Navigation Links
An advance toward blood transfusions that require no typing
Date:3/9/2011

Scientists are reporting an "important step" toward development of a universal blood product that would eliminate the need to "type" blood to match donor and recipient before transfusions. A report on the "immunocamouflage" technique, which hides blood cells from antibodies that could trigger a potentially fatal immune reaction that occurs when blood types do not match, appears in the ACS journal, Biomacromolecules.

Maryam Tabrizian and colleagues note that blood transfusions require a correct match between a donor and the recipient's blood. This can be a tricky proposition given that there are 29 different red blood cells types, including the familiar ABO and Rh types. The wrong blood type can provoke serious immune reactions that result in organ failure or death, so scientists have long sought a way to create an all-purpose red blood cell for transfusions that doesn't rely on costly blood typing or donations of a specific blood type.

To develop this "universal" red blood cell, the scientists discovered a way to encase living, individual red blood cells within a multilayered polymer shell. The shell serves as a cloaking device, they found, making the cell invisible to a person's immune system and able to evade detection and rejection. Oxygen can still penetrate the polymer shell, however, so the red blood cells can carry on their main business of supplying oxygen to the body. "The results of this study mark an important step toward the production of universal RBCs," the study states.


'/>"/>

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert

0

GOOD

Page: 1

Related biology news :

1. Stevens awarded $1M for advanced biofuels research
2. Taking the next step toward advanced artificial limbs
3. Advance offers revolution in food safety testing
4. Sig-Tec(R) and BIO-key(R) Deliver Advanced Biometric Security Solution to Ohio County Law Enforcement Agency
5. New data resource to advance computer-aided drug design
6. Annual Bibliography of Significant Advances in Dietary Supplement Research 2007
7. New book includes advances in the science and practice of transfusion and transplantation
8. State fund advances titanium powder research, 9 other Iowa State projects
9. Brandeis and Smart Balance team up to advance heart-healthy research
10. Marine invasive species advance 50km per decade, World Conference on Marine Biodiversity told
11. Clemson researchers advance nano-scale electromechanical sensors
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/22/2013)... YORK CITY, May 22, 2013 U.S. Forest Service ... team that, with funding from the TKF Foundation, will ... help communities and individuals recover from tragedy. , The ... one of six projects selected for grant funding. In ... and sacred spaces in recovery and resiliency, the 3-year, ...
(Date:5/22/2013)... 22, 2013)The omega 3 fatty acids in fish oil ... much so that the American Heart Association currently recommends ... particularly fatty varieties rich in omega 3s. However, the ... In a new study, scientists led by Jason R. ... phenomenon by providing evidence that fish oil might specifically ...
(Date:5/22/2013)... on how climate change will affect interactions between species ... Journal of Animal Ecology . This knowledge, they say, ... of how species are likely to be impacted by ... recognition among biologists that climate change is affecting how ... going to have very important consequences for the stability ...
Breaking Biology News(10 mins):'Landscapes of Resilience' to study how people use nature as a source of recovery 2Fish oil may help the heart beat mental stress 2UCLA life scientists present new insights on climate change and species interactions 2UCLA life scientists present new insights on climate change and species interactions 3UCLA life scientists present new insights on climate change and species interactions 4UCLA life scientists present new insights on climate change and species interactions 5
... Miami Beach, Fla., October 2, 2011 More than three-quarters ... D) and the lowest levels are associated with more advanced ... at the 53rd Annual Meeting of the American Society for ... investigated whether vitamin D has an impact on the prognosis ...
... factor that is crucial for the proper positioning of genes ... of researchers from the Alexander Silberman Institute of Life Sciences ... Institute for Biomedical Research in Basel, Switzerland. The ... element in this proper positioning, the lack of which can ...
... determined that a combination of P16 immunohistochemistry and DNA ... the oropharyngeal squamous cell carcinoma, a form of head ... a study published in Clinical Cancer Research , ... "This has immediate clinical applications as we consider ...
Cached Biology News:Vitamin D deficiency common in cancer patients 2Factor in keeping 'good order' of genes discovered 2
(Date:5/24/2013)... Dr. Ingrid Warmuth and Anamaria Newport, MHS, PA-C, with ... announce an Open House at their Swedesboro location, 95 Woodstown ... from 10 AM to 2 PM. , During the ... will be on hand to talk to people about the ... complimentary cosmetic consultations. There will also be specials offered, such ...
(Date:5/24/2013)... (PRWEB) May 24, 2013 Bed bug cases ... protect themselves from the looming higher risk of becoming the ... a new bed bug guideline. In the guide, the company ... and avoiding them while traveling. , According to ... an increase of bed bug infestation during summer: the warm ...
(Date:5/24/2013)... , May 24, 2013 Senomyx ... using proprietary taste science technologies to discover, develop, and ... David Linemeyer , Ph.D., the Company,s Vice President, ... President, Investor Relations & Corporate Communications, will present an ... 31, at 10:25 a.m. Eastern Time (7:25 a.m. Pacific ...
(Date:5/24/2013)... Many factors impact tissues targeting such as protein ... the blood-tissue barrier. Even when tissue disposition is achieved, ... tissue rather than the total tissue concentration. , A ... guide lead optimization, predict in vivo activity in animal ... impact the likely human clinical dose. , In this ...
Breaking Biology Technology:Steps for Getting Rid of Bed Bugs without Using Chemicals and Avoiding Them While Traveling Enumerated by My Cleaning Products in Its Latest Post 2Steps for Getting Rid of Bed Bugs without Using Chemicals and Avoiding Them While Traveling Enumerated by My Cleaning Products in Its Latest Post 3SENOMYX TO WEBCAST CORPORATE PRESENTATION AT THE CITI 2013 GLOBAL CONSUMER CONFERENCE 2DMPK for Targeted Tissue Delivery: Solutions for the Most Challenging Part of Outsourcing, New Life Science Webinar Hosted by Xtalks 2
... Without clear leadership and more transparency in federal risk ... a happy accident, rather than a foregone conclusion, says ... Project on Emerging Nanotechnologies (PEN). This sentiment was voiced ... Science & Technology Committees hearing on the National Nanotechnology ...
... Life Sciences,Holdings, Inc. (Nasdaq: ADLS ), today ... Capital Market listing requirements. On April,16, 2008, the ... that it has regained compliance with Nasdaq,Marketplace Rule ... Company,s,common stock has been equal to or in ...
... Md., April 16 The Board of Managers ... Dr. Danong Chen has,been elected as the new ... previously the President and CEO of Tanox Inc., ... Genentech in 2007.,Previously Dr. Chen was Vice-President of ...
Cached Biology Technology:Limited transparency in federal nanotech research may hamper development 2Advanced Life Sciences Regains Compliance With Nasdaq Listing Requirements 2Danong Chen appointed CEO of Theranostics Health 2
RAT ANTI MOUSE F4/80 ANTIGEN:BIOTIN Immunogen: Thioglycollate stimulated peritoneal macrophages from C57/BL mice...
Sterile glass 5 mm beads that make spreading bacterial and yeast cultures easy. Can be washed, autoclaved and reused....
REGULATED IN DEVELOPMENT AND DNA DAMAGE RESPONSES 1,HIF-1 responsive RTP801...
4-Hydroxy-3-iodo-5-nitrophenylacetyl hapten is conjugated to BSA protein through lysine by amide bonds....
Biology Products: