot/SWISSPROT;Acc:P11441] Antigen: Recombinant Protein Epitope Signature Tag (PrEST)....
AK6 Antibody...
Biology Products: