Navigation Links
Animal cells can communicate by reaching out and touching, UCSF team discovers
Date:1/2/2014

In a finding that directly contradicts the standard biological model of animal cell communication, UCSF scientists have discovered that typical cells in animals have the ability to transmit and receive biological signals by making physical contact with each other, even at long distance.

The mechanism is similar to the way neurons communicate with other cells, and contrasts the standard understanding that non-neuronal cells "basically spit out signaling proteins into extracellular fluid and hope they find the right target," said senior investigator Thomas B. Kornberg, PhD, a professor of biochemistry with the UCSF Cardiovascular Research Institute.

The paper was published on January 2, 2014 in Science.

Working with living tissue from Drosophila fruit flies Kornberg and his team demonstrated that cells send out long, thin tubes of cytoplasm called cytonemes, which Kornberg said "can extend across the length of 50 or 100 cells" before touching the cells they are targeting. The point of contact between a cytoneme and its target cell acts as a communications bridge between the two cells.

"It's long been known that neurons communicate in a similar way by transferring signals at points of contact called synapses, and transmitting the response over long distances in long tubes called axons," said Kornberg. "However, it's always been thought that this mode of signaling was unique to neurons. We have now shown that many types of animal cells have the same ability to reach out and synapse with one another in order to communicate, using signaling proteins as units of information instead of the neurotransmitters and electrical impulses that neurons use."

In fact, said Kornberg, "I would argue that the only strong experimental data that exists today for a mechanism by which these signaling proteins move from one cell to another is at these points of contact and via cytonemes."

However, he noted, "There ar
'/>"/>

Contact: Peter Farley
peter.farley@ucsf.edu
415-502-6397
University of California - San Francisco
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Penn-led team reduces toxicity associated with Lou Gehrigs disease in animal models
2. Serengetis animals under pressure
3. Understanding ourselves by studying the animal kingdom
4. Bacteria may allow animals to send quick, voluminous messages
5. A fish that pushes in the wrong direction solves a mystery of animal locomotion
6. Animal welfare scientists reveal infrequent and inconsistent acceptance of existing data by EPA to satisfy endocrine disruptor testing requirements
7. Tagging aquatic animals can disrupt natural behavior
8. Aboriginal hunting practice increases animal populations
9. Why plants usually live longer then animals
10. Clean living is a luxury wild animals cant afford, study suggests
11. Coastal animals have their own tidal timer -- separate from the 24-hour body clock
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2014)... In a paper published online today in the journal ... Northeastern researchers Evan Kodra and Auroop Ganguly found that ... the variability in temperature extremes. For instance, while each ... those averages will also tend to fall within a ... than are currently being observed. This means that even ...
(Date:7/29/2014)... warms and sea ice retreats, the North is changing. ... open water which is predicted to extend across the ... Storms thus have the potential to create Arctic swell ... unpredictable element to the region. , A University of Washington ... middle of the Arctic Ocean, and detected house-sized waves ...
(Date:7/29/2014)... Research and Markets  has announced the ... Market 2014-2018" report to their offering. ... term BI refers to applications and technologies that are ... about a company,s operations. BI help organizations to acquire ... example, metrics on sales, production, and internal operations. ...
Breaking Biology News(10 mins):Big data confirms climate extremes are here to stay 2Huge waves measured for first time in Arctic Ocean 2Huge waves measured for first time in Arctic Ocean 3Global SaaS-based Business Intelligence (BI) Market 2014-2018 2
... turmeric packs more than just flavor it shows ... Curcumin, found in turmeric, stopped the potentially ... cells, says Aarthi Narayanan, lead investigator on the new ... Center for Biodefense and Infectious Diseases. Mosquito-borne Rift ...
... COLUMBUS, Ohio - Almost 41 percent of Ohioans have visited ... the past year, and of those, nearly one-half usually spend ... findings in a new report. These figures and other ... lakes and rivers, and particularly Lake Erie, as natural resources, ...
... tale of your family line. It carries the genetic history ... Tel Aviv University researcher, it,s also possible to use it ... Halperin of TAU,s Blavatnik School of Computer Science and Department ... researchers from University of California, Los Angeles, are giving new ...
Cached Biology News:Turmeric spices up virus study 2Turmeric spices up virus study 3Ohioans love their lakes, but are concerned for their future 2Ohioans love their lakes, but are concerned for their future 3Ohioans love their lakes, but are concerned for their future 4A GPS in your DNA 2
(Date:7/30/2014)... 2014 With the accelerated aging ... health expenditure as well as the improved medical ... diagnostic reagent industry has been developing quickly, especially ... 2013, Chinese in vitro diagnostics market size reached ... in vitro diagnostic reagents. , Read complete ...
(Date:7/30/2014)... (PRWEB) July 30, 2014 BCC Research ... Global Markets for Enzymes in Industrial Applications , the ... to nearly $7.1 billion by 2018, registering a five-year ... is estimated to be recorded in the detergent enzyme ... period. , Enzyme technology has influenced almost every sector ...
(Date:7/30/2014)... AZ (PRWEB) July 30, 2014 ... State-of-the-art facility and complementary therapies brings comprehensive cancer ... foot, state-of-the-art Yuma Regional Cancer Center has officially ... 2012, the program includes services such as open, ... massage therapy, American Cancer Society Resource Center, hematology, ...
(Date:7/30/2014)... , July 30, 2014  Dyadic International, ... company whose patented and proprietary technologies are used ... other proteins for the bioenergy, bio-based chemical, biopharmaceutical ... of Thomas "Tom" Dubinski as Vice President and ... leading the financial and information technology operations for ...
Breaking Biology Technology:China Diagnostic Reagent Industry Report, 2013-2016 | Researchmoz 2China Diagnostic Reagent Industry Report, 2013-2016 | Researchmoz 3Global Market for Industrial Enzymes to Reach Nearly $7.1 Billion by 2018; Detergent Enzyme Market to Record Maximum Growth 2Global Market for Industrial Enzymes to Reach Nearly $7.1 Billion by 2018; Detergent Enzyme Market to Record Maximum Growth 3Sate-of-the-Art Yuma Regional Cancer Center Officially Opens 2Thomas Dubinski joins Dyadic as Chief Financial Officer 2Thomas Dubinski joins Dyadic as Chief Financial Officer 3Thomas Dubinski joins Dyadic as Chief Financial Officer 4
... Street Healthcare Partners , a strategic private equity firm ... Garrett has joined the firm as an operating partner. ... executive officer of Beckman Coulter, Inc., brings to Water ... care businesses ranging from diagnostics and life sciences to ...
... Fresh®, Inc., maker of the popular FireFly® children,s light-up ... raise awareness and funds for Smile Train, the world,s ... will donate $1 for every new "Like" on ... Train.  The organization provides life-changing surgery for poor children ...
... Gilliam, a famed Hollywood actor and former Golden Gloves ... line of nutritional products. Bubba, who once worked with ... Eastwood, Gene Wilder, Andy Griffith, Jeff Bridges, Hilary Swank, ... Fox, Willie Nelson and more, says, "I,ve never slept ...
Cached Biology Technology:Scott Garrett Joins Water Street Healthcare Partners 2Scott Garrett Joins Water Street Healthcare Partners 3FireFly® Toothbrush Facebook Campaign Raises Funds for Smile Train 2Terra Biotech Goes Hollywood with New Endorsement Burton 'Bubba' Gilliam 2
...
Antibodies were affinity purified using epitopes specific to QKI immobilized on solid support....
Acrylamide, 500 g. Assay: > 99.9%, acrylic acid: < 0.001%. Conductivity (35%): < 2 umhos/cm.Risks: 45, 46, 48, 23, 24, 25 ; Safety Precautions: 53, 44. Category: Nucleotides & Enzymes & Biochemicals...
Assay Diluent Trial Pack, 4 x 100 mL...
Biology Products: