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Animal welfare scientists reveal infrequent and inconsistent acceptance of existing data by EPA to satisfy endocrine disruptor testing requirements
Date:11/1/2013

se of OSRI and direction by the Office of Management and Budget in approving the EPA's request to collect Tier 1 data that the agency accepts OSRI to the greatest extent possible, the study found that the EPA applied a rather narrow and limited approach to acceptance of OSRI. Most OSRI accepted in lieu of new testing either indicated a positive result or was produced using a study method that was identical or very similar to a Tier 1 or Tier 2 assay, even though the EPA said functionally equivalent studies would be considered. The OSRI analysis shows that results from Part 158 studies were accepted infrequently and that there were cases where literature studies were accepted for one chemical when the results were positive but rejected for another chemical evaluated in the study when the results were negative.

"Even with the EPA's planned integration of 21st -century toxicity-testing tools, such as computational toxicology methods and high throughput in vitro assays, into the EDSP for prioritization and screening purposes, OSRI will continue to play an important role in reducing the number of animals used in testing and in pretesting until such time when we can do away with animal testing completely," Bishop added.


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Contact: Tasgola Bruner
TasgolaB@peta.org
770-518-1675
People for the Ethical Treatment of Animals
Source:Eurekalert

Page: 1 2 3

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