Navigation Links
Animal models that help translate regenerative therapies from bench to bedside
Date:2/11/2010

New Rochelle, NY, February 11, 2010Clinical testing and development of novel therapies based on advances in tissue engineering and regenerative medicine that will one day enable the repair and replacement of diseased or damaged human muscle, bone, tendons, and ligaments depends on the availability of good animal models. The highlights of a recent workshop that explored the need for and current status of animal models for musculoskeletal regenerative medicine are presented in a special issue of Tissue Engineering, Part B: Reviews, a peer-reviewed journal published by Mary Ann Liebert, Inc. (www.liebertpub.com) The issue is available free online (www.liebertpub.com/ten).

The production of specially engineered tissues to restore the function and viability of cartilage or meniscus in the knee, for example, or of degenerating intervertebral discs in the spine, will likely one day be commonplace. In the meantime, however, there is substantial need for better and standardized animal models for the development and testing of these innovative techniques. At the National Institutes of Health (NIH)-sponsored workshop "Translational Models for Musculoskeletal Tissue Engineering and Regenerative Medicine," leaders in the field described available models, outlined the unmet needs, and discussed the translational pathways for clinical testing and therapeutic use.

Mark Lee, PhD, and colleagues from the U.S. Food and Drug Administration (FDA, Rockville, MD) explained how the complexity of engineered tissue constructs, often containing a combination of cells, scaffolds, and other factors, creates challenges for product characterization and manufacturing. In their paper "Considerations for Tissue-Engineered and Regenerative Medicine Product Development Prior to Clinical Trials in the United States," they provide resources and recommendations to help product developers o
'/>"/>

Contact: Vicki Cohn
vcohn@liebertpub.com
914-740-2156
Mary Ann Liebert, Inc./Genetic Engineering News
Source:Eurekalert

Page: 1 2

Related biology news :

1. Animals cope with climate change at the dinner table
2. New on-off switch triggers and reverses paralysis in animals with a beam of light
3. NIFA awards funding for animal health and production research
4. Better food makes high-latitude animals bigger
5. Oral COTI-2 is effective in a second animal model of human pancreatic cancer
6. Animal behavioral studies can mimic human behavior
7. Roe of marine animals is best natural source of omega-3
8. ORAL COTI-2 IS EFFECTIVE IN AN ANIMAL MODEL OF HUMAN PANCREATIC CANCER
9. New on-off switch triggers and reverses paralysis in animals with a beam of light
10. Master regulator found for regenerating nerve fibers in live animals
11. Geologist analyzes earliest shell-covered fossil animals
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/14/2015)... OXFORD, Conn. , April 14, 2015 ... "Company"), a biometric authentication company focused on the growing ... has been nominated for the 2015 New York Design ... The Design100, New York City Design Awards are ... are based on over 2,500 ratings from the marketplace, ...
(Date:4/8/2015)... 8, 2015  Infinisource, a leading provider of SaaS-based ... Morpho, a leading supplier of biometric identification and ... market,s most advanced biometrically-enabled time clock, the companies ... clock is setting a bold, new standard for ... the small and mid-size employer. When connected to ...
(Date:4/2/2015)... GOTHENBURG, Sweden , April 2, 2015 ... for its touch fingerprint sensor FPC1025 from the distributor ... Deliveries will commence during Q2 2015 although the major ... 2015. The sensors will be used by smartphone manufacturers ... of 110 MSEK is included in the communicated revenue ...
Breaking Biology News(10 mins):NXT-ID's Wocket Smart Wallet Nominated for 2015 New York Design Awards in 'Product Design- Technology' 2NXT-ID's Wocket Smart Wallet Nominated for 2015 New York Design Awards in 'Product Design- Technology' 3iSolved Time Clock Offers Unmatched Accuracy due to Morpho Biometrics 2iSolved Time Clock Offers Unmatched Accuracy due to Morpho Biometrics 3Fingerprint Cards Receives Touch Fingerprint Sensor Order of SEK 110 Million 2
... Southampton Centre for Biomedical Research, established by the ... the University of Southampton, have been awarded 17m ... research facilities. The funding, which is ... NHS and university partnerships, has secured the future ...
... Ga. A research team from Rollins College in Florida ... the source of the coral-killing pathogen that causes white pox ... in the Caribbean, elkhorn coral was listed for protection under ... to white pox disease. The team,s findings have just been ...
... fecal material -- in particular, dog fecal material -- may ... Detroit,s wintertime air, says a new University of Colorado Boulder ... four Midwestern cities in the experiment, two cities had significant ... feces being the most likely source. "We found ...
Cached Biology News:Southampton researchers awarded $28 million to progress pioneering nutrition and respiratory research 2Human pathogen killing corals in the Florida Keys 2Human pathogen killing corals in the Florida Keys 3New CU-Boulder study reveals bacteria from dog feces in outdoor air of urbanized air 2New CU-Boulder study reveals bacteria from dog feces in outdoor air of urbanized air 3
(Date:4/24/2015)... (PRWEB) April 24, 2015 DryLet, ... use in applications such as animal waste reduction, ... oil reduction in wastewater treatment plants and restaurant ... exhibitor at the National Restaurant Association’s NRA Show ... , Representatives of the company will be available ...
(Date:4/24/2015)...  Pfenex Inc. (NYSE MKT: PFNX) a clinical-stage biotechnology ... high value and difficult to manufacture proteins, today announced ... shares of its common stock at a price to ... being offered, 2,610,000 are being offered by Pfenex and ... stockholders. Pfenex will not receive any proceeds from the ...
(Date:4/24/2015)... , April 24, 2015  Navitas Life Sciences is delighted ... Head of Clinical and Regulatory Services. Shalabh is a proven ... co-founder and CEO of Kinapse, as well as a Strategy ... Logo - http://photos.prnewswire.com/prnh/20150423/201261LOGO ... commented "I am delighted to welcome Shalabh into this ...
(Date:4/24/2015)... (PRWEB) April 24, 2015 Seoul ... technology for various applications in the lighting market. ... successful installations of this technology in emerging markets ... for a wide range of applications such as ... and decorative lighting. , First launched in 2005 ...
Breaking Biology Technology:DryLet to Showcase Bio-React at the National Restaurant Association’s NRA Show 2015 May 16-19, 2015 in Chicago, Illinois 2Pfenex Inc. Announces Pricing Of Follow-on Offering 2Shalabh Kumar Joins Navitas Life Sciences to Lead their Clinical and Regulatory Services Teams 2Acrich Technology from Seoul Semiconductor Adopted in Installations Worldwide 2
... announced that its executives will be speaking at the following,investor conferences, ... Credit Suisse Global Health Care Conference, Phoenix, AZ ... Mountain Time, Piper Jaffray Health Care ... 2, 2008 at 2.00 p.m. Eastern Time Accessing Webcasts, ...
... (Nasdaq: KOOL ), a leading supplier of innovative ... that it will be,participating in the Rodman & Renshaw ... The Company,s presentation by Dr. William Osgood, the Company,s ... am, Pacific Standard,Time), and will be held at the ...
... role in causing asthma. Now, a team of researchers ... noninvasively visualize in real-time eosinophil responses in the lungs ... asthma (experimental allergic airway inflammation); they hope that these ... of treatments (both old and new) for the disease. ...
Cached Biology Technology:Cepheid to Webcast Upcoming Financial Presentations 2ThermoGenesis Presentation at Rodman & Renshaw Conference 2
...
... as an internal standard for the quantification ... spectrometry. 5-OxoETE is a polyunsaturated keto acid ... human neutrophils. It stimulates cytosolic calcium levels ... nM. 5-OxoETE selectively stimulates the migration and ...
... System Delivers 4,600 to Over 3 Million ... System is capable of performing 4,600 to ... of the GenomeLab family of products*, this ... to 48 SNPs in each well of ...
... size markers are a mixture of Strep•Tag® ... 100 kDa. The markers provide precise size ... staining with Coomassie blue. Because each of ... the markers can also be detected by ...
Biology Products: