Navigation Links
An unexpected player in a cancer defense system
Date:11/28/2011

erent outcome. The work shows that VCP/p97 facilitates the binding of 53BP1 by removing a protein that occupies the places where 53BP1 can bind. So instead of unwinding a protein to prepare it for destruction, VCP/p97 pulls a protein out of the way for 53BP1. The researchers also show that worms that have less of this complex are very sensitive to DNA damage supporting an important and evolutionary conserved role of VCP/p97 in DNA damage control. This new mechanism of recruiting a protein by removing another one that gets in the way sheds new light onto how the tumor suppressor 53BP1 finds damaged DNA. An important question that remains is if VCP/p97 plays similar roles in other processes.


'/>"/>

Contact: Press Office
pressinfo@ki.se
46-852-486-077
Karolinska Institutet
Source:Eurekalert

Page: 1 2

Related biology news :

1. Study of placenta unexpectedly leads to cancer gene
2. Unexpected finding opens up new way to stop autoimmune diseases and transplant rejection
3. New and unexpected mechanism identified how the brain responds to stress
4. Red pandas reveal an unexpected (artificial) sweet tooth
5. Yeast missing sex genes undergo unexpected sexual reproduction
6. Salt block unexpectedly stretches in Sandia experiments
7. 1-finger exercise reveals unexpected limits to dexterity
8. New study reveals unexpected relationship between climate warming and advancing treelines
9. Study points to new uses, unexpected side effects of already existing drugs
10. Research reveals lipids unexpected role in triggering death of brain cells
11. Study reveals H1N1 unexpected weakness
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/19/2014)... and other science courses are increasingly being asked ... they have a new textbook to help them ... this month by Princeton Press and co-authored by ... Biological Synthesis (NIMBioS), teaches readers about basic mathematical ... explore and explain biological phenomena. , Suitable for ...
(Date:8/19/2014)... a glass of fizzy soda knows that bubbles can ... finding with wide industrial applications, Princeton researchers have demonstrated ... the liquid as well. , "It is well known ... surprised, and fascinated, to discover that when we covered ... oil droplets into the water," said Howard Stone, the ...
(Date:8/19/2014)... 19 August 2014: An engineer at the University of ... having a brain to communicate with the body. , ... L Mahadevan, has developed a mathematical model for earthworms ... how these soft bodied animals get around. , The ... pattern generator (CPG) which states that the central brain ...
Breaking Biology News(10 mins):New textbook introduces undergraduates to mathematics for the life sciences 2Bubbling down: Discovery suggests surprising uses for common bubbles 2Bubbling down: Discovery suggests surprising uses for common bubbles 3Secrets of how worms wriggle uncovered 2
... TXService learning involves the incorporation of community service into ... In the service learning model, students participate in ,real ... community. Researchers T.M. Waliczek and J.M. Zajicek reported on ... horticulture course in HortTechnology . The team found ...
... June 23, 2011 UT Southwestern Medical Center ... signaling pathway in Huntington,s disease, a finding that may ... slow the progression of degenerative nerve disorders. "Our ... disease treatment and possibly for other neurodegenerative diseases," said ...
... began working with legendary drug developer Paul Janssen, founder of ... an effort to create new and potent drugs to fight ... second anti-HIV drug that came from this collaboration., "For ... countless obstacles must be overcome," said Eddy Arnold, Board of ...
Cached Biology News:Service projects increase learning, social impact for undergrads 2Compound may provide drug therapy approach for Huntington's disease 2Rutgers laboratory helped to create new HIV drug 2Rutgers laboratory helped to create new HIV drug 3
(Date:8/18/2014)... (PRWEB) August 18, 2014 Global HIV ... pharma report announced by Reportstack. The rate of HIV infection ... on a declining note at a positive rate across the ... from 2.3 million in 2005 to 1.5 in 2013, with ... cause for such drastic changes in the infection rates has ...
(Date:8/18/2014)... , Aug. 18, 2014 TNI BioTech, ... company pioneering the manufacturing and marketing of innovative therapies ... the Company is providing a second notice of TNI ... In making the announcement, Noreen Griffin , founder ... in advance for your participation in the Annual Meeting. ...
(Date:8/18/2014)... August 2014 Vier führende deutsche ... klinische Studie auf, in der eine Intraokularlinse ... das Sehvermögen bei allen Entfernungen verbessern, so ... keine Lese- oder Gleitsichtbrille mehr benötigen. Die ... FluidVision Accommodating Intraocular Lens (FluidVision akkomodative ...
(Date:8/16/2014)... a way to make atomic-force microscope probes 20 times ... as the weight of an individual virus. , The ... (ANU), hinges on using laser beams to cool a ... level of sensitivity achieved after cooling is accurate enough ... virus that is 100 billion times lighter than a ...
Breaking Biology Technology:Global HIV Infection Drug Market Overview 2Global HIV Infection Drug Market Overview 3Global HIV Infection Drug Market Overview 4TNI BioTech Inc., provides 2nd Notice of Annual Meeting September 4, 2014 2TNI BioTech Inc., provides 2nd Notice of Annual Meeting September 4, 2014 3TNI BioTech Inc., provides 2nd Notice of Annual Meeting September 4, 2014 4Implantation einer revolutionären akkommodativen Linse bei Katarakt-Patienten in deutschen Augenzentren im Rahmen einer internationalen klinischen Studie 2Implantation einer revolutionären akkommodativen Linse bei Katarakt-Patienten in deutschen Augenzentren im Rahmen einer internationalen klinischen Studie 3Implantation einer revolutionären akkommodativen Linse bei Katarakt-Patienten in deutschen Augenzentren im Rahmen einer internationalen klinischen Studie 4Laser makes microscopes way cooler 2
... , , , ... Healthcare today released new survey results revealing that 85 percent of ... concern. Yet, when asked about testing their children for allergies, ... options available. Furthermore, more than one-third were not familiar with the ...
... , London, July 20 There has been a ... and biotechnology space. While the economic downturn and related credit crunch ... M&A mania, which has including four mega M&As in the first ... (Logo: http://www.newscom.com/cgi-bin/prnh/20081117/FSLOGO ) , , "The ...
... , , COLUMBIA, Md., July 17 ... DHA, Martek Biosciences (Nasdaq: MATK ), announced today that it ... Food Chain and Animal Health (SCFCAH) of the European Union for additional ... , This is a significant action that will provide ...
Cached Biology Technology:American Mothers Seriously Concerned About Childhood Allergies, Siemens Survey Reveals 2American Mothers Seriously Concerned About Childhood Allergies, Siemens Survey Reveals 3American Mothers Seriously Concerned About Childhood Allergies, Siemens Survey Reveals 4American Mothers Seriously Concerned About Childhood Allergies, Siemens Survey Reveals 5Big Pharma to Big Biopharma: Frost & Sullivan Examines the Latest M&A Trends and Opportunities 2EU Committee Approves New Food Applications for Martek's life'sDHA(TM) 2EU Committee Approves New Food Applications for Martek's life'sDHA(TM) 3