Navigation Links
Amniotic fluid yields alternatives to embryonic stem cells
Date:7/3/2012

Stem cells found in amniotic fluid can be transformed into a more versatile state similar to embryonic stem cells, according to a study published today in the journal Molecular Therapy. Scientists from Imperial College London and the UCL Institute of Child Health succeeded in reprogramming amniotic fluid cells without having to introduce extra genes. The findings raise the possibility that stem cells derived from donated amniotic fluid could be stored in banks and used for therapies and in research, providing a viable alternative to the limited embryonic stem cells currently available.

Amniotic fluid surrounds and nourishes the fetus in the womb. It can be extracted through the mother's abdomen using a needle in a process called amniocentesis, which is sometimes used to test for genetic diseases. The fluid contains stem cells that come from the fetus. These cells have a more limited capacity to develop into different cell types than stem cells in the embryo.

The researchers used stem cells from amniotic fluid donated by mothers undergoing amniocentesis for other purposes during the first trimester of pregnancy. The cells were grown on a gelatinous protein mixture in the lab and reprogrammed into a more primitive state by adding a drug called valproic acid to the culture medium. An extensive set of tests found that these reprogrammed cells have characteristics very similar to embryonic stem cells, which are capable of developing into any cell type in the body a property known as pluripotency.

Even after growing in culture for some time, the reprogrammed cells were able to develop into functioning cells of many different types, including liver, bone and nerve cells. They also maintained their pluripotency even after being frozen and rethawed.

The results suggest that stem cells derived from amniotic fluid could be used in treatments for a wide range of diseases. Donated cells could be stored in banks and used in tre
'/>"/>

Contact: Sam Wong
sam.wong@imperial.ac.uk
44-207-594-2198
Imperial College London
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Biological and Pharmaceutical Complex Fluids Conference
2. Engineers use droplet microfluidics to create glucose-sensing microbeads
3. War-related climate change would reduce substantially reduce crop yields
4. Summer camp yields innovative apps
5. New drug-screening method yields long-sought anti-HIV compounds
6. Discovery of plant proteins may boost agricultural yields and biofuel production
7. New screening technique yields elusive compounds to block immune-regulating enzyme
8. ORNL microscopy yields first proof of ferroelectricity in simplest amino acid
9. Fine-scale analysis of the human brain yields insight into its distinctive composition
10. Expedition to undersea mountain yields new information about sub-seafloor structure
11. NIST launches new website to educate industry about alternatives to mercury thermometers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2015)... China , July 31, 2015 The 10 ... will be held by BGI from October 22-25, 2015, in ... The conference is celebrating its 10 th anniversary ... one of the world,s most influential annual meetings in the ... and enjoyable scientific gatherings. ICG-10 focuses on ...
(Date:7/27/2015)... 2015  Synaptics Inc. (NASDAQ: SYNA ), ... announced that Huawei has selected the Synaptics ® ... stylish smartwatch. Huawei chose the state-of-the-art ClearPad capacitive ... and highly responsive human interface qualities such as ... required a classic round watch face and Synaptics ...
(Date:7/23/2015)... 2015 Aware, Inc. (NASDAQ: AWRE ), a ... results for its second quarter ended June 30, 2015.  ... $4.5 million, a decrease of 33% compared to $6.8 million ... second quarter of 2015 was $0.3 million, or $0.01 per ... diluted share, in the same period a year ago.  ...
Breaking Biology News(10 mins):The 10th International Conference on Genomics (ICG-10) to Open in October 2Synaptics Touchscreen Solution Powers New Huawei Watch 2Synaptics Touchscreen Solution Powers New Huawei Watch 3Aware, Inc. Reports Second Quarter 2015 Financial Results 2Aware, Inc. Reports Second Quarter 2015 Financial Results 3Aware, Inc. Reports Second Quarter 2015 Financial Results 4Aware, Inc. Reports Second Quarter 2015 Financial Results 5Aware, Inc. Reports Second Quarter 2015 Financial Results 6
... Stat1, which is involved in cellular immune signaling, scientists have ... efficient. This old protein with a new twist may eventually ... , Stat1 is involved in immune responses that are initiated ... the cells of the immune system in response to challenges ...
... have demonstrated that the brains of alcoholics are ... brains. Symposium speakers at the October 2004 Congress ... Alcoholism in Mannheim, Germany reviewed what is known ... alcohol-related brain shrinkage. Proceedings are published in the ...
... require accurate transmission. Big genes are especially challenging ... lie between long stretches of non-coding elements (introns). ... pasted together to form a template for proteins ... can reduce the expression of a functional protein ...
Cached Biology News:Engineered molecule amplifies body's immune response 2Engineered molecule amplifies body's immune response 3Investigating 'brain shrinkage' in alcoholics 2Investigating 'brain shrinkage' in alcoholics 3Investigating 'brain shrinkage' in alcoholics 4Investigating 'brain shrinkage' in alcoholics 5Carnegie Mellon University research reveals how cells process large genes 2Carnegie Mellon University research reveals how cells process large genes 3
(Date:7/29/2015)... / Japan (Q2 2015: +14% CER / 20% of ... growth in China , as well as solid contributions from ... Europe / Middle East / ... gains in Germany , Turkey and ... / 49% of sales) grew 11%, excluding U.S. HPV sales, on demand across ...
(Date:7/29/2015)... July 29, 2015  HealthSouth Corporation ... largest providers of post-acute healthcare services, offering both ... results of operations for the second quarter ended ... was characterized by strong volume growth in both ... EBITDA," said Jay Grinney, President and Chief Executive ...
(Date:7/29/2015)... ... 29, 2015 , ... G-CON Manufacturing, Inc., the leading prefabricated ... generation cell therapy POD® design. The 2nd generation portfolio not only delivers design ... POD® design. , “G-CON first offered our miniPOD CT product line to ...
(Date:7/29/2015)... ... July 29, 2015 , ... Brady (NYSE:BRC), a global leader ... . To align chemical container labeling with OSHA’s updated Hazard Communication (HazCom) Standard ... an example of an accurate label, and pictogram uses and meanings. , “With ...
Breaking Biology Technology:QIAGEN Reports Results for Second Quarter and First Half of 2015 2QIAGEN Reports Results for Second Quarter and First Half of 2015 3QIAGEN Reports Results for Second Quarter and First Half of 2015 4QIAGEN Reports Results for Second Quarter and First Half of 2015 5QIAGEN Reports Results for Second Quarter and First Half of 2015 6QIAGEN Reports Results for Second Quarter and First Half of 2015 7QIAGEN Reports Results for Second Quarter and First Half of 2015 8QIAGEN Reports Results for Second Quarter and First Half of 2015 9QIAGEN Reports Results for Second Quarter and First Half of 2015 10HealthSouth Reports Results for Second Quarter 2015 2HealthSouth Reports Results for Second Quarter 2015 3HealthSouth Reports Results for Second Quarter 2015 4HealthSouth Reports Results for Second Quarter 2015 5HealthSouth Reports Results for Second Quarter 2015 6HealthSouth Reports Results for Second Quarter 2015 7HealthSouth Reports Results for Second Quarter 2015 8HealthSouth Reports Results for Second Quarter 2015 9HealthSouth Reports Results for Second Quarter 2015 10HealthSouth Reports Results for Second Quarter 2015 11HealthSouth Reports Results for Second Quarter 2015 12HealthSouth Reports Results for Second Quarter 2015 13HealthSouth Reports Results for Second Quarter 2015 14HealthSouth Reports Results for Second Quarter 2015 15HealthSouth Reports Results for Second Quarter 2015 16HealthSouth Reports Results for Second Quarter 2015 17HealthSouth Reports Results for Second Quarter 2015 18HealthSouth Reports Results for Second Quarter 2015 19HealthSouth Reports Results for Second Quarter 2015 20HealthSouth Reports Results for Second Quarter 2015 21HealthSouth Reports Results for Second Quarter 2015 22HealthSouth Reports Results for Second Quarter 2015 23HealthSouth Reports Results for Second Quarter 2015 24HealthSouth Reports Results for Second Quarter 2015 25HealthSouth Reports Results for Second Quarter 2015 26HealthSouth Reports Results for Second Quarter 2015 27
... , , SALT LAKE ... spine care through the development of molecular diagnostics, announced today ... available to spine specialists in the United States. SCOLISCORE is ... progression of scoliosis, an abnormal lateral curvature of the spine. ...
... , LANSING, Mich., Sept. 24 Neogen Corporation (Nasdaq: ... first quarter of FY 2010, which ended Aug. 31, increased 12% ... income increased 18% from the prior year,s $3,733,000 to $4,395,000, or ... previous year,s $0.25. , , Neogen,s first quarter ...
... ... round of funding. Participating investors included CTTV Investments LLC, the venture capital arm ... , ... CA (PRWEB) September 24, 2009 -- LS9, Inc., the Renewable Petroleum Company™, today announced ...
Cached Biology Technology:Axial Biotech Announces Commercial Availability of SCOLISCORE(TM) AIS Prognostic Test 2Axial Biotech Announces Commercial Availability of SCOLISCORE(TM) AIS Prognostic Test 3Neogen Reports 18% Increase in Net Income, 12% Increase in Revenues 2Neogen Reports 18% Increase in Net Income, 12% Increase in Revenues 3Neogen Reports 18% Increase in Net Income, 12% Increase in Revenues 4Neogen Reports 18% Increase in Net Income, 12% Increase in Revenues 5Neogen Reports 18% Increase in Net Income, 12% Increase in Revenues 6LS9 Secures $25 Million in Latest Round of Funding 2LS9 Secures $25 Million in Latest Round of Funding 3
...
Phosphate-Buffered Saline (PBS) 7.4 (1X) liquid...
...
... Antibody to Human CD66 acd ... by human neutrophils and cells in ... YTH71.3 reacts with transfectants containing BGPa, ... subfamily members(2). Immunogen: ...
Biology Products: