Navigation Links
Analysis of RNA role in spreading disease advances study of damaging plant infections
Date:4/21/2008

COLUMBUS, Ohio Recent research that links specific pieces of RNA to an infectious organisms duplication and spread could lead the way to the prevention of viroids, pathogens that can kill or damage food crops and other plants.

The findings and the research approach used by Ohio State University scientists also could have applications in the study of how certain viruses spread in humans because the pathogens have some similar characteristics.

The researchers have developed an experimental system to identify specific structural parts of a viroid that are responsible for its multiplication and spread of the disease.

Because no chemical treatments exist that can specifically inhibit viroid infection, an effective way to prevent viroid multiplication and spread is through genetic alterations of susceptible plants. The best approach to such bioengineering is learning exactly how the pathogens function in the first place, said Biao Ding, senior author of the study and professor of plant cellular and molecular biology at Ohio State.

Were trying to understand how the infection occurs, and how the RNA propagates itself in the cell. But more importantly, even for human diseases, is discovering how a disease spreads. Thats where the problem comes in the plant, Ding said.

Viroids resemble viruses, but consist of only small RNA molecules that dont have the protein coat found on viruses and that dont encode any proteins. Viroids so far have been shown to infect only plants.

Ding and colleagues introduced mutations to specific points within the viroid RNA to see how such disruption affected the role of each piece of the structure. They dont have all of the answers yet to explain the entire viroid RNA function, but their approach shows promise for expanding knowledge about how RNA works in the development of an organism and in the spread of multiple diseases, Ding said.

The research is published in a recent issu
'/>"/>

Contact: Biao Ding
Ding.35@osu.edu
614-247-6077
Ohio State University
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Ginkgo SRMs: Tools for product analysis/quality
2. DNA analysis shows true dispersal of protozoa
3. Interacting protein theory awaits test from new neutron analysis tools
4. Analysis of breast and colon cancer genes finds many areas of differences between tumors
5. Tumor genome analysis unveils new insights into lung cancer
6. Powerful integration of lipid metabolic profiling with gene expression analysis
7. Human clones: New U.N. analysis lays out worlds choices
8. More comprehensive analysis of Klamath River basin needed to aid decision makers
9. Analysis calls for medical device information to better serve patients and doctors
10. Avian origins: new analysis confirms ancient beginnings
11. DOE JGI releases a new version of its metagenome data management and analysis system
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/18/2014)... Nov. 18, 2014   EyeLock Inc. , ... and MorphoTrust USA (Safran), a leading ... announced a strategic partnership to offer comprehensive biometric ... administration (MVA), airport screening and financial services markets. ... MorphoTrust serves consumers through a nationwide network of ...
(Date:11/12/2014)... , Nov. 12, 2014 Crossmatch™, a ... that its U.are.U ® fingerprint readers have been ... in Central Mexico . The bakery ... to eliminate payroll issues caused by employees clocking in ... the U.are.U fingerprint readers, Montparnasse relied on paper timecards ...
(Date:11/10/2014)... U.S. store shelves in early 2010, and people have ... packets can be tossed into a washing machine without ... The convenience, though, has come with risks for young ... Children,s Hospital found that from 2012 through 2013, U.S. ... than 6 years of age swallowing, inhaling, or otherwise ...
Breaking Biology News(10 mins):EyeLock, MorphoTrust Form Strategic Partnership to Pursue Commercial Enterprise Deployments 2EyeLock, MorphoTrust Form Strategic Partnership to Pursue Commercial Enterprise Deployments 3Montparnasse Pasteleria Achieves Time and Attendance Transparency with Crossmatch U.are.U Fingerprint Readers 2Study finds laundry detergent pods, serious poisoning risk for children 2
... Jan. 7, 2013 Halting climate change will require "a ... eradicate harmful carbon dioxide emissions, not just stabilize them, according ... In a Jan. 9 paper in Environmental Research Letters ... take a fresh look at the popular "wedge" approach to ...
... from Italy and their offspring form one of the largest ... their state of health and risk of mortality. In a ... University of Zurich,s Institute of Social and Preventative Medicine calculated ... Immigrants from Italy live longer than ...
... New research led by the Karolinska Institutet, Sweden and the ... human gene and the composition of human gastrointestinal bacteria. In ... Gut , the team outline new evidence suggesting that the ... of the billions of microbes in the human gastrointestinal tract ...
Cached Biology News:Major cuts to surging CO2 emissions are needed now, not down the road, study finds 2Italian immigrants live longer 2International study suggests human genes influence gut microbial composition 2
(Date:12/19/2014)... In contrast to traditional LED lights where ... Valoya uses proprietary LED technology to incorporate their spectra ... which is critical in low proximity installations. The Valoya ... its lifetime which is up to four times longer ... investment cost was clearly higher when compared to traditional ...
(Date:12/19/2014)... Dec. 18, 2014  Decision Resources Group finds that ... market will grow moderately through 2023 as the aging ... awareness of dental biomaterials all spur procedure volumes. Growth ... China and India ... procedures within reach for a larger proportion of the ...
(Date:12/19/2014)... NEW YORK , Dec. 18, 2014 ... novel therapies for the treatment of chronic pain, announced ... held today. "This was a transformational year ... a promising future for our company," said Sergio ... past year, we have executed on key financial, human ...
(Date:12/17/2014)... “Never say, ‘I cannot do ... Department of Physics, advises young women pursuing careers ... SPIE Women in Optics 18-month planner ... ask questions.” , In the annual planner, women ... ranging from university professor and laboratory researcher to ...
Breaking Biology Technology:Asia Pacific Dental Biomaterial Market Will Grow Strongly Through 2023 2Asia Pacific Dental Biomaterial Market Will Grow Strongly Through 2023 3Relmada Therapeutics Announces Results of Annual Shareholders Meeting 2Network, Multitask, Persevere: SPIE Women in Optics Planner Subjects Share from Experience 2Network, Multitask, Persevere: SPIE Women in Optics Planner Subjects Share from Experience 3
... 20, 2011 Scientists Drs. Samuel and Elenore Bogoch of ... increase in Replikin Counts of the EHEC lethal strains of ... strains of E. Coli have been studied in laboratories in ... available in the public databases. Replikins are subsequences of the ...
...   Hospitals, health systems to ... Sigma and other,performance management solutions ... information products,and services, has struck an exclusive partnership with ... online learning solutions for process,improvement. Elsevier will ...
... has the potential to make consumer electronic devices faster ... scale of electronics, also make graphene difficult to fabricate ... In September 2010, a UCLA research team reported ... were able to fabricate graphene transistors with unparalleled speed. ...
Cached Biology Technology:Rising Replikin Counts in E. Coli in Germany Since 2005 Preceded Current E. Coli Outbreak 2Rising Replikin Counts in E. Coli in Germany Since 2005 Preceded Current E. Coli Outbreak 3Elsevier Strikes Exclusive eLearning Partnership with The Quality Group 2Elsevier Strikes Exclusive eLearning Partnership with The Quality Group 3Elsevier Strikes Exclusive eLearning Partnership with The Quality Group 4UCLA team reports scalable fabrication of self-aligned graphene transistors, circuits 2
SCCRO (S-17)...
... is specifically designed to target and display ... cerevisiae. Displayed proteins can be analyzed for ... putative ligands. pYD1 uses the a-agglutinin yeast ... Aga1 and Aga2 to display recombinant protein ...
... 15(S)-15-methyl PGF2α is a ... It is a potent uterine ... be administered intramuscularly to induce ... reduces serum progesterone concentrations when ...
... media are neutral, porous styrene ... chromatography of lipophilic polymers and ... eluents. The beads are compatible ... tetrachloride, dimethylformamide, ketones, aromatics, methylene ...
Biology Products: