Navigation Links
Analysis of stickleback genome sequence catches evolution in action
Date:4/4/2012

ted in Science that freshwater sticklebacks typically carry certain versions of the gene Ectodysplasin, which helps set the number of bony plates along a fish's side. Rare in marine sticklebacks, the reduced armor variants presumably became prevalent in most streams and lakes because less body armor was advantageous in fresh water, where speed was a better defense against local predators. However, Kingsley notes, this kind of detective work, which focuses on a particular morphological trait, relies on laborious techniques to map and pinpoint evolving genes, and took about five years to complete. In addition, he says, individual case studies can't provide a general picture of the types of DNA changes most often used when fish adapt to new surroundings. To get that overview, the researchers needed the complete stickleback genome sequence.

For their latest study, Kingsley, scientists from the Broad Institute of MIT and Harvard, and an international team of collaborators started by sequencing the genome of an Alaskan freshwater stickleback to serve as a standard for comparison. That was an achievement in itself, yielding the first complete stickleback genome sequence.Next, the team followed suit with the genomes of twenty additional sticklebacks from around the world, including ten ocean stickleback varieties found around North America, Europe, and Japan, as well as the genomes of ten freshwater relatives from nearby freshwater locations. They then analyzed the sequences to identify DNA regions that changed whenever the fish made the move from salt water to fresh.

The researchers found 147 "reused" regions in the fish's genome. That suggests that each time the fish left the sea, variants in this same group of genes helped remodel the fish into forms that were better suited to fresh water, Kingsley says.

So what are these genes? The reused regions include the key armor genes that Kingsley and colleagues previously identified, and many others i
'/>"/>

Contact: Jim Keeley
keeleyj@hhmi.org
301-215-8858
Howard Hughes Medical Institute
Source:Eurekalert

0

GOOD

Page: 1 2 3

Related biology news :

1. A new application allows online statistical analysis of gene-expression data
2. New analysis of premature infants heartbeats, breathing could be cues for leaving NICU
3. Beyond the microscope: Identifying specific cancers using molecular analysis
4. Analysis of generalized linear mixed models
5. Psychemedics Awarded Patent Fundamental To Hair Analysis Drug Testing
6. Sweeping genetic analysis of rare disease yields common mechanism of hypertension
7. Elusive ultrafine indoor air contaminants yield to NIST analysis
8. Report provides new analysis of carbon accounting, biomass use, and climate benefits
9. Deep words, shallow words: An initial analysis of water discourse in 40 years of UN declarations
10. Thin - Film Photovoltaic (PV) Cells Market Analysis to 2020 - CIGS (Copper Indium Gallium Diselenide) to Emerge as the Major Technology by 2020
11. New analysis confirms sharks are in trouble
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/19/2013)... of electricity-producing bacteria that can grow using hydrogen gas ... its sole source of carbon. Researchers at the ... 113th General Meeting of the American Society for Microbiology. ... solely on hydrogen," says Amit Kumar, a researcher on ... of the Lovley Lab Group at the university. , ...
(Date:5/18/2013)... Orlando, FL (May 18, 2013) Research presented today ... liver disease research, with findings about the impact of ... patients. , While coffee consumption recently has been ... found that even a few more cups of java ... particular autoimmune liver disease. Researchers at the Mayo Clinic, ...
(Date:5/17/2013)... 2013) The AGA Research Foundation announced a new ... between the gut microbiota, one of today,s most exciting ... , The AGA Research Awards Panel selected Andrew T. ... Hospital and Harvard Medical School, Boston, as the 2013 ... will receive $25,000 of funding, commencing in July 2013, ...
Breaking Biology News(10 mins):Coffee consumption associated with reduced risk of autoimmune liver disease 2New gut microbiome research to explore red meat -- colorectal cancer pathway 2
... May 7, 2012 - A new innovation can completely reshape ... of genetically engineered (GE) crops in the 1980,s ignited a ... crop yields and better nutritional content, along with the reduction ... play a significant role in the U.S., with more than ...
... research long-term is to develop more efficient biofuel cells, seen ... by readily available biological materials, they have the potential to ... is it not possible to replace a battery or recharge ... process glucose, but the Leeds research will focus on bacterial ...
... in more than 200 outlet glaciers indicates that Greenland,s contribution ... significantly less than the upper limits some scientists thought possible. ... National Science Foundation (NSF) and NASA and published in today,s ... a melting Greenland,s contributions to rising sea levels could be ...
Cached Biology News:New research reveals challenges in genetically engineered crop regulatory process 2New research reveals challenges in genetically engineered crop regulatory process 3Creating energy from light and air - new research on biofuel cells 2Analysis of speed of Greenland glaciers gives new insight for rising sea level 2Analysis of speed of Greenland glaciers gives new insight for rising sea level 3
(Date:5/21/2013)... 21, 2013 PathoGenetix, Inc., a commercial-stage ... typing, announced today that it has successfully identified and ... strains obtained from the Centers for Disease Control and ... technology. The findings are detailed in a poster ... Society for Microbiology in Denver on Monday. , The ...
(Date:5/20/2013)... Oven Industries Inc. announces a new ... 5R6-900 benchtop controller has many outstanding user-friendly benefits. Contained ... into the wall as a self-contained temperature control system, ... makes the device unique, as well as highly convenient ... can also be used universally, which allows the user ...
(Date:5/20/2013)... -- Pacific Biomarkers and Clinigene International are set to ... at the 2013 AAPS/ National Biotechnology Conference ... Marina , San Diego, ... speak with company representatives at their collaborative seminar, "Biosimilarity, ... 21 from 1-2 p.m. in the conference,s Spinnaker Room. ...
(Date:5/20/2013)... May 20, 2013 Rhythm announced today the ... RM-131, the company,s novel ghrelin agonist for the treatment ... trial demonstrated that RM-131 significantly accelerates early gastric emptying ... diabetic patients with diabetic gastroparesis. The findings were presented ... Orlando and recently published in ...
Breaking Biology Technology:New Genotyping System Identifies Pathogenic E. coli Outbreak Strains 2New Genotyping System Identifies Pathogenic E. coli Outbreak Strains 3New Laboratory Temperature Controller by Oven Industries 2Pacific Biomarkers and Clinigene International To Announce Laboratory Solutions for Developers of Biosimilars at 2013 AAPS/ National Biotechnology Conference 2Rhythm Announces Phase 1b Results for Ghrelin Prokinetic RM-131 for Gastroparesis in Patients with Type 1 Diabetes 2Rhythm Announces Phase 1b Results for Ghrelin Prokinetic RM-131 for Gastroparesis in Patients with Type 1 Diabetes 3
... Genetics, Inc., a privately held oncology molecular diagnostics company, ... the company,s President, Chief Executive Officer, and newest member ... Metamark co-founder who previously served as interim CEO, will ... Directors. Mr. Straley brings twenty five years ...
... Mass., Nov. 5, 2010 Tomophase Corporation, a leading ... imaging devices, announced that it has received an award ... Human Services for the Qualifying Therapeutic Discovery Project (QTDP.) ... a federally sponsored program that is targeted to projects ...
... Reports Third Quarter Financial Results ... ... --> ... var first_result; // Results are keyed by longUrl, so we need to grab the first one. for (var r ...
Cached Biology Technology:Metamark Genetics, Inc. Announces New Chief Executive Officer 2Tomophase Receives Qualifying Therapeutic Discovery Project (QTDP) Award 2OncoGenex Reports Third Quarter Financial Results 2OncoGenex Reports Third Quarter Financial Results 3OncoGenex Reports Third Quarter Financial Results 4OncoGenex Reports Third Quarter Financial Results 5OncoGenex Reports Third Quarter Financial Results 6OncoGenex Reports Third Quarter Financial Results 7OncoGenex Reports Third Quarter Financial Results 8OncoGenex Reports Third Quarter Financial Results 9OncoGenex Reports Third Quarter Financial Results 10OncoGenex Reports Third Quarter Financial Results 11OncoGenex Reports Third Quarter Financial Results 12OncoGenex Reports Third Quarter Financial Results 13
Request Info...
PGC-1 (H-300)...
Mouse VEGF R1/Flt-1 Allophycocyanin MAb (Clone 141522) Keywords: Receptor Tyrosine Kinase, RTK, VEGFR1, VEGF Receptor 1 Protein Family: Receptor Tyrosine Kinases, VEGF/PDGF Family...
Mouse Anti-Amyloid beta [1-16], clone 6E10, Monoclonal Antibody...
Biology Products: