Navigation Links
Amniotic fluid may provide new source of stem cells for future therapies
Date:3/31/2009

ed to destroy their capacity to produce blood cells and injected with either AFKL cells or fetal liver cells. Fetal liver was used for comparison as it is the primary source for hematopoietic cells in developing embryos.

The peripheral blood of the transplanted mice was examined every four weeks, and after 16-18 weeks the blood-forming organs (bone marrow, spleen, thymus, and lymph nodes) of the mice were dissected. Transplants using mouse AFKL cells were found to be successful; newly formed white blood cells of all lineages derived from AFKL cells appeared in most of the irradiated mice four weeks after the procedure. As expected, all of these blood cell types were detected in all of the control group mice who received fetal liver cell transplants. Scientists continued to find AFKL-derived cells in the irradiated mice four months later, demonstrating the long-term ability of the transplanted cells to produce new blood cells.

Bone marrow samples from the transplanted mice were also taken and injected in a second set of mice and the peripheral blood of this new group of irradiated mice was analyzed and their hematopoietic organs examined after 10-13 weeks. The secondary transplants with mouse AFKL cells were partially successful with some of the mice engrafting the donor cells. This finding shows that AFKL cells have the ability to self-renew, a key characteristic of stem cells.

Though the human AFKL cells failed to reconstitute the hematopoietic system in irradiated, immunodeficient mice, experiments are currently underway to overcome obstacles that may have led to this failure, such as using a low number of cells for the injection and conducting the transplant in adult mice (engraftment is easier to obtain in newborn mice).

As additional confirmation of the probability that AFKL cells are indeed stem cells, the researchers examined them for the expression of specific genes known to be involved in hematopoietic development. The ov
'/>"/>

Contact: Patrick C. Irelan
pirelan@hematology.org
202-776-0544
American Society of Hematology
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Uncultured bacteria found in amniotic fluids of women who experience preterm births
2. Study: Fluid buildup in lungs is part of the damage done by the flu
3. GEN reports on growing reliance on microfluidics technology
4. Animal and biological science highlights: San Antonio Fluid Dynamics Conference, Nov. 23-25
5. Kalyon wins Thomas Baron Award in Fluid-Particle Systems
6. Water is designer fluid that helps proteins change shape, scientists say
7. Automated microfluidic device reduces time to screen small organisms for genetic studies
8. Hyperviscous fluids: Better treatment for severe blood loss
9. Magnetic snakes control fluids, gravity-defying droplets, and solving a dragonfly mystery
10. Lohafex provides new insights on plankton ecology
11. VeriLook Surveillance SDK Provides Real-Time Face Identification Using Video Surveillance Cameras
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/15/2014)... and to an unexpected extent. The outbreak does not ... virus shows a new disease dynamic in regions, where ... the German National Academy of Sciences Leopoldina, acatech – ... Union of the German Academies of Sciences and Humanities ... , In the statement the academies call for the ...
(Date:10/15/2014)... , Oct. 15, 2014 NXT-ID, Inc. (NASDAQ: ... authentication company focused on the growing mobile commerce market releases photos ... in Times Square on Monday October 13 th . ... David Tunnel and angel investor Mr. Chad A. ... , CEO of NXT-ID thanked his investors and employees "for their ...
(Date:10/15/2014)... VILNIUS, Lithuania , Oct. 15, 2014 /PRNewswire/ ... identification technologies, today announced the availability of the ... . VeriLook Surveillance 3.0 provides real-time biometric face ... multiple high-resolution digital surveillance cameras. The new version ... detects and differentiates people from objects while they ...
Breaking Biology News(10 mins):Academies call for consequences from the Ebola virus epidemic 2Academies call for consequences from the Ebola virus epidemic 3Academies call for consequences from the Ebola virus epidemic 4Academies call for consequences from the Ebola virus epidemic 5Photo Release: NXT-ID Inc. Rings Opening Bell of the NASDAQ Stock Market October 13th 2Photo Release: NXT-ID Inc. Rings Opening Bell of the NASDAQ Stock Market October 13th 3VeriLook Surveillance 3.0 SDK Identifies Faces and Moving Objects, Differentiates Pedestrians from Other Moving Objects in Video Surveillance Systems 2VeriLook Surveillance 3.0 SDK Identifies Faces and Moving Objects, Differentiates Pedestrians from Other Moving Objects in Video Surveillance Systems 3
... the Rosetta Stone resolved a longstanding puzzle, permitting the ... John Chaput, a researcher at Arizona State University,s ... Stonean enzyme allowing DNA,s 4-letter language to be written ... may have existed as a genetic pathway to DNA ...
... University of Bristol, and his team at the University of Queensland ... the Landolt C test to discover just how fine a detail ... to spit at one of two letters an ,O, or ... showed them small versions of both letters together and recorded which ...
... LAFAYETTE, Ind. - New research findings may help scientists ... potentially fatal brain swelling and paralysis in children., The ... disease and is common throughout the world. Although that ... reported to cause fatal encephalitis in infants and young ...
Cached Biology News:Enzymes allow DNA to swap information with exotic molecules 2Enzymes allow DNA to swap information with exotic molecules 3Enzymes allow DNA to swap information with exotic molecules 4Archerfish get an eye test 2Findings to help in design of drugs against virus causing childhood illnesses 2
(Date:10/19/2014)... 2014 The report "Chocolate, Cocoa Beans, ... Prices, Geography Trend and Forecast (2011 - 2016)," ... geography and studies the major market drivers, restraints, and ... and Asia. , The global chocolate market is expected ... in 2016 at an estimated CAGR of 2.7% from ...
(Date:10/19/2014)... 2014 According to market research ... WLAN Controllers; Wireless gateways)]- Global Advancements, Forecasts and ... global Outdoor Wi-Fi market with analysis and forecasting ... also identifies the drivers and the restrains for ... opportunities and challenges. , Browse 65 market data ...
(Date:10/18/2014)... 18, 2014 The report "1,6-Hexanediol ... and Forecasts to 2019", analyzes the global market ... to understand the industry details such as the ... various geographic regions. , Browse 81 Market Data ... and in-depth TOC on “1,6-Hexanediol Market by Application ...
(Date:10/18/2014)... The Asia-Pacific Liquid Crystal on Silicon (LCoS) ... in Asia-Pacific with analysis and forecast of revenue. This ... is expected to reach $380.0 million by 2018, at ... Browse through the TOC of the Asia-Pacific LCoS display ... analysis provided. This also provides a glimpse of the ...
Breaking Biology Technology:Chocolate Market Projected To Reach $98.3 Billion by 2016 - New Report by MarketsandMarkets 2Chocolate Market Projected To Reach $98.3 Billion by 2016 - New Report by MarketsandMarkets 3Chocolate Market Projected To Reach $98.3 Billion by 2016 - New Report by MarketsandMarkets 4Outdoor Wi-Fi Market (by Access Points, WLAN Controllers, Wireless gateways) Expected to Cross $37.2 Billion by 2018 - New Report by MarketsandMarkets 2Outdoor Wi-Fi Market (by Access Points, WLAN Controllers, Wireless gateways) Expected to Cross $37.2 Billion by 2018 - New Report by MarketsandMarkets 3Outdoor Wi-Fi Market (by Access Points, WLAN Controllers, Wireless gateways) Expected to Cross $37.2 Billion by 2018 - New Report by MarketsandMarkets 41,6-Hexanediol Market Projected to Reach $916.1 Million at a CAGR of 8.3% by 2019 – Report by MarketsandMarkets 21,6-Hexanediol Market Projected to Reach $916.1 Million at a CAGR of 8.3% by 2019 – Report by MarketsandMarkets 31,6-Hexanediol Market Projected to Reach $916.1 Million at a CAGR of 8.3% by 2019 – Report by MarketsandMarkets 41,6-Hexanediol Market Projected to Reach $916.1 Million at a CAGR of 8.3% by 2019 – Report by MarketsandMarkets 5The Asia-Pacific Liquid Crystal on Silicon (LCoS) display market is expected to reach $380.0 million by 2018 - New Report by MicroMarket Monitor 2The Asia-Pacific Liquid Crystal on Silicon (LCoS) display market is expected to reach $380.0 million by 2018 - New Report by MicroMarket Monitor 3
... GenVault Corporation today,announces Paul J. Mirabella, Chairman ... its Board of Directors. Mr. Mirabella has more ... GE Healthcare where he held,leadership roles in technology, ... background in diagnostics and the healthcare,market, he will ...
... Ardea Biosciences, Inc.,(Nasdaq: RDEA ) today announced the ... "We are pleased to welcome Mr. Johnson to ... said Barry D. Quart, PharmD, Ardea,Biosciences, President and CEO. ... will chair our Audit Committee. We look,forward to his ...
... 12 Raymond J. De,Hont, Chairman and Chief Executive ... Company,s Fybroc business unit has received,an order for approximately ... the second and third quarters of the Company,s current ... large order Fybroc has received this year from the,Eastern ...
Cached Biology Technology:Paul J. Mirabella, President and CEO of Naviscan PET Systems Inc., Joins GenVault's Board of Directors 2Craig Johnson Joins Ardea Biosciences' Board of Directors 2Craig Johnson Joins Ardea Biosciences' Board of Directors 3Met-Pro Corporation's Fybroc Business Unit Receives Equipment Order Totaling Approximately $500,000 2Met-Pro Corporation's Fybroc Business Unit Receives Equipment Order Totaling Approximately $500,000 3
Clarin Mounting Medium (Permanent environmentally safe mounting medium for general histology & cytology use)...
IHC Zinc Fixative - , 1000 ml Consult technical datasheet for details....
Rabbit polyclonal to JNK1 (phospho T183 + Y185) ( Abpromise for all tested applications). entrezGeneID: 5599 SwissProtID: P45983...
Cytofix Buffer 100 mls...
Biology Products: